Jens Bukh
Professor
Virology
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-13-84
Member of:
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Virus adaptation and selection following challenge of animals vaccinated against classical swine fever virus
Fahnøe, Ulrik, Pedersen, A. G., Johnston, C. M., Orton, R. J., Höper, D., Beer, M., Bukh, Jens, Belsham, Graham John & Rasmussen, T. B., 2019, In: Viruses. 11, 10, 932.Research output: Contribution to journal › Journal article › Research › peer-review
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Viral hepatitis: Cell-culture-derived HCV--a promising vaccine antigen
Gottwein, Judith Margarete & Bukh, Jens, Sep 2013, In: Nature Reviews. Gastroenterology & Hepatology. 10, 9, p. 508-9 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure
STOP-HCV Consortium, S. C., 2021, In: Nature Communications. 12, 1, 11 p., 6105.Research output: Contribution to journal › Journal article › Research › peer-review
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Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication
Fahnøe, Ulrik, Pham, Long, Fernandez-Antunez, C., Costa, Rui, Rivera, Lizandro, Galli, Andrea, Feng, S., Mikkelsen, L. S., Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay & Bukh, Jens, 2022, In: Viruses. 14, 2, 172.Research output: Contribution to journal › Journal article › Research › peer-review
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Vaccines against hepatitis C: A travel into neutralisation space
Bukh, Jens, 2021, In: Gut. 70, 9, p. 1609-1610 2 p., 323377.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus
Meunier, J., Gottwein, J. M., Houghton, M., Russell, R. S., Emerson, S. U., Bukh, Jens & Purcell, R. H., 2011, In: Journal of Infectious Diseases. 204, 8, p. 1186-90 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers
Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Sørensen, Andreas Holst Holmegaard, Jørgensen, T., Clemmensen, S., Soroka, V., Thrane, Susan, Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Bukh, Jens & Sander, Adam F. , 2022, In: npj Vaccines. 7, 148.Research output: Contribution to journal › Journal article › Research › peer-review
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Transmission of clonal hepatitis C virus genomes reveals the dominant but transitory role of CD8¿ T cells in early viral evolution
Callendret, B., Bukh, Jens, Eccleston, H. B., Heksch, R., Hasselschwert, D. L., Purcell, R. H., Hughes, A. L. & Walker, C. M., 2011, In: Journal of Virology. 85, 22, p. 11833-45 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transfusion-associated hepatitis before the screening of blood for hepatitis risk factors
Engle, R. E., Bukh, Jens, Alter, H. J., Emerson, S. U., Trenbeath, J. L., Nguyen, H. T., Brockington, A., Mitra, T. & Purcell, R. H., Nov 2014, In: Transfusion. 54, 11, p. 2833-41 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Toward a vaccine against hepatitis C virus
Offersgaard, Anna Falden, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Science. 380, 6640, p. 37-38 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The history of hepatitis C virus (HCV): Basic research reveals unique features in phylogeny, evolution and the viral life cycle with new perspectives for epidemic control
Bukh, Jens, Oct 2016, In: Journal of Hepatology. 65, 1 Suppl., p. S2-S21Research output: Contribution to journal › Review › Research › peer-review
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The Role of CTLA-4 in T Cell Exhaustion in Chronic Hepatitis B Virus Infection
Apol, Á. D., Winckelmann, Anni Assing, Duus, R. B., Bukh, Jens & Weis, Nina, 2023, In: Viruses. 15, 5, 1141.Research output: Contribution to journal › Review › Research › peer-review
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The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae
Stapleton, J. T., Foung, S., Muerhoff, A. S., Bukh, Jens & Simmonds, P., 2011, In: Journal of General Virology. 92, Pt 2, p. 233-46 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Substitutions in SARS-CoV-2 Mpro Selected by Protease Inhibitor Boceprevir Confer Resistance to Nirmatrelvir
Gammeltoft, Karen Anbro, Zhou, Y., Ryberg, Line Abildgaard, Pham, Long, Binderup, A., Duarte Hernandez, Carlos Rene, Offersgaard, Anna Falden, Fahnøe, Ulrik, Peters, G. H. J., Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Viruses. 15, 9, 17 p., 1970.Research output: Contribution to journal › Journal article › Research › peer-review
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Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance
Jensen, S. B., Serre, S. B. N., Humes, D. G., Ramirez Almeida, Santseharay, Li, Y., Bukh, Jens & Gottwein, Judith Margarete, Dec 2015, In: Antimicrobial Agents and Chemotherapy. 59, 12, p. 7426-7436 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specific antibodies induced by immunization with hepatitis B virus-like particles carrying hepatitis C virus envelope glycoprotein 2 epitopes show differential neutralization efficiency
Czarnota, A., Offersgaard, A., Pihl, A. F., Prentø, Jannick, Bukh, Jens, Gottwein, Judith Margarete, Bieńkowska-Szewczyk, K. & Grzyb, K., 2020, In: Vaccines. 8, 2, 19 p., 294.Research output: Contribution to journal › Journal article › Research › peer-review
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Sars-cov-2 production in a scalable high cell density bioreactor
Offersgaard, Anna Falden, Hernandez, C. R. D., Pihl, A. F., Costa, Rui, Venkatesan, N. P., Lin, X., Pham, Long, Feng, S., Fahnøe, Ulrik, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Reichl, U., Bukh, Jens, Genzel, Y. & Gottwein, Judith Margarete, 2021, In: Vaccines. 9, 7, 706.Research output: Contribution to journal › Journal article › Research › peer-review
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SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination
Castruita, J. A. S., Schneider, Uffe Vest, Mollerup, S., Leineweber, T. D., Weis, Nina, Bukh, Jens, Pedersen, M. S. & Westh, Henrik T., 2023, In: APMIS. 131, 3, p. 128-132 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses
Christensen, D., Polacek, C., Sheward, D. J., Hanke, L., McInerney, G., Murrell, B., Hartmann, Katrine Top, Jensen, Henrik Elvang, Zimmermann, J., Jungersen, G., Illigen, K. E., Isling, L. K., Fernandez-Antunez, C., Ramirez Almeida, Santseharay, Bukh, Jens & Pedersen, Gabriel Kristian, 2023, In: Frontiers in Immunology. 14, 941281.Research output: Contribution to journal › Journal article › Research › peer-review
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Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses
Gottwein, J. M., Scheel, Troels Kasper Høyer, Hoegh, A. M., Lademann, J. B., Eugen-Olsen, J., Lisby, G. & Bukh, Jens, 2007, In: Gastroenterology. 133, 5, p. 1614-26 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains
Li, Y., Ramirez, S., Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Mikkelsen, L., Purcell, R. H. & Bukh, Jens, 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 18, p. E1101-E1110 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir
Ramirez Almeida, Santseharay, Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, Nov 2016, In: Gastroenterology. 151, 5, p. 973-985.e2Research output: Contribution to journal › Journal article › Research › peer-review
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Ribavirin-induced mutagenesis across the complete open reading frame of hepatitis C virus genotypes 1a and 3a
Mejer, N., Fahnøe, Ulrik, Galli, Andrea, Ramirez Almeida, Santseharay, Benfield, Thomas & Bukh, Jens, 2018, In: Journal of General Virology. 99, 8, p. 1066-1077 12 p., 001095.Research output: Contribution to journal › Journal article › Research › peer-review
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Ribavirin inhibition of cell-culture infectious hepatitis C genotype 1-3 viruses is strain-dependent
Mejer, N., Galli, Andrea, Ramirez Almeida, Santseharay, Fahnøe, Ulrik, Benfield, Thomas & Bukh, Jens, 2020, In: Virology. 540, p. 132-140 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells
Wolfisberg, R., Holmbeck, Kenn, Nielsen, L., Kapoor, A., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2019, In: Journal of Virology. 93, 19, 19 p., e00733-19.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12437
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418
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Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies
Research output: Contribution to journal › Review › Research › peer-review
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385
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Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies
Research output: Contribution to journal › Journal article › Research › peer-review
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347
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Hypervariable Region 1 in Envelope Protein 2 of Hepatitis C Virus: A Linchpin in Neutralizing Antibody Evasion and Viral Entry
Research output: Contribution to journal › Review › Research › peer-review
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