Anne-Vibeke Lænkholm
Clinical Associate Professor
- 2018
- Published
Clinical and molecular characterization of BRCA-associated breast cancer: results from the DBCG
Soenderstrup, I. M. H., Lænkholm, Anne-Vibeke, Jensen, M. B., Eriksen, J. O., Gerdes, Anne-Marie Axø, Hansen, T. V. O., Kruse, T. A., Larsen, M. J., Pedersen, I. S., Rossing, M., Thomassen, M. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 95-101Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Standardized assessment of tumor-infiltrating lymphocytes in breast cancer: an evaluation of inter-observer agreement between pathologists
Tramm, T., Di Caterino, T., Jylling, A. M. B., Lelkaitis, G., Lænkholm, Anne-Vibeke, Ragó, P., Tabor, T. P., Talman, M. L. M., Vouza, E. & On behalf of the Scientific Committee of Pathology, Danish Breast Cancer Group (DBCG), O. B. O. T. S. C. O. P. D. B. C. G. (., 2018, In: Acta Oncologica. 57, 1, p. 90-94Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Application of automated image analysis reduces the workload of manual screening of sentinel lymph node biopsies in breast cancer
Holten-Rossing, H., Talman, M. M., Jylling, A. M. B., Lænkholm, Anne-Vibeke, Kristensson, M. & Vainer, B., Dec 2017, In: Histopathology. 71, 6, p. 866-873Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence
Krøigård, A. B., Larsen, M. J., Brasch-Andersen, C., Lænkholm, Anne-Vibeke, Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Thomassen, M. & Kruse, T. A., 2017, In: Scientific Reports. 7, 9 p., 43813.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., ABCTB Investigators, Adams, M., Adlard, J. & 27 others, , 2017, In: Nature Genetics. 49, 12, p. 1767-1778Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Prognostic impact of tumor MET expression among patients with stage IV gastric cancer: a Danish cohort study
Erichsen, R., Kelsh, M. A., Oliner, K. S., Nielsen, K. B., Frøslev, T., Lænkholm, Anne-Vibeke, Vyberg, M., Acquavella, J. & Sørensen, H. T., Jul 2016, In: Annals of Epidemiology. 26, 7, p. 500-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of prediction of local recurrence (LR) by Prosigna® (PAM50) in a Danish breast cancer cooperative group (DBCG) cohort of hormone receptor positive (HR+), postmenopausal early breast cancer (EBC) patients allocated to 5yr of endocrine therapy (ET)
Eriksen, J. O., Jensen, M., Lænkholm, Anne-Vibeke, Kibøll, T., Rasmussen, B. B., Knoop, A. S., Ferree, S., Haffner, T., Buckingham, W., Schaper, C. & Ejlertsen, B., 2016, In: Cancer Research. 76, 4 Supplement, 1 p., P2-08-10.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Evaluation of Nine Somatic Variant Callers for Detection of Somatic Mutations in Exome and Targeted Deep Sequencing Data
Krøigård, A. B., Thomassen, M., Lænkholm, Anne-Vibeke, Kruse, T. A. & Larsen, M. J., 2016, In: PloS one. 11, 3, 15 p., e0151664.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration
Leung, S. C. Y., Nielsen, T. O., Zabaglo, L., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Enos, R. A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A-V. & 14 others, , 2016, In: npj Breast Cancer. 2, p. 16014Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Gene expression profiling identifies FYN as an important molecule in tamoxifen resistance and a predictor of early recurrence in patients treated with endocrine therapy
Elias, D., Vever, H., Lænkholm, Anne-Vibeke, Gjerstorff, M. F., Yde, C. W., Lykkesfeldt, A. E. & Ditzel, H. J., 9 Apr 2015, In: Oncogene. 34, 15, p. 1919-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis
Krøigård, A. B., Larsen, M. J., Lænkholm, Anne-Vibeke, Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Kruse, T. A. & Thomassen, M., 2015, In: OncoTarget. 6, 8, p. 5634-49 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer
Larsen, S. L., Yde, C. W., Lænkholm, Anne-Vibeke, Rasmussen, B. B., Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 8 Apr 2015, In: B M C Cancer. 15, 15 p., 239.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment
Larsen, S. L., Lænkholm, Anne-Vibeke, Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 2015, In: PloS one. 10, 2, e0118346.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NADH-Cytochrome b5 Reductase 3 Promotes Colonization and Metastasis Formation and Is a Prognostic Marker of Disease-Free and Overall Survival in Estrogen Receptor-Negative Breast Cancer
Lund, R. R., Leth-Larsen, R., Caterino, T. D., Terp, M. G., Nissen, J., Lænkholm, Anne-Vibeke, Jensen, O. N. & Ditzel, H. J., Nov 2015, In: Molecular and Cellular Proteomics. 14, 11, p. 2988-99 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An international study to increase concordance in Ki67 scoring
Polley, M-Y. C., Leung, S. C. Y., Gao, D., Mastropasqua, M. G., Zabaglo, L. A., Bartlett, J. M. S., McShane, L. M., Enos, R. A., Badve, S. S., Bane, A. L., Borgquist, S., Fineberg, S., Lin, M-G., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Moriya, T., Ohi, Y., Osborne, C. K. & 11 others, , 2015, In: Modern Pathology. 28, 6, p. 778-86 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression alterations associated with outcome in aromatase inhibitor-treated ER+ early-stage breast cancer patients
Thomsen, K. G., Lyng, M. B., Elias, D., Vever, H., Knoop, A. S., Lykkesfeldt, A. E., Lænkholm, Anne-Vibeke & Ditzel, H. J., Dec 2015, In: Breast Cancer Research and Treatment. 154, 3, p. 483-94 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells
Thrane, Susan, Pedersen, A. M., Thomsen, M. B. H., Kirkegaard, T., Rasmussen, B. B., Duun-Henriksen, A. K., Lænkholm, Anne-Vibeke, Bak, M., Lykkesfeldt, A. E. & Yde, C. W., 6 Aug 2015, In: Oncogene. 34, 32, p. 4199-210 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Estrogen receptor, Progesterone receptor, HER2 status and Ki67 index and responsiveness to adjuvant tamoxifen in postmenopausal high-risk breast cancer patients enrolled in the DBCG 77C trial
Knoop, A. S., Lænkholm, Anne-Vibeke, Jensen, M., Nielsen, K. V., Andersen, J., Nielsen, D., Ejlertsen, B. & Danish Breast Cancer Cooperative Group, D. B. C. C. G., 2014, In: European journal of cancer (Oxford, England : 1990). 50, 8, p. 1412-1421 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA profiling reveals familial aggregation of molecular subtypes in non-BRCA1/2 breast cancer families
Larsen, M. J., Thomassen, M., Tan, Q., Lænkholm, Anne-Vibeke, Bak, M., Sørensen, K. P., Andersen, M. K., Kruse, T. A. & Gerdes, Anne-Marie Axø, 2014, In: B M C Medical Genomics. 7, p. 9Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling
Larsen, M. J., Kruse, T. A., Tan, Q., Lænkholm, Anne-Vibeke, Bak, M., Lykkesfeldt, A. E., Sørensen, K. P., Hansen, Thomas van Overeem, Ejlertsen, Bent Laursen, Gerdes, Anne-Marie Axø & Thomassen, M., 2013, In: P L o S One. 8, 5, 12 p., e64268.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression signatures that predict outcome of tamoxifen-treated estrogen receptor-positive, high-risk, primary breast cancer patients: a DBCG study
Lyng, M. B., Lænkholm, Anne-Vibeke, Tan, Q., Vach, W., Gravgaard, K. H., Knoop, A. & Ditzel, H., 2013, In: PLOS ONE. 8, 1, p. e54078Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
PIK3CA mutations, PTEN, and pHER2 expression and impact on outcome in HER2-positive early-stage breast cancer patients treated with adjuvant chemotherapy and trastuzumab
Jensen, J. D., Knoop, A., Lænkholm, Anne-Vibeke, Grauslund, M., Jensen, M. B., Santoni Rugiu, Eric, Andersson, M. & Ewertz, M., Aug 2012, In: Annals of oncology : official journal of the European Society for Medical Oncology. 23, 8, p. 2034-2042 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ER, HER2, and TOP2A expression in primary tumor, synchronous axillary nodes, and asynchronous metastases in breast cancer
Jensen, J. D., Knoop, A., Ewertz, M. & Lænkholm, Anne-Vibeke, Apr 2012, In: Breast Cancer Research and Treatment. 132, 2, p. 511-21 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ESR1 gene status correlates with estrogen receptor protein levels measured by ligand binding assay and immunohistochemistry
Lænkholm, Anne-Vibeke, Knoop, A., Ejlertsen, Bent Laursen, Rudbeck, T., Jensen, M., Müller, S., Lykkesfeldt, A. E., Rasmussen, B. B. & Nielsen, K. V., Aug 2012, In: Molecular Oncology. 6, 4, p. 428-36 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy
Larsen, M. S., Bjerre, K., Lykkesfeldt, A. E., Giobbie-Hurder, A., Lænkholm, Anne-Vibeke, Henriksen, K. L., Ejlertsen, Bent Laursen & Rasmussen, B. B., Oct 2012, In: Breast (Edinburgh, Scotland). 21, 5, p. 662-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 102813499
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Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
83
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The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
82
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Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence
Research output: Contribution to journal › Journal article › Research › peer-review
Published