Anne Tybjærg-Hansen
Clinical Professor
- 2018
- Published
Response to: liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease
Stender, S. & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 36, p. 3399Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies
Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 2018, In: European Heart Journal. 39, 14, p. 1181-1190 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genetic Variation in GSTP1, Lung Function, Risk of Lung Cancer, and Mortality
Nørskov, M. S., Dahl, Morten & Tybjærg-Hansen, Anne, Nov 2017, In: Journal of Thoracic Oncology. 12, 11, p. 1664-1672 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 31 others, , Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of APOE ε Genotype on Lipoprotein(a) and the Associated Risk of Myocardial Infarction and Aortic Valve Stenosis
Kritharides, L., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Kamstrup, P. R. & Afzal, Shoaib, 1 Sep 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 9, p. 3390-3399 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body mass index and risk of Alzheimer's disease: A mendelian randomization study of 399,536 individuals
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jul 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 7, p. 2310-2320 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
Dewey, F. E., Gusarova, V., Dunbar, R. L., O'Dushlaine, C. T., Schurmann, C., Gottesman, O., McCarthy, S., Van Hout, C. V., Bruse, S., Dansky, H. M., Leader, J. B., Murray, M. F., Ritchie, M. D., Kirchner, H. L., Habegger, L., Lopez, A., Penn, J., Zhao, A., Shao, W., Stahl, N. & 37 others, , Jul 2017, In: New England Journal of Medicine. 377, 3, p. 211-221Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits
Tachmazidou, I., Süveges, D., Min, J. L., Ritchie, G. R. S., Steinberg, J., Walter, K., Iotchkova, V., Schwartzentruber, J., Huang, J., Memari, Y., McCarthy, S., Crawford, A. J., Bombieri, C., Cocca, M., Farmaki, A-E., Gaunt, T. R., Jousilahti, P., Kooijman, M. N., Lehne, B., Malerba, G. & 31 others, , 1 Jun 2017, In: American Journal of Human Genetics. 100, 6, p. 865-884 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
Stender, S., Kozlitina, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Hobbs, H. H. & Cohen, J. C., Jun 2017, In: Nature Genetics. 49, 6, p. 842-847 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study
Benn, Marianne, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 24 Apr 2017, In: B M J. 357, 11 p., j1648.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in WRN and ischemic stroke: General population studies and meta-analyses
Christoffersen, M., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Mar 2017, In: Experimental Gerontology. 89, p. 69-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare and low-frequency coding variants alter human adult height
Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, , 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood Chimerism in Dizygotic Monochorionic Twins During 5 Years Observation
Dziegiel, Morten Hanefeld, Hansen, M. H., Haedersdal, S., Barrett, A. N., Rieneck, K., Main, Katharina Maria, Tybjærg-Hansen, Anne & Clausen, F. B., 2017, In: American Journal of Transplantation. 17, 10, p. 2728-2732Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Howson, J. M. M., Zhao, W., Barnes, D. R., Ho, W. K., Young, R., Paul, D. S., Waite, L., Freitag, D. F., Fauman, E. B., Salfati, E. L., Sun, B. B., Eicher, J. D., Johnson, A. D., Sheu, W. H-H., Nielsen, S. F., Lin, W-Y., Surendran, P., Malarstig, A., Wilk, J. B., Tybjærg-Hansen, A. & 36 others, , 2017, In: Nature Genetics. 49, p. 1113-1119Research output: Contribution to journal › Letter › Research › peer-review
- Published
Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer
Kobberø Lauridsen, B., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2017, In: International Journal of Epidemiology. 46, 6, p. 1777-1785Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Using Human Genetics to Predict the Effects and Side Effects of Lipoprotein(a) Lowering Drugs
Tybjærg-Hansen, Anne, Dec 2016, In: Journal of the American College of Cardiology. 68, 25, p. 2773-2775 3 p.Research output: Contribution to journal › Comment/debate › Research
- Published
SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)
Yang, X., Sethi, A. A., Yanek, L. R., Knapper, C., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Becker, D. M., Mathias, R. A., Remaley, A. T. & Becker, L. C., Oct 2016, In: Circulation: Cardiovascular Genetics. 9, 5, p. 408-418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BODY MASS INDEX AND MORTALITY OVER 3 DECADES
Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, Sep 2016, In: Atherosclerosis. 252, p. E222-E222 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High body mass index and cancer risk
Benn, Marianne, Tybjærg-Hansen, Anne, Smith, G. D. & Nordestgaard, Børge, Sep 2016, In: European Journal of Epidemiology. 31, 9, p. 879-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein(a) and familial hypercholesterolaemia - Authors' reply
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Sep 2016, In: The Lancet Diabetes and Endocrinology. 4, 9, p. 730-731 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
PCSK9 R46L Loss-of-Function Mutation Reduces Lipoprotein(a), LDL Cholesterol, and Risk of Aortic Valve Stenosis
Langsted, A., Nordestgaard, Børge, Benn, Marianne, Tybjærg-Hansen, Anne & Kamstrup, P. R., Sep 2016, In: The Journal of clinical endocrinology and metabolism. 101, 9, p. 3281-3287 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Components of the Metabolic Syndrome and Risk of Type 2 Diabetes
Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Aug 2016, In: The Journal of clinical endocrinology and metabolism. 101, 8, p. 3212-3221 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies
Joshi, A. D., Andersson, C., Buch, S., Stender, S., Noordam, R., Weng, L-C., Weeke, P. E., Auer, P. L., Boehm, B., Chen, C., Choi, H., Curhan, G., Denny, J. C., De Vivo, I., Eicher, J. D., Ellinghaus, D., Folsom, A. R., Fuchs, C., Gala, M., Haessler, J. & 35 others, , Aug 2016, In: Gastroenterology. 151, 2, 351 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High lipoprotein(a) as a possible cause of clinical familial hypercholesterolaemia: a prospective cohort study
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jul 2016, In: The Lancet Diabetes and Endocrinology. 4, 7, p. 577-587 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Sialylation Pathway and Coronary Artery Disease
Tybjærg-Hansen, Anne, 2 Jun 2016, In: New England Journal of Medicine. 374, 22, p. 2169-2171 3 p.Research output: Contribution to journal › Editorial › Research
- Published
Change in Body Mass Index Associated With Lowest Mortality in Denmark, 1976-2013
Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, 10 May 2016, In: JAMA - Journal of the American Medical Association. 315, 18, p. 1989-1996 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217
Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plakophilin-2 c.419C>T and risk of heart failure and arrhythmias in the general population
Christensen, A. H., Kamstrup, P. R., Gandjbakhch, E., Benn, Marianne, Jensen, J. S., Bundgård, Henning, Villard, E. & Tybjærg-Hansen, Anne, May 2016, In: European Journal of Human Genetics. 24, 5, p. 732-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using human genetics to predict the effects and side-effects of drugs
Stender, S. & Tybjærg-Hansen, Anne, Apr 2016, In: Current Opinion in Lipidology. 27, 2, p. 105-111 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
CHD Exome+ Consortium, C. E. C., CARDIoGRAM Exome Consortium, C. E. C. & Global Lipids Genetics Consortium, G. L. G. C., 11 Mar 2016, In: Science (New York, N.Y.). 351, 6278, p. 1166-71 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Data in Brief. 6, p. 923-932 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of apolipoprotein E and risk of ischemic heart disease in the general population
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Atherosclerosis. 246, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of Coronary Artery Disease
McPherson, R. & Tybjærg-Hansen, Anne, 18 Feb 2016, In: Circulation Research. 118, 4, p. 564-578 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Baseline C-Reactive Protein Concentrations Are Associated with Increased Risk of Infections: Results from 2 Large Danish Population Cohorts
Zacho, J., Benfield, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2016, In: Clinical Chemistry. 62, 2, p. 335-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to the Letter: Response to "Use of biomarkers to identify new drug targets and to predict risk of cardiometabolic outcomes" by Abasi A., et al
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Feb 2016, In: The Journal of clinical endocrinology and metabolism. 101, 2, p. L22-L23Research output: Contribution to journal › Letter › Research › peer-review
- Published
Sex Hormones and Ischemic Stroke: A Prospective Cohort Study and Meta-Analyses
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Jan 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 1, p. 69-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visible aging signs as risk markers for ischemic heart disease: Epidemiology, pathogenesis and clinical implications
Christoffersen, M. & Tybjærg-Hansen, Anne, Jan 2016, In: Ageing Research Reviews. 25, p. 24-41 18 p.Research output: Contribution to journal › Review › Research › peer-review
- 2015
- Published
Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Dec 2015, In: Alzheimer's & Dementia. 11, 12, p. 1430-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment
Wiegman, A., Gidding, S. S., Watts, G. F., Chapman, M. J., Ginsberg, H. N., Cuchel, M., Ose, L., Averna, M., Boileau, C., Borén, J., Bruckert, E., Catapano, A. L., Defesche, J. C., Descamps, O. S., Hegele, R. A., Hovingh, G. K., Humphries, S. E., Kovanen, P. T., Kuivenhoven, J. A., Masana, L. & 13 others, , 21 Sep 2015, In: European Heart Journal. 36, 36, p. 2425-37 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variation in NPC1L1 and Risk of Gallstone Disease
Lauridsen, B. K., Stender, S. & Tybjærg-Hansen, Anne, 1 Sep 2015, In: Journal of the American College of Cardiology. 66, 9, p. 1086 1 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
HDL Cholesterol and Risk of Type 2 Diabetes: A Mendelian Randomization Study
Haase, C. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Sep 2015, In: Diabetes. 64, 9, p. 3328-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease
Lauridsen, B. K., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Jul 2015, In: European Heart Journal. 36, 25, p. 1601-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel genes in LDL metabolism: a comprehensive overview
Christoffersen, M. & Tybjærg-Hansen, Anne, Jun 2015, In: Current Opinion in Lipidology. 26, 3, p. 179-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
Do, R., Stitziel, N. O., Won, H-H., Jørgensen, A. B., Duga, S., Angelica Merlini, P., Kiezun, A., Farrall, M., Goel, A., Zuk, O., Guella, I., Asselta, R., Lange, L. A., Peloso, G. M., Auer, P. L., Girelli, D., Martinelli, N., Farlow, D. N., DePristo, M. A., Roberts, R. & 31 others, , 5 Feb 2015, In: Nature. 518, 7537, p. 102-6, 4 unpag. pages 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Extreme concentrations of endogenous sex hormones, ischemic heart disease, and death in women
Benn, Marianne, Voss, S. S., Holmegard, H. N., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2 Feb 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 2, p. 471-477 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of apolipoprotein E and risk of dementia in the general population
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Feb 2015, In: Annals of Neurology. 77, 2, p. 301-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Blood Pressure as Mediators From Obesity to Ischemic Heart Disease
Varbo, A., Benn, Marianne, Smith, G. D., Timpson, N. J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2015, In: Circulation Research. 116, 4, p. 665-673 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J. & 113 others, , 24 Jan 2015, In: Lancet. 385, 9965, p. 351-361 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Huang, J., Howie, B., Mccarthy, S., Memari, Y., Walter, K., Min, J. L., Danecek, P., Malerba, G., Trabetti, E., Zheng, H., Al Turki, S., Amuzu, A., Anderson, C. A., Anney, R., Antony, D., Artigas, M. S., Ayub, M., Bala, S., Barrett, J. C., Barroso, I. & 219 others, , 2015, In: Nature Communications. 6, 9 p., 8111.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
Research output: Contribution to journal › Journal article › Research › peer-review
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256
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The UK10K project identifies rare variants in health and disease
Research output: Contribution to journal › Journal article › Research › peer-review
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Research output: Contribution to journal › Journal article › Research › peer-review
Published