Cord Herbert Brakebusch
Department of Biomedical Sciences
Blegdamsvej 3
2200 København N
- 2008
- Published
Rac1 is essential for phospholipase C-gamma2 activation in platelets.
Pleines, I., Elvers, M., Strehl, A., Pozgajova, M., Varga-Szabo, D., May, F., Chrostek-Grashoff, A., Brakebusch, Cord Herbert & Nieswandt, B., 2008, In: Pflügers Archiv: European Journal of Physiology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver.
van Hengel, J., D'Hooge, P., Hooghe, B., Wu, X., Libbrecht, L., De Vos, R., Quondamatteo, F., Klempt, M., Brakebusch, Cord Herbert & van Roy, F., 2008, In: Gastroenterology. 134, 3, p. 781-92 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development.
Benninger, Y., Thurnherr, T., Pereira, J. A., Krause, S., Wu, X., Chrostek-Grashoff, A., Herzog, D., Nave, K., Franklin, R. J. M., Meijer, D., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2007, In: Journal of Cell Biology. 177, 6, p. 1051-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose? (vol 14, pg 70, 2005)
Boehncke, W. H., Schon, M. P., Giromolomi, G., Griffiths, C., Bos, J. D., Thestrup-Pedersen, K., Cavani, A., Nestle, F., Bonish, B. K., Campbell, J. J., Brakebusch, Cord Herbert & Nickoloff, B., 2007, In: Experimental Dermatology. 16, 9, p. 778-778Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways.
Bosse, T., Ehinger, J., Czuchra, A., Benesch, S., Steffen, A., Wu, X., Schloen, K., Niemann, H. H., Scita, G., Stradal, T. E. B., Brakebusch, Cord Herbert & Rottner, K., 2007, In: Molecular and Cellular Biology. 27, 19, p. 6615-28 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cdc42 regulates cofilin during the establishment of neuronal polarity.
Garvalov, B. K., Flynn, K. C., Neukirchen, D., Meyn, L., Teusch, N., Wu, X., Brakebusch, Cord Herbert, Bamburg, J. R. & Bradke, F., 2007, In: Journal of Neuroscience. 27, 48, p. 13117-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1.
Tscharntke, M., Pofahl, R., Chrostek-Grashoff, A., Smyth, N., Niessen, C., Niemann, C., Hartwig, B., Herzog, V., Klein, H. W., Krieg, T., Brakebusch, Cord Herbert & Haase, I., 2007, In: Journal of Cell Science. 120, Pt 8, p. 1480-90 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development.
Wu, X., Li, S., Chrostek-Grashoff, A., Czuchra, A., Meyer, H., Yurchenco, P. D. & Brakebusch, Cord Herbert, 2007, In: Developmental Dynamics. 236, 10, p. 2767-78 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Lack of beta1 integrins in enteric neural crest cells leads to a Hirschsprung-like phenotype.
Breau, M. A., Pietri, T., Eder, O., Blanche, M., Brakebusch, Cord Herbert, Fässler, R., Thiery, J. P. & Dufour, S., 2006, In: Development. 133, 9, p. 1725-34 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adult murine hematopoiesis can proceed without beta1 and beta7 integrins.
Bungartz, G., Stiller, S., Bauer, M., Müller, W., Schippers, A., Wagner, N., Fässler, R. & Brakebusch, Cord Herbert, 2006, In: Blood. 108, 6, p. 1857-64 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.
Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch-Bräuninger, M., Eilken, H. M., Rieger, M. A., Schroeder, T. T., Huttner, W. B., Brakebusch, Cord Herbert & Götz, M., 2006, In: Nature Neuroscience. 9, 9, p. 1099-107 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis.
Chrostek, A., Wu, X., Quondamatteo, F., Hu, R., Sanecka, A., Niemann, C., Langbein, L., Haase, I. & Brakebusch, Cord Herbert, 2006, In: Molecular and Cellular Biology. 26, 18, p. 6957-70 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury.
Cordes, N., Seidler, J., Durzok, R., Geinitz, H. & Brakebusch, Cord Herbert, 2006, In: Oncogene. 25, 9, p. 1378-90 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic analysis of beta1 integrin "activation motifs" in mice.
Czuchra, A., Meyer, H., Legate, K. R., Brakebusch, Cord Herbert & Fässler, R., 2006, In: Journal of Cell Biology. 174, 6, p. 889-99 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RhoH is important for positive thymocyte selection and T-cell receptor signaling.
Dorn, T., Kuhn, U., Bungartz, G., Stiller, S., Bauer, M., Ellwart, J., Peters, T., Scharffetter-Kochanek, K., Semmrich, M., Laschinger, M., Holzmann, B., Klinkert, W. E. F., Straten, P. T., Køllgaard, T., Sixt, M. & Brakebusch, Cord Herbert, 2006, In: Blood. 109, 6, p. 2346-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Threonine 788 in integrin subunit beta1 regulates integrin activation.
Nilsson, S., Kaniowska, D., Brakebusch, Cord Herbert, Fässler, R. & Johansson, S., 2006, In: Experimental Cell Research. 312, 6, p. 844-53 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS.
Thurnherr, T., Benninger, Y., Wu, X., Chrostek, A., Krause, S. M., Nave, K., Franklin, R. J. M., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2006, In: Journal of Neuroscience. 26, 40, p. 10110-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin.
Wu, X., Quondamatteo, F., Lefever, T., Czuchra, A., Meyer, H., Chrostek, A., Paus, R., Langbein, L. & Brakebusch, Cord Herbert, 2006, In: Genes & Development. 20, 5, p. 571-85 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cdc42 expression in keratinocytes is required for the maintenance of the basement membrane in skin.
Wu, X., Quondamatteo, F. & Brakebusch, Cord Herbert, 2006, In: Matrix Biology. 25, 8, p. 466-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose?
Boehncke, W., Schön, M. P., Girolomoni, G., Giromolomi, G., Griffiths, C., Bos, J. D., Thestrup-Pedersen, K., Cavani, A., Nestle, F., Bonish, B. K., Campbell, J. J., Brakebusch, Cord Herbert & Nickoloff, B., 2005, In: Experimental Dermatology. 14, 1, p. 70-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
beta 1 integrin function in vivo: adhesion, migration and more.
Brakebusch, Cord Herbert & Fässler, R., 2005, In: Cancer Metastasis Review. 24, 3, p. 403-11 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Integrin blockade as therapy in chronic inflammation
Brakebusch, Cord Herbert, 1 May 2005, In: Experimental Dermatology. 14, 5, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
Keratinocyte Migration in Wound Healing
Brakebusch, Cord Herbert, 9 Aug 2005, Cell Migration in Development and Disease. Wiley-VCH Verlag GmbH & Co. KGaA, p. 275-298 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells.
Czuchra, A., Wu, X., Meyer, H., van Hengel, J., Schroeder, T., Geffers, R., Rottner, K. & Brakebusch, Cord Herbert, 2005, In: Molecular Biology of the Cell. 16, 10, p. 4473-84 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of neural progenitor proliferation and survival by beta1 integrins.
Leone, D. P., Relvas, J. B., Campos, L. S., Hemmi, S., Brakebusch, Cord Herbert, Fässler, R., Ffrench-Constant, C. & Suter, U., 2005, In: Journal of Cell Science. 118, Pt 12, p. 2589-99 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency
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207
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Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
198
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The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells
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