Niels Erik Skakkebæk

Niels Erik Skakkebæk

Affiliate Professor

Member of:

  • Paediatrics


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  1. Published

    Secular decline in male testosterone and sex hormone binding globulin serum levels in Danish population surveys

    Andersson, A., Jensen, T. K., Juul, Anders, Petersen, Jørgen Holm, Jørgensen, T. & Skakkebæk, Niels Erik, 1 Dec 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4696-705 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Selection Biases in Semen Study?

    Skakkebæk, Niels Erik, Giwercman, A., Jensen, T. K., Carlsen, E., Jørgensen, N. & Keiding, N., Jun 1998, In: Fertility & Sterility. 69, 6, p. 1158-1159 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  3. Published

    Self-rated health and semen quality among 3,457 young Danish men

    Jensen, T. K., Jørgensen, N., Asklund, C., Carlsen, E., Kristensen, T. S., Holm, M., Skakkebæk, Niels Erik & Jensen, T. K., 1 Nov 2007, In: Fertility and Sterility. 88, 5, p. 1366-73 8 p.

    Research output: Contribution to journal › Journal article › Research

  4. Published

    Self-reported onset of puberty and subsequent semen quality and reproductive hormones in healthy young men

    Jensen, T. K., Finne, K. F., Skakkebæk, Niels Erik, Andersson, A., Olesen, I. A., Joensen, U. N., Bang, A. K., Nordkap, L., Priskorn, L., Krause, M., Jørgensen, N. & Juul, Anders, 2016, In: Human Reproduction. 31, 8, p. 1886-1894 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Semen quality and reproductive hormone levels in men from Southern Spain

    Fernandez, M. F., Duran, I., Olea, N., Avivar, C., Vierula, M., Toppari, J., Skakkebæk, Niels Erik & Jørgensen, N., 2012, In: International Journal of Andrology. 35, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Semen quality improves marginally during young adulthood: a longitudinal follow-up study

    Perheentupa, A., Sadov, S., Rönkä, R., Virtanen, H. E., Rodprasert, W., Vierula, M., Jørgensen, N., Skakkebæk, Niels Erik & Toppari, J., 2016, In: Human Reproduction. 31, 3, p. 502-10 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Semen quality in sub-fertile range for a significant proportion of young men from the general German population: a co-ordinated, controlled study of 791 men from Hamburg and Leipzig

    Paasch, U., Salzbrunn, A., Glander, H. J., Plambeck, K., Salzbrunn, H., Grunewald, S., Stucke, J., Vierula, M., Jorgensen, N. & Skakkebæk, Niels Erik, 2008, In: International Journal of Andrology. 31, 2, p. 93-102 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Semen quality of young men in Switzerland: a nationwide cross-sectional population-based study

    Rahban, R., Priskorn, L., Senn, A., Stettler, E., Galli, F., Vargas, J., Van den Bergh, M., Fusconi, A., Garlantezec, R., Jensen, T. K., Multigner, L., Skakkebæk, Niels Erik, Germond, M., Jørgensen, N., Nef, S. & The NICER Working Group, T. N. W. G., 2019, In: Andrology. 7, 6, p. 818-826

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Semen quality, reproductive hormones and fertility of men operated for hypospadias

    Asklund, C., Jensen, T. K., Main, Katharina Maria, Sobotka, T., Skakkebæk, Niels Erik & Jørgensen, N., 1 Feb 2010, In: International Journal of Andrology. 33, 1, p. 80-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Serum concentrations of Anti-Müllerian Hormone (AMH) in 95 patients with Klinefelter syndrome with or without cryptorchidism

    Aksglaede, L., Christiansen, P., Sørensen, K., Boas, M., Linneberg, Allan René, Main, Katharina Maria, Andersson, A., Skakkebæk, Niels Erik & Juul, Anders, 2011, In: Acta Paediatrica. 100, 6, p. 839-845 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Serum concentrations of free and total insulin-like growth factor-I, IGF binding proteins -1 and -3 and IGFBP-3 protease activity in boys with normal or precocious puberty

    Juul, Anders, Flyvbjerg, A., Frystyk, J., Müller, J. & Skakkebæk, Niels Erik, 1996, In: Clinical Endocrinology. 44, 5, p. 515-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Serum concentrations of type I and III procollagen propeptides in healthy children and girls with central precocious puberty during treatment with gonadotropin-releasing hormone analog and cyproterone acetate

    Hertel, N., Stoltenberg, M., Juul, Anders, Main, Katharina Maria, Müller, J., Nielsen, C. T., Lorenzen, I. & Skakkebæk, Niels Erik, 1993, In: Journal of Clinical Endocrinology and Metabolism. 76, 4, p. 924-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Serum inhibin A and inhibin B in healthy prepubertal, pubertal, and adolescent girls and adult women: relation to age, stage of puberty, menstrual cycle, follicle-stimulating hormone, luteinizing hormone, and estradiol levels

    Sehested, A., Juul, Anders, Andersson, A. M., Petersen, Jørgen Holm, Jensen, T. K., Müller, J. & Skakkebæk, Niels Erik, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 4, p. 1634-40 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Serum inhibin B in healthy pubertal and adolescent boys: relation to age, stage of puberty, and follicle-stimulating hormone, luteinizing hormone, testosterone, and estradiol levels

    Andersson, A. M., Juul, Anders, Petersen, J. H., Müller, J., Groome, N. P. & Skakkebæk, Niels Erik, 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 12, p. 3976-81 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Serum inhibin B, FSH, LH and testosterone levels before and after human chorionic gonadotropin stimulation in prepubertal boys with cryptorchidism

    Christiansen, P., Andersson, A., Skakkebæk, Niels Erik & Juul, Anders, 2002, In: European Journal of Endocrinology. 147, 1, p. 95-101 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Serum inhibin-b in fertile men is strongly correlated with low but not high sperm counts: a coordinated study of 1,797 European and US men

    Jørgensen, N., Liu, F., Andersson, A., Vierula, M., Irvine, D. S., Auger, J., Brazil, C. K., Drobnis, E. Z., Jensen, T. K., Jouannet, P., Overstreet, J. W., Redmon, J. B., Sparks, A., Toppari, J., Wang, C., Skakkebæk, Niels Erik & Swan, S. H., 1 Nov 2010, In: Fertility and Sterility. 94, 6, p. 2128-34 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 levels are increased in central precocious puberty: effects of two different treatment regimens with gonadotropin-releasing hormone agonists, without or in combination with an antiandrogen (cyproterone acetate)

    Juul, Anders, Scheike, T. H., Nielsen, C. T., Krabbe, S., Müller, J. & Skakkebæk, Niels Erik, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 10, p. 3059-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Serum insulin-like growth factor-I in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index

    Juul, Anders, Bang, P., Hertel, N., Main, Katharina Maria, Dalgaard, P., Jørgensen, K., Müller, J., Hall, K. P. & Skakkebæk, Niels Erik, 1994, In: Journal of Clinical Endocrinology and Metabolism. 78, 3, p. 744-52 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnancies

    Ekbom, P., Damm, Peter, Andersson, A., Skakkebæk, Niels Erik, Feldt-Rasmussen, Ulla & Mathiesen, Elisabeth, 1 Jan 2006, In: Acta Obstetricia et Gynecologica Scandinavica. 85, 2, p. 143-7 5 p.

    Research output: Contribution to journal › Journal article › Research

  20. Published

    Serum levels of growth hormone binding protein in children with normal and precocious puberty: relation to age, gender, body composition and gonadal steroids

    Juul, Anders, Fisker, S., Scheike, T. H., Hertel, T. K., Müller, J., Orskov, H. & Skakkebæk, Niels Erik, 2000, In: Clinical Endocrinology. 52, 2, p. 165-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Serum levels of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: the relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index, and pubertal maturation

    Juul, Anders, Dalgaard, P., Blum, W. F., Bang, P., Hall, K. P., Michaelsen, K. F., Müller, J. & Skakkebæk, Niels Erik, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 8, p. 2534-42 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Serum levels of insulin-like growth factor-1 in first trimester of diabetic pregnancy: relation to early growth delay

    Pedersen, J. F., Juul, Anders, Mølsted-Pedersen, L. & Skakkebæk, Niels Erik, 1995, In: B J O G. 102, 11, p. 927-8 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Serum sex hormone-binding globulin levels in healthy children and girls with precocious puberty before and during gonadotropin-releasing hormone agonist treatment

    Sørensen, K., Andersson, A. M., Skakkebæk, Niels Erik & Juul, Anders, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 3189-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Serum testosterone levels in three-month-old boys predict their semen quality as young adults

    Scheutz Henriksen, L., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Jørgensen, N., Virtanen, H. E., Priskorn, Lærke, Juul, Anders, Toppari, J. & Main, Katharina Maria, 2022, In: The Journal of clinical endocrinology and metabolism. 107, 7, p. 1965–1975 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Sex chromosome aneuploidy and anthropometry

    Aksglæde, L., Skakkebæk, Niels Erik & Juul, Anders, 2011, Handbook of Anthropometry: Physical measures of human form in health and disease. Springer

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  26. Published

    Sex differences in the vaccine-specific and non-targeted effects of vaccines

    Flanagan, K. L., Klein, S. L., Skakkebæk, Niels Erik, Marriott, I., Marchant, A., Selin, L., Fish, E. N., Prentice, A. M., Whittle, H., Benn, C. S. & Aaby, P., 16 Mar 2011, In: Vaccine. 29, 13, p. 2349-54 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Short-term effect of recombinant human growth hormone in patients with alcoholic cirrhosis

    Møller, S., Becker, U., Grønbaek, M., Juul, Anders, Winkler, K. & Skakkebæk, Niels Erik, 1994, In: Journal of Hepatology. 21, 5, p. 710-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Skin morphological changes in growth hormone deficiency and acromegaly

    Lange, M. W., Thulesen, J., Feldt-Rasmussen, Ulla, Skakkebæk, Niels Erik, Vahl, N., Jørgensen, J. O., Christiansen, J. S., Poulsen, Steen Seier, Sneppen, S. B. & Juul, Anders, 2001, In: European Journal of Endocrinology. 145, 2, p. 147-153 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Smaller genitals at school age in boys whose mothers were exposed to non-persistent pesticides in early pregnancy

    Veje, C. W., Andersen, H. R., Jensen, T. K., Grandjean, P., Skakkebæk, Niels Erik & Main, Katharina Maria, 2012, In: International Journal of Andrology. 35, 3, p. 265-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number

    Mau Kai, C., Juul, Anders, McElreavey, K., Ottesen, A. M., Garn, I. D., Main, Katharina Maria, Loft, A., Jørgensen, N., Skakkebæk, Niels Erik, Andersen, A. N. & Rajpert-De Meyts, E., 2008, In: Human Reproduction. 23, 7, p. 1669-1678 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Special issue on the impact of endocrine disrupters on reproductive health

    Andersson, A., Bay, K., Grigor, K. M., Meyts, E. R. & Skakkebæk, Niels Erik, 2012, In: International Journal of Andrology. 35, 3, p. 215

    Research output: Contribution to journal › Journal article › Research

  32. Published

    Sperm Concentration, Testicular Volume and Age Predict Risk of Carcinoma In Situ in Contralateral Testis of Men with Testicular Germ Cell Cancer

    Rud, C. N., Daugaard, G., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Petersen, Jørgen Holm & Jørgensen, N., 2013, In: Journal of Urology. 190, 6, p. 2074-2080 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Sperm counts, testicular cancers, and the environment

    Skakkebæk, Niels Erik, 10 Oct 2017, In: B M J. 359, j4517.

    Research output: Contribution to journal › Editorial › Research

  34. Published

    Sperm decline: Real or artifact?

    Keiding, N. & Skakkebæk, Niels Erik, 1 Jan 1996, In: Fertility and Sterility. 65, 2, p. 450-451 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  35. Published

    Sperm retrieval in adolescent males with Klinefelter syndrome: medical and ethical issues

    Rogol, A. D. & Skakkebæk, Niels Erik, Apr 2016, In: Translational Pediatrics. 5, 2, p. 104-106

    Research output: Contribution to journal › Comment/debate › Research

  36. Published

    Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology

    Björndahl, L., Barratt, C. L. R., Mortimer, D., Agarwal, A., Aitken, R. J., Alvarez, J. G., Aneck-Hahn, N., Arver, S., Baldi, E., Bassas, L., Boitrelle, F., Bornman, R., Carrell, D. T., Castilla, J. A., Cerezo Parra, G., Check, J. H., Cuasnicu, P. S., Darney, S. P., de Jager, C., De Jonge, C. J. & 67 others, Drevet, J. R., Drobnis, E. Z., Du Plessis, S. S., Eisenberg, M. L., Esteves, S. C., Evgeni, E. A., Ferlin, A., Garrido, N., Giwercman, A., Goovaerts, I. G. F., Haugen, T. B., Henkel, R., Henningsohn, L., Hofmann, M. C., Hotaling, J. M., Jedrzejczak, P., Jouannet, P., Jørgensen, N., Kirkman Brown, J. C., Krausz, C., Kurpisz, M., Kvist, U., Lamb, D. J., Levine, H., Loveland, K. L., McLachlan, R. I., Mahran, A., Maree, L., Martins da Silva, S., Mbizvo, M. T., Meinhardt, A., Menkveld, R., Mortimer, S. T., Moskovtsev, S., Muller, C. H., Munuce, M. J., Muratori, M., Niederberger, C., O'Flaherty, C., Oliva, R., Ombelet, W., Pacey, A. A., Palladino, M. A., Ramasamy, R., Ramos, L., Rives, N., Roldan, E. R., Rothmann, S., Sakkas, D., Salonia, A., Sánchez-Pozo, M. C., Sapiro, R., Schlatt, S., Schlegel, P. N., Schuppe, H. C., Shah, R., Skakkebæk, Niels Erik, Teerds, K., Toskin, I., Tournaye, H., Turek, P. J., van der Horst, G., Vazquez-Levin, M., Wang, C., Wetzels, A., Zeginiadou, T. & Zini, A., 2022, In: Human Reproduction. 37, 11, p. 2497-2502 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours

    Hoei-Hansen, C. E., Almstrup, Kristian, Nielsen, J. E., Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2005, In: Histopathology. 47, 1, p. 48-56 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Sunscreens: are they beneficial for health? An overview of endocrine disrupting properties of UV-filters

    Krause, M., Klit, A., Jensen, M. B., Søeborg, T., Frederiksen, H., Schlumpf, M., Lichtensteiger, W., Skakkebæk, Niels Erik & Drzewiecki, K. T., 2012, In: International Journal of Andrology. 35, 3, p. 424-36 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Sweat secretion rates in growth hormone disorders

    Sneppen, S. B., Main, Katharina Maria, Juul, Anders, Pedersen, L. M., Kristensen, L. O., Skakkebæk, Niels Erik & Feldt-Rasmussen, Ulla, 2000, In: Clinical Endocrinology. 53, 5, p. 601-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Synergistic activation of CatSper Ca2+ channels in human sperm by oviductal ligands and endocrine disrupting chemicals

    Brenker, C., Rehfeld, Anders Aagaard, Schiffer, C., Kierzek, M., Kaupp, U. B., Skakkebæk, Niels Erik & Strünker, T., 2018, In: Human Reproduction. 33, 10, p. 1915-1923 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Temporal Trends in Fertility Rates: A Nationwide Registry Based Study from 1901 to 2014

    Jensen, M. B., Priskorn, L., Jensen, T. K., Juul, Anders & Skakkebæk, Niels Erik, 2015, In: P L o S One. 10, 12, p. 1-10 10 p., e0143722.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Temporal variability in urinary excretion of bisphenol A and seven other phenols in spot, morning, and 24-h urine samples

    Lassen, T. H., Frederiksen, H., Jensen, T. K., Petersen, Jørgen Holm, Main, Katharina Maria, Skakkebæk, Niels Erik, Jørgensen, N., Kranich, S. K. & Andersson, A. M., 2013, In: Environmental Research. 126, p. 164-170 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Testicular Dysgenesis Syndrom and Carcinoma In Situ Testis

    Rajpert-De Meyts, E., Almstrup, H. K. & Skakkebæk, Niels Erik, 2012, Atlas on the Human Testis. Jezek, D. (ed.). p. 159-178 19 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  44. Published

    Testicular Dysgenesis Syndrome and Carcinoma In Situ Testis

    Meyts, E. R., Almstrup, Kristian & Skakkebæk, Niels Erik, 17 Sep 2012, Atlas on the Human Testis.. Springer London, p. 159-178

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  45. Published

    Testicular Growth During Puberty in Boys With and Without a History of Congenital Cryptorchidism

    Sadov, S., Koskenniemi, J. J., Virtanen, H. E., Perheentupa, A., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Main, Katharina Maria & Toppari, J., Jun 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 6, p. 2570–2577 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Testicular cancer: New inroads into early diagnosis

    Rajpert-De Meyts, E., Znaor, A. & Skakkebæk, Niels Erik, 2020, World Cancer Report: Cancer Research for Cancer Prevention. Wild, C. P., Weiderpass, E. & Stewart, B. W. (eds.). IARC Press, p. 430-438 (World Cancer Reports).

    Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research › peer-review

  47. Published

    Testicular cancer incidence predictions in Europe 2010–2035: A rising burden despite population ageing

    Znaor, A., Skakkebæk, Niels Erik, Rajpert‐de Meyts, E., Laversanne, M., Kuliš, T., Gurney, J., Sarfati, D., Mcglynn, K. A. & Bray, F., 2020, In: International Journal of Cancer. 147, 3, p. 820-828

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations

    Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Jørgensen, N., Main, Katharina Maria, Leffers, H., Andersson, A., Juul, Anders, Jensen, T. K. & Toppari, J., 2007, In: International Journal of Andrology. 30, 4, p. 198-204; discussion 204-5

    Research output: Contribution to journal › Review › Research

  49. Published

    Testicular descent: INSL3, testosterone, genes and the intrauterine milieu

    Bay, K., Main, Katharina Maria, Toppari, J., Skakkebæk, Niels Erik & Medscape, M., 15 Mar 2011, In: Nature Reviews. Urology.

    Research output: Contribution to journal › Journal article › Research

  50. Published

    Testicular dysgenesis syndrome and carcinoma in situ of the testes

    Joensen, Ulla Nordström, Jorgensen, N. & Skakkebæk, Niels Erik, Aug 2007, In: Nature Clinical Practice Urology. 4, 8, p. 402-403 2 p.

    Research output: Contribution to journal › Review › Research › peer-review

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