Morten Heiberg Bestle
Clinical Professor
- 2024
- Published
Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL)
on behalf of the REVIVAL investigators, O. B. O. T. R. I., Jan 2024, In: Intensive Care Medicine. 50, 1, p. 68-78 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Furosemide versus placebo for fluid overload in intensive care patients-The randomised GODIF trial second version: Statistical analysis plan
Wichmann, S., Lange, T., Perner, A., Gluud, C., Itenov, T. S., Berthelsen, R. E., Nebrich, L., Wiis, J., Brøchner, A. C., Nielsen, L. G., Behzadi, M. T., Damgaard, K., Andreasen, A. S., Strand, K., Järvisalo, M., Strøm, T., Eschen, C. T., Vang, M. L., Hildebrandt, T., Andersen, F. H. & 14 others, , 2024, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 130-136 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneity of treatment effect of higher dose dexamethasone by geographic region (Europe vs. India) in patients with COVID-19 and severe hypoxemia – a post hoc evaluation of the COVID STEROID 2 trial
Tirupakuzhi Vijayaraghavan, B. K., Granholm, A., Munch, M. W., Kjær, M. B. N., Møller, M. H., Perner, A., Myatra, S. N., Jha, V., Jha, V., Jha, V., Hammond, N., Micallef, S., Venkatesh, B., Hammond, N., Lange, T., Munch, M. W., Myatra, S. N., Tirupakuzhi Vijayaraghavan, B. K., Saseedharan, S., Benfield, T. & 31 others, , 2024, In: The Lancet Regional Health - Southeast Asia. 20, 8 p., 100293.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LASSO regression shows histidine and sphingosine 1 phosphate are linked to both sepsis mortality and endothelial damage
Johansson, Pär Ingemar , Henriksen, H. H., Karvelsson, S. T., Rolfsson, Ó., Schønemann-Lund, M., Bestle, Morten Heiberg & McGarrity, S., 2024, In: European Journal of Medical Research. 29, 1, 14 p., 71.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium
Mortensen, C. B., Andersen-Ranberg, N. C., Poulsen, L. M., Granholm, A., Rasmussen, B. S., Kjær, M. B. N., Lange, T., Ebdrup, B. H., Collet, M. O., Andreasen, A. S., Bestle, M. H., Uslu, B., Pedersen, H. S., Nielsen, L. G., Hästbacka, J., Jensen, T. B., Damgaard, K., Sommer, T., Morgen, M., Dey, N. & 6 others, , 2024, In: Intensive Care Medicine. 50, p. 103–113 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial
Nielsen, F. M., Klitgaard, T. L., Siegemund, M., Laake, J. H., Thormar, K. M., Cole, J. M., Aagaard, S. R., Bunzel, A-M. G., Vestergaard, S. R., Langhoff, P. K., Pedersen, C. H., Hejlesen, J. Ø., Abdelhamid, S., Dietz, A., Gebhard, C. E., Zellweger, N., Hollinger, A., Poulsen, L. M., Weihe, S., Andersen-Ranberg, N. C. & 25 others, , 2024, In: JAMA. 331, 14, p. 1185-1194 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Atrial Fibrillation (AFIB) in the ICU: Incidence, Risk Factors, and Outcomes: The International AFIB-ICU Cohort Study
Wetterslev, M., Hylander Møller, M., Granholm, A., Hassager, C., Haase, N., Lange, T., Myatra, S. N., Hästbacka, J., Arabi, Y. M., Shen, J., Cronhjort, M., Lindqvist, E., Aneman, A., Young, P. J., Szczeklik, W., Siegemund, M., Koster, T., Aslam, T. N., Bestle, M. H., Girkov, M. S. & 31 others, , 2023, In: Critical Care Medicine. 51, 9, p. 1124-1137 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bioimpedance and Duration of Organ Dysfunction in Septic Shock - A Prospective Observational Study
Koch, E. B., Madsen, J. M., Wichmann, S., Bestle, Morten Heiberg & Itenov, Theis Skovsgaard, 2023, In: Journal of Intensive Care Medicine. 38, 10, p. 966-974Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bioimpedance as a measure of fluids in patients with septic shock. A prospective observational study
Madsen, J. M., Itenov, Theis Skovsgaard, Koch, E. B. & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 3, p. 319-328Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical progression, disease severity, and mortality among adults hospitalized with COVID-19 caused by the Omicron and Delta SARS-CoV-2 variants: A population-based, matched cohort study
Harboe, Z. B., Roed, C., Holler, J. G., Khan, F. I., Abdulrahman, A. N. A., Mulverstedt, S. L., Lindgaard-Jensen, B., Bertelsen, B. B., Søborg, C., Nielsen, T. L., Hansen, L. V., Madsen, B. L., Browatzki, A., Eiberg, M., Bernhard, P. H., Pedersen, E. M. J., Egelund, G. B., Dungu, A. M., Sejdic, A., Mathiesen, I. H. M. & 56 others, , 2023, In: PLoS ONE. 18, 4 , 15 p., e0282806.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exhaled nitric oxide in intubated ICU patients on mechanical ventilation—a feasibility study
Kofoed, A., Hindborg, M., Hjembæk-Brandt, J., Sørensen, C. D., Kolpen, Mette & Bestle, Morten Heiberg, 2023, In: Journal of Breath Research. 17, 4, 6 p., 046014.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Existing Data Sources in Clinical Epidemiology: Database of Community Acquired Infections Requiring Hospital Referral in Eastern Denmark (DCAIED) 2018–2021
Holler, J. G., Jensen , Jens-Ulrik Stæhr , Engsig, F. N., Bestle, Morten Heiberg, Lindegaard, Birgitte, Rasmussen, J. H., Bundgård, Henning, Nielsen, F. E., Iversen, Kasper, Larsen, J. J., Holzknecht, Barbara Juliane, Boel, J., Sivapalan, P. & Itenov, Theis Skovsgaard, 2023, In: Clinical Epidemiology. 15, p. 939-955 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Goal-directed fluid removal with furosemide versus placebo in intensive care patients with fluid overload: A randomised, blinded trial (GODIF trial—First version)
Wichmann, S., Schønemann-Lund, M., Perner, Anders, Itenov, Theis Skovsgaard, Lange, Theis, Gluud, C., Berthelsen, R. E., Brøchner, A. C., Wiis, J. & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 4, p. 470-478 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Haloperidol vs. placebo for the treatment of delirium in ICU patients: a pre-planned, secondary Bayesian analysis of the AID–ICU trial
Andersen-Ranberg, N. C., Poulsen, L. M., Perner, Anders, Hästbacka, J., Morgan, M., Citerio, G., Collet, Marie Oxenbøll, Weber, S. O., Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, B., Pedersen, H. S., Nielsen, L. G., Damgaard, K., Jensen, T. B., Sommer, T., Dey, N., Mathiesen, Ole & Granholm, A., 2023, In: Intensive Care Medicine. 49, p. 411–420 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How nurses use National Early Warning Score and Individual Early Warning Score to support their patient risk assessment practice: A fieldwork study
Langkjaer, C. S., Bundgaard, K., Bunkenborg, G., Nielsen, P. B., Iversen, Kasper, Bestle, Morten Heiberg & Bove, D. G., 2023, In: Journal of Advanced Nursing. 79, 2, p. 789-797 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term effects of restriction of intravenous fluid in adult ICU patients with septic shock
Kjær, M. B. N., Meyhoff, T. S., Sivapalan, P., Granholm, A., Hjortrup, P. B., Madsen, M. B., Møller, M. H., Egerod, I., Wetterslev, J., Lange, T., Cronhjort, M., Laake, J. H., Jakob, S. M., Nalos, M., Ostermann, M., Gould, D., Cecconi, M., Malbrain, M. L. N. G., Ahlstedt, C., Kiel, L. B. & 41 others, , 2023, In: Intensive Care Medicine. 49, p. 820–830 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mild induced hypothermia and coagulation and platelet function in patients with septic shock: Secondary outcome of a randomized trial
Itenov, Theis Skovsgaard, Kromann, M. E., Ostrowski, Sisse Rye, Bestle, Morten Heiberg, Mohr, T., Gyldensted, L., Lindhardt, A., Thormar, K., Sessler, D. I., Juffermans, N. P., Lundgren, Jens & Jensen , Jens-Ulrik Stæhr , 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 909-917 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel subgroups in acute respiratory failure based on the trajectories of three endotheliopathy biomarkers: A cohort study
Schønemann-Lund, M., Itenov, Theis Skovsgaard, Larsson, J. E., Lindegaard, Birgitte, Johansson, Pär Ingemar & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 896-908 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PaCO2 trajectories in mechanically ventilated patients with COVID-19: A population-based cohort study
Berg, R. M. G., Ronit, A., Haase, N., Moller, M. H., Kristiansen, K. T. T., Jonassen, T., Wamberg, C., Andreasen, A. S., Mohr, T., Bestle, M. H. H., Jorgensen, V. L. L., Hammer, N. R. R., Mitchell, A. U. U., Smitt, M., Greve, A. M., Nyeland, M. E., Jensen, B. W., Andreasen, A. H., Petersen, J., Solem, E. J. & 2 others, , 2023, In: Acta Anaesthesiologica Scandinavica. 67, 6, p. 779-787 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial
François, B., Lambden, S., Fivez, T., Gibot, S., Derive, M., Grouin, J-M., Salcedo-Magguilli, M., Lemarié, J., De Schryver, N., Jalkanen, V., Hicheur, T., Garaud, J-J., Cuvier, V., Ferrer, R., Bestle, M., Pettilä, V., Mira, J-P., Bouisse, C., Mercier, E., Vermassen, J. & 6 others, , 2023, In: The Lancet Respiratory Medicine. 11, 10, p. 894-904 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pupillary dilation velocity is reduced in intensive care unit patients with septic shock
Uhrenholt, S., Linér, S. M., Stokholm, J., Christensen, T. & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 56-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Study protocol of a randomised, double-blind, placebo-controlled, two-arm parallel-group, multi-centre phase 3 pivotal trial to investigate the efficacy and safety of recombinant human alkaline phosphatase for treatment of patients with sepsis-associated acute kidney injury
Pickkers, P., Angus, D. C., Arend, J., Bellomo, R., Van Den Berg, E., Bernholz, J., Bestle, M., Broglio, K., Carlsen, J., Doig, C. J., Ferrer, R., Joannidis, M., Francois, B., Doi, K., Kellum, J. A., Laterre, P. F., Liu, K., Mehta, R. L., Murray, P. T., Ostermann, M. & 5 others, , 2023, In: BMJ Open. 13, 4, e065613.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The clinical task force: Improving quality of medical students’ internship
Baker, J. J., Weis, Nina, Boysen, T., Bestle, Morten Heiberg, Andersen, A. G., Morcke, A. M. & Bremholm, L., 2023, In: Heliyon. 9, 2, 9 p., e13419.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)
Anthon, C. T., Pène, F., Perner, A., Azoulay, E., Puxty, K., Van De Louw, A., Barratt-Due, A., Chawla, S., Castro, P., Póvoa, P., Coelho, L., Metaxa, V., Kochanek, M., Liebregts, T., Kander, T., Hästbacka, J., Andreasen, J. B., Péju, E., Nielsen, L. B., Hvas, C. L. & 101 others, , 2023, In: Intensive Care Medicine. 49, 11, p. 1327-1338 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Agents intervening against delirium in the intensive care unit trial — Protocol for a secondary Bayesian analysis
Andersen-Ranberg, N., Poulsen, L. M., Perner, Anders, Hästbacka, J., Morgan, M. P. G., Citerio, G., Oxenbøll-Collet, M., Weber, S., Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, B., Pedersen, H. B. S., Nielsen, L. G., Damgaard, K., Jensen, T. B., Sommer, T., Dey, N., Mathiesen, Ole & Granholm, A., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 7, p. 898-903Research output: Contribution to journal › Journal article › Research › peer-review
ID: 32365843
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Heat Stroke: A Medical Emergency Appearing in New Regions
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199
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Intervention fidelity in postintensive care follow-up consultations at ten sites in the RAPIT-trial: A mixed-methods evaluation
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163
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Biomarker-assisted identification of sepsis-related acute liver impairment: A frequent and deadly condition in critically ill patients
Research output: Contribution to journal › Journal article › Research › peer-review
Published