Jens Bukh

Jens Bukh

Professor

Member of:


    1. 2022
    2. Published

      Neutralizing Antibodies Against Hepatitis C Virus and Their Role in Vaccine Immunity

      Bukh, Jens, 2022, In: Gastroenterology. 162, 2, p. 396-398 3 p.

      Research output: Contribution to journalEditorialResearchpeer-review

    3. Published

      At the Core of Depression: A Diagnostic Interview of the Core Features of Depression

      Bukh, Jens, Fabrazzo, M., Christensen, E. M., Mikkelsen, R. L., Larsen, J. K., Hageman, I., Bendsen, B. B., Bolwig, T., Vinberg, Maj, Bech, P., Dam, O. H., Maj, M. & Kessing, Lars Vedel, 11 Mar 2022, In: Psychopathology. 55, 3-4, p. 219–225 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Protection against SARS-CoV-2 transmission by a parenteral prime—Intranasal boost vaccine strategy

      Christensen, D., Polacek, C., Sheward, D. J., Hanke, L., Moliner-morro, A., Mcinerney, G., Murrell, B., Hartmann, Katrine Top, Jensen, Henrik Elvang, Jungersen, G., Illigen, K., Isling, L. K., Jensen, R. F., Hansen, J. S., Rosenkrands, I., Fernandez-antunez, C., Ramirez Almeida, Santseharay, Follmann, F., Bukh, Jens & Pedersen, G. K., 2022, In: EBioMedicine. 84, 104248.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      A distinct dexamethasone-dependent gene expression profile in the lungs of COVID-19 patients

      Fahnøe, Ulrik, Ronit, A., Berg, Ronan Martin Griffin, Jørgensen, S. E., Mogensen, T. H., Underwood, Alexander Paul James, Scheel, Troels Kasper Høyer, Bukh, Jens & Plovsing, R. R., 2022, In: The Journal of Infectious Diseases. 226, 12, p. 2137–2141

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication

      Fahnøe, Ulrik, Pham, Long, Fernandez-Antunez, C., Costa, Rui, Rivera, Lizandro, Galli, Andrea, Feng, S., Mikkelsen, L. S., Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay & Bukh, Jens, 2022, In: Viruses. 14, 2, 172.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      High recombination rate of hepatitis C virus revealed by a green fluorescent protein reconstitution cell system

      Galli, Andrea, Fahnøe, Ulrik & Bukh, Jens, 2022, In: Virus Evolution. 8, 1, veab106.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      High‐Titer Hepatitis C Virus Production in a Scalable Single‐Use High Cell Density Bioreactor

      Offersgaard, Anna Falden, Duarte Hernandez, C. R., Finne Pihl, A., Prabhakar Venkatesan, N., Krarup, H., Lin, X., Reichl, U., Bukh, Jens, Genzel, Y. & Gottwein, Judith Margarete, 2022, In: Vaccines. 10, 2, 249.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals

      Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P., Ramirez Almeida, S. & 4 others, Reichl, U., Genzel, Y., Bukh, Jens & Gottwein, Judith Margarete, 6 Jul 2022.

      Research output: Contribution to conferencePosterCommunication

    10. Published

      HCV genome-wide analysis for development of efficient culture systems and unravelling of antiviral resistance in genotype 4

      Pham, Long, Pedersen, M. S., Fahnøe, Ulrik, Fernandez-Antunez, C., Humes, D., Schønning, Kristian, Ramirez Almeida, Santseharay & Bukh, Jens, 2022, In: Gut. 71, p. 627-642 20323585.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Novel HCV Genotype 4d Infectious Systems and Assessment of Direct-Acting Antivirals and Antibody Neutralization

      Pham, Long, Velázquez-Moctezuma, R., Fahnøe, Ulrik, Collignon, Laura Maria F, Bajpai, P., Sølund, C., Weis, Nina, Holmbeck, Kenn, Prentø, Jannick & Bukh, Jens, 2022, In: Viruses. 14, 11, 2527.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Inactivated whole hepatitis C virus vaccine employing a licensed adjuvant elicits cross-genotype neutralizing antibodies in mice

      Pihl, A. F., Feng, S., Offersgaard, Anna Falden, Alzua, G. P., Augestad, Elias Honerød, Mathiesen, C. K., Jensen, T. B., Krarup, H., Law, M., Prentø, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens & Gottwein, Judith Margarete, 2022, In: Journal of Hepatology. 76, 5, p. 1051-1061

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers

      Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Sørensen, Andreas Holst Holmegaard, Jørgensen, T., Clemmensen, S., Soroka, V., Thrane, Susan, Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Bukh, Jens & Sander, Adam F. , 2022, In: npj Vaccines. 7, 148.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Analysis of Neutralization Titers against SARS-CoV-2 in Health-Care Workers Vaccinated with Prime-Boost mRNA–mRNA or Vector–mRNA COVID-19 Vaccines

      Sølund, C., Underwood, Alexander Paul James, Fernandez-Antunez, C., Bollerup, S., Mikkelsen, L. S., Villadsen, S. L., Fahnøe, Ulrik, Winckelmann, Anni Assing, Feng, S., Nørløv Vinten, C. A., Dalegaard, M. I., Vizgirda, G., Sørensen, A. L., Ramirez Almeida, Santseharay, Bukh, Jens & Weis, Nina, 2022, In: Vaccines. 10, 1, 75.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Novel hepatitis B virus reverse transcriptase mutations in patients with sustained viremia despite long-term tenofovir treatment

      Winckelmann, Anni Assing, Fahnøe, Ulrik, Bajpai, P. S., Dalegaard, M. I., Lundh, A., Ryom, L., Bukh, Jens & Weis, Nina, 2022, In: Journal of Clinical Virology. 150-151, 6 p., 105159.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV

      Wolfisberg, R., Thorselius, Caroline Eva, Salinas, E., Elrod, E., Trivedi, S., Nielsen, L., Fahnøe, Ulrik, Kapoor, A., Grakoui, A., Rice, C. M., Bukh, Jens, Holmbeck, Kenn & Scheel, Troels Kasper Høyer, 2022, In: Hepatology. 76, 5, p. 1506-1519

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Nirmatrelvir-resistant SARS-CoV-2 variants with high fitness in an infectious cell culture system

      Zhou, Y., Gammeltoft, Karen Anbro, Ryberg, Line Abildgaard, Pham, Long, Tjørnelund, H. D., Binderup, A., Duarte Hernandez, Carlos Rene, Fernandez-Antunez, C., Offersgaard, Anna Falden, Fahnøe, Ulrik, Peters, G. H. J., Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2022, In: Science Advances. 8, 51, eadd7197.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. 2021
    19. Published

      Hepatitis C virus envelope protein dynamics and the link to hypervariable region 1

      Augestad, Elias Honerød, Bukh, Jens & Prentø, Jannick, 2021, In: Current Opinion in Virology. 50, p. 69-75 7 p.

      Research output: Contribution to journalReviewResearchpeer-review

    20. Published

      Vaccines against hepatitis C: A travel into neutralisation space

      Bukh, Jens, 2021, In: Gut. 70, 9, p. 1609-1610 2 p., 323377.

      Research output: Contribution to journalComment/debateResearchpeer-review

    21. Published

      Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins

      Chen, F., Tzarum, N., Lin, X., Giang, E., Velázquez-Moctezuma, R., Augestad, Elias Honerød, Nagy, K., He, L., Hernandez, M., Fouch, M. E., Grinyó, A., Chavez, D., Doranz, B. J., Prentø, Jannick, Stanfield, R. L., Lanford, R., Bukh, Jens, Wilson, I. A., Zhu, J. & Law, M., 2021, In: Immunity. 54, 4, p. 781-796.e4

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Global evolutionary analysis of chronic hepatitis C patients revealed significant effect of baseline viral resistance, including novel non-target sites, for DAA-based treatment and retreatment outcome

      Fahnøe, Ulrik, Pedersen, M. S., Sølund, C., Ernst, A., Krarup, H. B., Røge, B. T., Christensen, P. B., Laursen, A. L., Gerstoft, Jan, Thielsen, P., Madsen, Lone Galmstrup, Pedersen, A. G., Schønning, Kristian, Weis, Nina & Bukh, Jens, 2021, In: Journal of Viral Hepatitis. 28, 2, p. 302-316

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published
    24. Published

      Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 in Vitro

      Gammeltoft, Karen Anbro, Zhou, Y., Duarte Hernandez, C. R., Galli, Andrea, Offersgaard, Anna Falden, Costa, Rui, Pham, Long, Fahnøe, Ulrik, Feng, S., Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2021, In: Antimicrobial Agents and Chemotherapy. 65, 9, e02680-20.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      In vitro Characterization of Fitness and Convalescent Antibody Neutralization of SARS-CoV-2 Cluster 5 Variant Emerging in Mink at Danish Farms

      Lassaunière, R., Fonager, J., Rasmussen, M., Frische, A., Polacek, C., Rasmussen, T. B., Lohse, L., Belsham, Graham John, Underwood, Alexander Paul James, Winckelmann, A. A., Bollerup, S., Bukh, Jens, Weis, Nina, Sækmose, S. G., Aagaard, B., Alfaro-Núñez, A., Mølbak, Kåre, Bøtner, A. & Fomsgaard, A., 2021, In: Frontiers in Microbiology. 12, 9 p., 698944.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Inferior cure rate in pilot study of 4-week glecaprevir/pibrentasvir treatment with or without ribavirin of chronic hepatitis C

      Madsen, L. W., Christensen, P. B., Fahnøe, Ulrik, Pedersen, M. S., Bukh, Jens & Øvrehus, A., 2021, In: Liver International. 41, 11, p. 2601-2610

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Sars-cov-2 production in a scalable high cell density bioreactor

      Offersgaard, Anna Falden, Hernandez, C. R. D., Pihl, A. F., Costa, Rui, Venkatesan, N. P., Lin, X., Pham, Long, Feng, S., Fahnøe, Ulrik, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Reichl, U., Bukh, Jens, Genzel, Y. & Gottwein, Judith Margarete, 2021, In: Vaccines. 9, 7, 706.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 12437