Søren Brøgger Christensen
Professor emeritus, Professor, emeritus
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Identification and evaluation of Peruvian plants used to treat malaria and leishmaniasis
Kvist, L. P., Christensen, Søren Brøgger, Rasmussen, H. B., Mejia, K. & Gonzalez, Ana Valeria, 19 Jul 2006, In: Journal of Ethnopharmacology. 106, 3, p. 390-402 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hydrophilic carboxylic acids and iridoid glycosides in the juice of American and European cranberries (Vaccinium macrocarpon and V. oxycoccos), lingonberries (V. vitis-idaea), and blueberries (V. myrtillus)
Jensen, H. D., Krogfelt, K. A., Cornett, Claus, Hansen, S. H. & Christensen, Søren Brøgger, 2002, In: Journal of Agricultural and Food Chemistry. 50, 23, p. 6871-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HYDROINDENE SESQUITERPENES FROM THAPSIA-VILLOSA
Smitt, U. W., Cornett, Claus, Norup, E. & Christensen, Søren Brøgger, 1990, In: Phytochemistry. 29, 3, p. 873-875 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Guaianolide Sesquiterpenoids: Pharmacology and biosynthesis
Simonsen, H. T., Weitzel, C. & Christensen, Søren Brøgger, 2013, Natural products: phytochemistry, botany and metabolism of alkaloids, phenolics and terpenes. Ramawat, K. G. & Mérillon, J-M. (eds.). Springer, p. 3069-3098 30 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Fusaric acid and analogues as gram-negative bacterial quorum sensing inhibitors
Thanh Tung, T., Jakobsen, Tim Holm, Dao, T. T., Fuglsang, Anja Thoe, Givskov, Michael, Christensen, Søren Brøgger & Nielsen, J., 2017, In: European Journal of Medicinal Chemistry. 126, p. 1011-1020 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
Christensen, Søren Brøgger, Simonsen, H. T., Engedal, N., Nissen, P., Møller, J. V., Denmeade, S. R. & Isaacs, J. T., 2021, In: Progress in the chemistry of organic natural products. 115, p. 59-114Research output: Contribution to journal › Review › Research › peer-review
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Exciton Coupling in Circular Dichroic Spectroscopy as a Tool for Establishing the Absolute Configuration of alpha,beta-Unsaturated Esters of Allylic Alcohols
Lauridsen, A., Cornett, Claus & Christensen, Søren Brøgger, 1991, In: Acta Chemica Scandinavica. Supplementum. 45, 1, p. 56-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of Medicinal Plants from Chile
Simonsen, H. T., Guzman, A., Adsersen, A., Christensen, Søren Brøgger & Mølgaard, Per, 2008.Research output: Contribution to conference › Conference abstract for conference › Research
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Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy (Science Translational Medicine)
Denmeade, S. R., Mhaka, A. M., Rosen, D. M., Brennen, W. N., Dalrymple, S., Dach, I., Olesen, C., Gurel, B., DeMarzo, A. M., Wilding, G., Carducci, M. A., Dionne, C. A., Møller, J. V., Nissen, Poul, Christensen, Søren Brøgger & Isaacs, J. T., 18 Jul 2012, In: Science Translational Medicine. 4, 143, 143er4.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy
Denmeade, S. R., Mhaka, A. M., Rosen, D. M., Brennen, W. N., Dalrymple, S., Dach, I., Olesen, C., Gurel, B., DeMarzo, A. M., Wilding, G., Carducci, M. A., Dionne, C. A., Møller, J. V., Nissen, P., Christensen, Søren Brøgger & Isaacs, J. T., 27 Jun 2012, In: Science Translational Medicine. 4, 140, p. 140ra86Research output: Contribution to journal › Journal article › Research › peer-review
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Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase
Skytte, D. M., Møller, J. V., Liu, Huizhen, Nielsen, H. Ø., Svenningsen, L. E., Jensen, C. M., Olsen, C. E. & Christensen, Søren Brøgger, 2010, In: Bioorganic & Medicinal Chemistry. 18, 15, p. 5634-5646 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of thapsigargin in isolated rat thoracic aorta
Mikkelsen, E. O., Thastrup, Ole & Christensen, Søren Brøgger, 1988, In: Pharmacology & Toxicology. 62, 1, p. 7-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS
Scharff, O., Foder, B., Thastrup, Ole, Hofmann, B., Møller, J., Ryder, L. P., Jacobsen, K. D., Langhoff, E., Dickmeiss, E. & Christensen, Søren Brøgger, 1988, In: BBA General Subjects. 972, 3, p. 257-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Drugs for the neglected disease malaria based on natural products
Christensen, Søren Brøgger & Bygbjerg, Ib Christian, 1 Jan 2011, Bioactive Compounds from Natural Sources: Natural Products as Lead Compounds in Drug Discovery, Second Edition. CRC Press, p. 525-550 26 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Drugs for the neglected disease malaria based on natural products
Christensen, Søren Brøgger & Bygbjerg, Ib Christian, 2012, Bioactive compounds from natural sources: natural products as lead compounds in drug discovery. Tringali, C. (ed.). 2 ed. Boca Raton: CRC Press, p. 525-550Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Drugs and drug leads based on natural products for treatment and prophylaxis of malaria
Christensen, Søren Brøgger, 25 Feb 2015, Evidence-based validation of herbal medicine: Elsevier. Amsterdam, p. 307-319Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Drugs That Changed Society: Microtubule-Targeting Agents Belonging to Taxanoids, Macrolides and Non-Ribosomal Peptides
Christensen, Søren Brøgger, 2022, In: Molecules. 27, 17, 29 p., 5648.Research output: Contribution to journal › Review › Research › peer-review
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Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams
Christensen, Søren Brøgger, 2021, In: Molecules. 26, 19, 31 p., 6057.Research output: Contribution to journal › Review › Research › peer-review
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Discovery of oxygentade chalcones as novel antimalarial agents
Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, SUPPL. 1, p. S91-S95Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of oxygenated chalcoes as novel antimalarial agents
Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, p. S91-S95 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct difluoromethylation of heterocycles using difluoroacetic acid
Nielsen, J., Truong Thanh Tung & Christensen, Søren Brøgger, 19 Aug 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Dimethyl sulfoxide decreases the fluorescence yield of the reaction between histamine and ortho-phthalaldehyde and may influence histamine release
Moldt, P., Andersen, W. K. & Christensen, Søren Brøgger, 1 Jun 1988, In: Agents and Actions. 24, 1-2, p. 35-39 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds - Scope, Limitations and Perspectives
Nielsen, J., Christensen, Søren Brøgger & Tung, T. T., Dec 2018, In: Synthesis. 50, 23, p. A193-A196 4 p.Research output: Contribution to journal › Conference article › Research › peer-review
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Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds
Thanh Tung, T., Christensen, Søren Brøgger & Nielsen, J., 11 Oct 2017, In: Chemistry: A European Journal. 23, p. 18125-18128Research output: Contribution to journal › Journal article › Research › peer-review
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Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells: complex regulation by intracellular calcium
Christensen, Søren Brøgger, Dubois, C., Abeele, F. V., Sehgal, P., Olesen, C., Junker, S., Prevarskaya, N. & Møller, J. V., 2013, In: F E B S Journal. 280, 21, p. 5430-5440 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1300951
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The antiparasitic compound Licochalcon A is a potent echinocytogenic agent that modifies erythrocyte membrane in the concentration region where the antiplasmodial activity is observed
Research output: Contribution to journal › Journal article › Research › peer-review
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Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae
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Demethoxycurcumin is a potent inhibitor of P-type ATPases from diverse kingdoms of life
Research output: Contribution to journal › Journal article › Research › peer-review
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