Thomas Werge
Clinical Professor
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GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
Chen, X., Lee, G., Maher, B. S., Fanous, A. H., Chen, J., Zhao, Z., Guo, A., van den Oord, E., Sullivan, P. F., Shi, J., Levinson, D. F., Gejman, P. V., Sanders, A., Duan, J., Owen, M. J., Craddock, N. J., O'Donovan, M. C., Blackman, J., Lewis, D., Kirov, G. K. & 42 others, , 2011, In: Molecular Psychiatry. 16, 11, p. 1117-29 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J. E., Murnyak, B., Wendt, F., Adams, M., Campos, A. I., DiBlasi, E., Fullerton, J. M., Kranzler, H. R., Bakian, A. V., Monson, E. T., Rentería, M. E., Walss-Bass, C., Andreassen, O. A., Behera, C. & 228 others, , 2023, In: American Journal of Psychiatry. 180, 10, p. 723-738 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C. B. D. W. G. O. T. P. G. C. S. W. G. O. T. P. G. C., Fanous, A. H., Kendler, K. S., McQuillin, A. & Lewis, C. M., 2019, In: American Journal of Psychiatry. 176, 8, p. 651-660Research output: Contribution to journal › Journal article › Research › peer-review
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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardiñas, A. F., Rajagopal, V. M., Als, T. D., T. Nguyen, H., Girdhar, K., Boocock, J., Roussos, P., Fromer, M., Kramer, R., Domenici, E., Gamazon, E. R., Purcell, S., CommonMind Consortium, The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium, iPSYCH-GEMS Schizophrenia Working Group & 15 others, , 2019, In: Nature Genetics. 51, p. 659-674Research output: Contribution to journal › Journal article › Research › peer-review
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Gene-Based Analysis of Regionally Enriched Cortical Genes in GWAS Data Sets of Cognitive Traits and Psychiatric Disorders
Ersland, K. M., Christoforou, A., Stansberg, C., Espeseth, T., Mattheisen, M., Mattingsdal, M., Hardarson, G. A., Hansen, T., Fernandes, C. P. D., Giddaluru, S., Breuer, R., Strohmaier, J., Djurovic, S., Nöthen, M. M., Rietschel, M., Lundervold, A. J., Werge, T., Cichon, S., Andreassen, O. A., Reinvang, I. & 2 others, , 2012, In: P L o S One. 7, 2, p. e31687Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations
Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A. & 31 others, , Dec 2017, In: JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Srinivasan, S., Bettella, F., Mattingsdal, M., Wang, Y., Witoelar, A., Schork, A. J., Thompson, W. K., Zuber, V., Winsvold, B. S., Zwart, J., Collier, D. A., Desikan, R. S., Melle, I., Werge, Thomas, Dale, A. M., Djurovic, S., Andreassen, O. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, S. W. G. O. T. P. G. C. T. I. H. G. C., 15 Aug 2016, In: Biological Psychiatry. 80, 4, p. 284-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume
Terwisscha van Scheltinga, A. F., Bakker, S. C., van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Boos, H. B. M., Cahn, W., Hulshoff Pol, H. E., Ripke, S., Ophoff, R. A., Kahn, R. S., the Psychiatric Genome-wide Association Study Consortium, Jakobsen, K. D., Hansen, T., Ingason, A., Duong, L., Rasmussen, H. B., Olsen, L., Nordentoft, M., Jürgens, G. & 3 others, , 2013, In: Advances in Biological Psychiatry. 73, 6, p. 525-531Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variants Associated with Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study
Meier, S. M., Trontti, K., Purves, K. L., Als, T. D., Grove, J., Laine, M., Pedersen, M. G., Bybjerg-Grauholm, J., Bækved-Hansen, M., Sokolowska, E., Mortensen, P. B., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Breen, G., Børglum, A. D., Eley, T. C., Hovatta, I., Mattheisen, M. & Mors, O., 2019, In: JAMA Psychiatry. 76, 9, p. 924-932 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic and epidemiological analyses of infection load and its relationship with psychiatric disorders
Nudel, R., Hougaard, D. M., Werge, Thomas & Benros, Michael Eriksen, 2023, In: Epidemiology and Infection. 151, 11 p., e93.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic and psychosocial influence on the association between early childhood infections and later psychiatric disorders
Debost, J. P. G., Thorsteinsson, E., Trabjerg, B., Benros, Michael Eriksen, Albiñana, C., Vilhjalmsson, B. J., Børglum, A., Mors, O., Werge, Thomas, Mortensen, P. B., Agerbo, E. & Vogdrup, L., 2022, In: Acta Psychiatrica Scandinavica. 146, 5, p. 406-419 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic assortative mating for schizophrenia and bipolar disorder
Jefsen, O. H., Nudel, R., Wang, Y., Bybjerg-Grauholm, J., Hemager, N., Christiani, C. A. J., Burton, B. K., Spang, K. S., Ellersgaard, D., Gantriis, D. L., Plessen, K. J., Jepsen, J. R. M., Thorup, Anne, Werge, Thomas, Nordentoft, Merete, Mors, O. & Greve, A. N., 2022, In: European Psychiatry. 65, 1, 7 p., e53.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic correlates of phenotypic heterogeneity in autism
Warrier, V., Zhang, X., Reed, P., Havdahl, A., Moore, T. M., Cliquet, F., Leblond, C. S., Rolland, T., Rosengren, A., Caceres, A. S. J., Hayward, H., Crawley, D., Faulkner, J., Sabet, J., Ellis, C., Oakley, B., Loth, E., Charman, T., Murphy, D., Holt, R. & 33 others, , 2022, In: Nature Genetics. 54, 9, p. 1293-1304 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots
Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B., Vilhjálmsson, B. J. & 1 others, , 2023, In: Nature Communications. 14, 16 p., 852.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A., Van Doormaal, P. T. C. & 31 others, , 2017, In: Nature Communications. 8, 14774.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic disposition towards educational attainment and intelligence test performance predict voter turnout
Aaroe, L., Appadurai, V., Hansen, Kasper Møller, Schork, A. J., Werge, Thomas, Mors, O., Borglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Thompson, W. K., Buil, A., Agerbo, E. & Petersen, M. B., 2021, In: Nature Human Behavior. 5, 2, p. 281-291 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study: [Incl. Corrigendum]
Liu, X., Nudel, R., Thompson, W. K., Appadurai, V., Schork, A. J., Buil, A., Rasmussen, Simon, Allesøe, R. L., Werge, Thomas, Mors, O., Børglum, A. D., Hougaard, D. M., Mortensen, P. B., Nordentoft, Merete & Benros, Michael Eriksen, 2021, In: Brain, Behavior, and Immunity. 91, p. 10-23 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
Bryois, J., Skene, N. G., Hansen, T. F., Kogelman, L. J. A., Watson, H. J., Liu, Z., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan, R., Alfredsson, L., Ando, T., Andreassen, O., Baker, J., Bergen, A., Berrettini, W., Birgegård, A., Boden, J., Boehm, I., Boni, C., Boraska Perica, V., Brandt, H. & 44 others, , May 2020, In: Nature Genetics. 52, p. 482-493Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic liability to ADHD and substance use disorders in individuals with ADHD
Wimberley, T., Agerbo, E., Horsdal, H. T., Ottosen, C., Brikell, I., Als, T. D., Demontis, D., Børglum, A. D., Nordentoft, Merete, Mors, O., Werge, Thomas, Hougaard, D., Bybjerg-Grauholm, J., Hansen, M. B., Mortensen, P. B., Thapar, A., Riglin, L., Langley, K. & Dalsgaard, S., 2020, In: Addiction. 115, 7, p. 1368-1377Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic liability to major depression and risk of childhood asthma
Liu, X., Munk-Olsen, T., Albiñana, C., Vilhjálmsson, B. J., Pedersen, E. M., Schlünssen, V., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Hougaard, D. M., Mortensen, P. B. & Agerbo, E., 2020, In: Brain, Behavior, and Immunity. 89, p. 433-439 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic liability to posttraumatic stress disorder and its association with postpartum depression
Bang Madsen, K., Liu, X., Albiñana, C., Jóhann Vilhjálmsson, B., Agerbo, E., Mortensen, P. B., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Mors, O., Børglum, A. D. & Munk-Olsen, T., 2023, In: Psychological Medicine. 53, 11, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study
Fadista, J., Yakimov, V., Võsa, U., Hansen, C. S., Kasela, S., Skotte, L., Geller, F., Courraud, J., Esko, T., Kukuškina, V., Buil, A., Melbye, M., Werge, Thomas, Hougaard, D. M., Milani, L., Bybjerg-Grauholm, J., Cohen, A. S. & Feenstra, B., 2021, In: Scientific Reports. 11, 17463.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B., Grove, J., Maller, J., Samocha, K. E., Sanders, J-S. F., Ripke, S., Martin, J., Hollegaard, M. V., Werge, T., Hougaard, D. M., Neale, B. M., Evans, D. M., Skuse, D., Mortensen, P. B., Børglum, A. D., Ronald, A. & 3 others, , 2016, In: Nature Genetics. 48, 5, p. 552-5 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis
Velthorst, E., Froudist-Walsh, S., Stahl, E., Ruderfer, D., Ivanov, I., Buxbaum, J., iPSYCH-Broad ASD Group, the IMAGEN consortium, Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Burke Quinlan, E., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Paillère Martinot, M. L. & 31 others, , 2018, In: Translational Psychiatry. 8, 1, 204.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
Lu, Y., Pouget, J. G., Andreassen, O. A., Djurovic, S., Esko, T., Hultman, C. M., Metspalu, A., Milani, L., Werge, Thomas & Sullivan, P. F., 2018, In: Psychological Medicine. 48, 7, p. 1201-1208 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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