Niels Erik Skakkebæk

Niels Erik Skakkebæk

Affiliate Professor

Member of:

  • Paediatrics


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  1. Published

    Possible developmental early effects of endocrine disrupters on child health

    Toppari, J., Adamsson, A., Boas, M., Juul, Anders, Main, Katharina Maria, Skakkebæk, Niels Erik & Virtanen, H., 2012, WHO report 2012. p. 1-83

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  2. Published

    Possible fetal determinants of male infertility

    Juul, Anders, Almstrup, Kristian, Andersson, A., Jensen, T. K., Jørgensen, N., Main, K. M., Rajpert-De Meyts, E., Toppari, J. & Skakkebæk, Niels Erik, Sep 2014, In: Nature Reviews Endocrinology. 10, 9, p. 553-562 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Possible involvement of the glucocorticoid receptor (NR3C1) and selected NR3C1 gene variants in regulation of human testicular function

    Nordkap, L., Almstrup, Kristian, Nielsen, J. E., Bang, A. K., Priskorn, L., Krause, M., Holmboe, S. A., Winge, S. B., Egeberg Palme, D. L., Mørup, N., Petersen, Jørgen Holm, Juul, A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Jørgensen, N., Nov 2017, In: Andrology. 5, 6, p. 1105-1114 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Postnatal Changes in Testicular Position Are Associated With IGF-I and Function of Sertoli and Leydig Cells

    Koskenniemi, J. J., Virtanen, H. E., Wohlfahrt-Veje, C., Löyttyniemi, E., Skakkebæk, Niels Erik, Juul, Anders, Andersson, A., Main, Katharina Maria & Toppari, J., 2018, In: The Journal of clinical endocrinology and metabolism. 103, 4, p. 1429-1437

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring: A Nationwide Cohort Study

    Wensink, M. J., Lu, Y., Tian, L., Shaw, G. M., Rizzi, S., Jensen, T. K., Mathiesen, Elisabeth, Skakkebæk, Niels Erik, Lindahl-Jacobsen, R. & Eisenberg, M. L., 2022, In: Annals of Internal Medicine. 175, 5, p. 665-673 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Predicting and monitoring of growth in children with short stature during the first year of growth hormone treatment

    Mortensen, H. B., Main, Katharina Maria, Michaelsen, Kim F., Kastrup, K. W., Jørgensen, J. T. & Skakkebæk, Niels Erik, 1991, In: Acta Paediatrica Scandinavica. 80, 12, p. 1150-1157 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Prediction of the outcome of growth hormone provocative testing in short children by measurement of serum levels of insulin-like growth factor I and insulin-like growth factor binding protein 3

    Juul, Anders & Skakkebæk, Niels Erik, 1997, In: Journal of Pediatrics. 130, 2, p. 197-204 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Prenatal Exposure to Phthalates and Anogenital Distance in Male Infants from a Low-Exposed Danish Cohort (2010-2012)

    Jensen, T. K., Frederiksen, H., Kyhl, H. B., Lassen, T. H., Swan, S. H., Bornehag, C., Skakkebæk, Niels Erik, Main, Katharina Maria, Lind, D. V., Husby, S. & Andersson, A., Jul 2016, In: Environmental Health Perspectives. 124, 7, p. 1107-13 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Prenatal Triclosan Exposure and Anthropometric Measures Including Anogenital Distance in Danish Infants

    Lassen, T. H., Frederiksen, H., Kyhl, H. B., Swan, S. H., Main, Katharina Maria, Andersson, A. M., Lind, D. V., Husby, S., Wohlfahrt-Veje, C., Skakkebæk, Niels Erik & Jensen, T. K., Aug 2016, In: Environmental Health Perspectives. 124, 8, p. 1261-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Prenatal and adult exposures to smoking are associated with adverse effects on reproductive hormones, semen quality, final height and body mass index

    Ravnborg, T. L., Jensen, T. K., Andersson, A., Toppari, J., Skakkebæk, Niels Erik & Jørgensen, N., 18 Feb 2011, In: Human Reproduction. 26, 5, p. 1000-1011 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study

    Mogensen, D. M., Pihl, M. B., Skakkebæk, Niels Erik, Andersen, H. R., Juul, Anders, Kyhl, H. B., Swan, S., Kristensen, D. M., Andersen, M. S., Lind, D. V. & Jensen, T. K., 2017, In: Environmental Health. 16, 8 p., 68.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Prenatal exposure to phenols and benzophenones in relation to markers of male reproductive function in adulthood

    Holmboe, S. A., Scheutz Henriksen, L., Frederiksen, H., Andersson, A. M., Priskorn, Lærke, Jørgensen, N., Juul, Anders, Toppari, J., Skakkebæk, Niels Erik & Main, Katharina Maria, 2022, In: Frontiers in Endocrinology. 13, 1071761.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Prenatal pesticide exposure and PON1 genotype associated with adolescent body fat distribution evaluated by dual X-ray absorptiometry (DXA)

    Tinggaard, J., Wohlfahrt-Veje, C., Husby, S., Christiansen, L., Skakkebæk, Niels Erik, Jensen, T. K., Grandjean, P., Main, Katharina Maria & Andersen, H. R., Jul 2016, In: Andrology. 4, 4, p. 735-744 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Presence of benzophenones commonly used as UV filters and absorbers in paired maternal and fetal samples

    Krause, M., Frederiksen, H., Sundberg, K., Jørgensen, F. S., Jensen, L. N., Nørgaard, P., Jørgensen, C., Ertberg, P., Juul, Anders, Drzewiecki, K. T., Skakkebæk, Niels Erik & Andersson, A. M., 2018, In: Environment International. 110, p. 51-60 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Preserved fertility in a non-mosaic Klinefelter patient with a mutation in the fibroblast growth factor receptor 3 gene: case report

    Juul, Anders, Aksglaede, L., Lund, Allan Meldgaard, Duno, M., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 2007, In: Human Reproduction. 22, 7, p. 1907-11 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries

    Teilmann, Grete Katrine, Pedersen, C., Jensen, T. K., Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Pediatrics. 116, 6, p. 1323-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Primary testicular failure in Klinefelter's syndrome: the use of bivariate luteinizing hormone-testosterone reference charts

    Aksglaede, L., Andersson, A., Jørgensen, N., Jensen, T. K., Carlsen, E., McLachlan, R. I., Skakkebæk, Niels Erik, Petersen, Jørgen Holm & Juul, Anders, 1 Feb 2007, In: Clinical Endocrinology. 66, 2, p. 276-81 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Proceedings of the 5th Copenhagen Workshop on endocrine disrupters: ubiquitous endocrine disrupters and possible human health effects. Preface

    Andersson, A., Bay, K., Grigor, K. M., Toppari, J. & Skakkebæk, Niels Erik, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 251 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Proceedings of the 7th Copenhagen Workshop on Testicular Carcinoma in situ and Germ Cell Cancer, 13-15 October 2010

    Rajpert-De Meyts, E., Grigor, K. M. & Skakkebæk, Niels Erik, 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e1

    Research output: Contribution to journal › Journal article › Research

  20. Published

    Proceedings: 17beta-hydroxysteroid oxidoreductase deficiency causing male pseudohermaphroditism in a child

    Harkness, R. A., Thistlethwaite, D., Darling, J. A., Skakkebæk, Niels Erik & Corker, C. S., 1 Nov 1975, In: Journal of Endocrinology. 67, 2, p. 16P-17P

    Research output: Contribution to journal › Journal article › Research

  21. Prognostic value of insulinlike growth factor I and its binding protein in patients with alcohol-induced liver disease

    The EMALD Group, T. E. G., May 1996, In: Hepatology. 23, 5, p. 1073-1078 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Proliferation of Sertoli cells during development of the human testis assessed by stereological methods

    Cortes, Dina, Müller, J. & Skakkebæk, Niels Erik, 1 Aug 1987, In: International Journal of Andrology. 10, 4, p. 589-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Prolonged expression of the c-kit receptor in germ cells of intersex fetal testes

    Rajpert-De Meyts, E., Jørgensen, N., Müller, J. & Skakkebæk, Niels Erik, 1 Feb 1996, In: Journal of Pathology. 178, 2, p. 166-9 4 p.

    Research output: Contribution to journal › Journal article › Research

  24. Published

    Proposed Key Characteristics of Male Reproductive Toxicants as an Approach for Organizing and Evaluating Mechanistic Evidence in Human Health Hazard Assessments

    Arzuaga, X., Smith, M. T., Gibbons, C. F., Skakkebæk, Niels Erik, Yost, E. E., Beverly, B. E. J., Hotchkiss, A. K., Hauser, R., Pagani, R. L., Schrader, S. M., Zeise, L. & Prins, G. S., 2019, In: Environmental Health Perspectives. 127, 6, p. 1-12 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment

    Juul, Anders, Müller, J. & Skakkebæk, Niels Erik, 1997, In: European Journal of Endocrinology. 136, 4, p. 401-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Psychological stress and testicular function: a cross-sectional study of 1,215 Danish men

    Nordkap, L., Jensen, T. K., Hansen, Åse Marie, Lassen, T. H., Bang, A. K., Joensen, Ulla Nordström, Jensen, Martin Blomberg, Skakkebæk, Niels Erik & Jørgensen, N., Jan 2016, In: Fertility and Sterility. 105, 1, p. 174-187.e2 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Pubarche and Gonadarche Onset and Progression Are Differently Associated with Birth Weight and Infancy Growth Patterns

    Wohlfahrt-Veje, C., Tinggaard, J., Juul, Anders, Toppari, J., Skakkebæk, Niels Erik & Main, Katharina Maria, 1 Aug 2021, In: Journal of the Endocrine Society. 5, 8, 14 p., bvab108.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Pubertal Onset in Boys and Girls Is Influenced by Pubertal Timing of Both Parents

    Wohlfahrt-Veje, C., Mouritsen, A., Hagen, C. P., Tinggaard, J., Mieritz, M. G., Boas, M., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Main, Katharina Maria, Jul 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 7, p. 2667–2674 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Pubertal development in Danish children: comparison of recent European and US data

    Juul, Anders, Teilmann, Grete Katrine, Scheike, T. H., Hertel, N., Holm, Kirsten, Laursen, E., Main, Katharina Maria & Skakkebæk, Niels Erik, 2006, In: International Journal of Andrology. 29, 1, p. 247-55; discussion 286-90

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Putative effects of endocrine disrupters on pubertal development in the human

    Teilmann, Grete Katrine, Juul, Anders, Skakkebæk, Niels Erik & Toppari, J., 2002, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 16, 1, p. 105-21 17 p.

    Research output: Contribution to journal › Journal article › Research

  31. Published

    Quantification of the Leydig cell compartment in testicular biopsies and association with biochemical Leydig cell dysfunction in testicular cancer survivors

    Tarsitano, M. G., Bandak, M., Jørgensen, N., Skakkebæk, Niels Erik, Juul, Anders, Lenzi, A., Daugaard, G. & Rajpert-De Meyts, E., 2018, In: Andrology. 6, 5, p. 748-755 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Re: Niels J. van Casteren, Hans Stoop, Gert R. Dohle, Ronald de Wit, J. Wolter Oosterhuis, Leendert H.J. Looijenga. Noninvasive Detection of Testicular Carcinoma In Situ in Semen Using OCT3/4. Eur Urol 2008;54:153-60

    Høi-Hansen, Christina Engel, Almstrup, Kristian, Skakkebæk, Niels Erik & Rajpert-De Meyts, E., Apr 2009, In: European Urology. 55, 4, p. e67-e68

    Research output: Contribution to journal › Letter › Research › peer-review

  33. Published

    Re: The true incidence of cryptorchidism in Denmark: D. Cortes, E. M. Kjellberg, M. Breddam and J. Thorup, J Urol 2008; 179: 314-318

    Thorup, Jørgen Mogens, Cortes, Dina, Main, Katharina Maria, Skakkebæk, Niels Erik & Toppari, J., Feb 2009, In: The Journal of Urology. 181, 2, p. 922-4 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Re: The relationship of sperm counts to birth rates: A population based study

    Keiding, N. & Skakkebæk, Niels Erik, Jun 1998, In: Journal of Urology. 159, 6, p. 2103-2103 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  35. Published

    Recent adverse trends in semen quality and testis cancer incidence among Finnish men

    Jørgensen, N., Vierula, M., Jacobsen, R., Pukkala, E., Perheentupa, A., Virtanen, H. E., Skakkebæk, Niels Erik & Toppari, J., 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e37-48

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Recent decline in age at breast development: the Copenhagen Puberty Study

    Aksglaede, L., Sørensen, K., Petersen, J. H., Skakkebæk, Niels Erik & Juul, Anders, 2009, In: Pediatrics. 123, 5, p. e932-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Recent decline in age at breast development: the Copenhagen Puberty Study

    Aksglaede, L., Sørensen, K., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Juul, Anders, 2009, In: Pediatrics Electronic Pages. 123, 5, p. e932-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Reduced serum testosterone levels in infant boys conceived by intracytoplasmic sperm injection

    Mau Kai, C., Main, Katharina Maria, Andersen, A. N., Loft, A., Skakkebæk, Niels Erik & Juul, Anders, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 7, p. 2598-603 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Regional differences in waiting time to pregnancy among fertile couples from four European cities

    Kold-Jensen, T., Slama, R., Ducot, B., Suominen, J., Cawood, E. H. H., Andersen, A. G., Eustache, F., Irvine, S., Auger, S., Jouannet, P., Vierula, M., Jørgensen, N., Toppari, J., Skakkebæk, Niels Erik, Keiding, N. & Spira, A., 1 Dec 2001, In: Human Reproduction. 16, 12, p. 2697-2704 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Reply to Eugenio Ventimiglia, Francesco Montorsi, and Andrea Salonia's Letter to the Editor re: Jakob Damsgaard, Ulla N. Joensen, Elisabeth Carlsen, et al. Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries. Eur Urol 2016;70:1019-29

    Damsgaard, J., Joensen, Ulla Nordström, Carlsen, E., Erenpreiss, J., Jensen, M. B., Matulevicius, V., Zilaitiene, B., Olesen, I. A., Perheentupa, A., Punab, M., Salzbrunn, A., Toppari, J., Virtanen, H. E., Juul, Anders, Skakkebæk, Niels Erik & Jørgensen, N., 2017, In: European Urology. 71, 2, p. e71-e72

    Research output: Contribution to journal › Comment/debate › Research

  41. Published

    Reply to ‘Paracetamol use in pregnancy — caution over causal inference from available data’; ‘Handle with care — interpretation, synthesis and dissemination of data on paracetamol in pregnancy’

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., M. Andrade, A., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 3, p. 192 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  42. Published

    Reply to ‘Paracetamol use in pregnancy — neglecting context promotes misinterpretation’

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 1 p., 386.

    Research output: Contribution to journal › Letter › Research › peer-review

  43. Published

    Reproductive Markers of Testicular Function and Size During Puberty in Boys With and Without a History of Cryptorchidism

    Rodprasert, W., Koskenniemi, J. J., Virtanen, H. E., Sadov, S., Perheentupa, A., Ollila, H., Albrethsen, J., Andersson, A., Juul, Anders, Skakkebæk, Niels Erik, Main, Katharina Maria & Toppari, J., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 12, p. 3353-3361 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Reproductive hormone levels in Minipuberty as a predictor of Testicular Endocrine Function and Penile Length in Healthy Young Men: An 18-year longitudinal Cohort Study

    Henriksen, L. S., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Jørgensen, N., Virtanen, H. E., Juul, Anders, Toppari, J. & Main, Katharina Maria, 2021, In: Hormone Research in Paediatrics. 94, SUPPL 1, p. 41-42 2 p., FC5.4.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  45. Published

    Rise in semen quality between 1970 and 1990 in meta-analysis was non-significant

    Keiding, N. & Skakkebæk, Niels Erik, 6 Jul 1996, In: BMJ. 313, 7048, p. 44-44 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  46. Published

    Role of environmental factors in the timing of puberty

    Euling, S. Y., Selevan, S. G., Pescovitz, O. H. & Skakkebæk, Niels Erik, 2008, In: Pediatrics. 121 Suppl 3, p. S167-S171

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Science and policy on endocrine disrupters must not be mixed: a reply to a “common sense” intervention by toxicology journal editors

    Bergman, Å., Andersson, A-M., Becher, G., van den Berg, M., Blumberg, B., Bjerregaard, P., Bornehag, C-G., Bornman, R., Brandt, I., Brian, J. V., Casey, S. C., Fowler, P. A., Frouin, H., Giudice, L. C., Iguchi, T., Hass, U., Jobling, S., Juul, A., Kidd, K. A., Kortenkamp, A. & 21 others, Lind, M., Martin, O. V., Muir, D., Ochieng, R., Olea, N., Norrgren, L., Ropstad, E., Ross, P. S., Rudén, C., Scheringer, M., Skakkebæk, Niels Erik, Söder, O., Sonnenschein, C., Soto, A., Swan, S., Toppari, J., Tyler, C. R., Vandenberg, L. N., Vinggaard, A. M., Wiberg, K. & Zoeller, R. T., 2013, In: Environmental Health. 12, 69, p. 1-4 4 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  48. Published

    Screening for carcinoma in situ in the contralateral testicle in patients with testicular cancer: a population-based study

    Kier, M. G. G., Lauritsen, J., Almstrup, Kristian, Mortensen, M. S., Toft, Birgitte Grønkær, Meyts, E. R., Skakkebæk, Niels Erik, Rørth, M. R., von der Maase, H. R. R., Agerbæk, M., Holm, N. V., Andersen, K. K., Dalton, Susanne Oksbjerg, Johansen, Christoffer & Daugaard, G., Apr 2015, In: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 26, 4, p. 737-742 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Screening for carcinoma in situ of the contralateral testis in patients with germinal testicular cancer

    Berthelsen, Jens, Skakkebæk, Niels Erik, von der Maase, H., Sørensen, B. L. & Mogensen, P., 1982, In: British medical journal (Clinical research ed.). 285, 6356, p. 1683-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Screening of subfertile men for testicular carcinoma in situ by an automated image analysis-based cytological test of the ejaculate

    Almstrup, Kristian, Lippert, M., Mogensen, H. O., Nielsen, J. E., Hansen, J. D., Daugaard, G., Jørgensen, N., Foged, N., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e21-30; discussion e30-1

    Research output: Contribution to journal › Journal article › Research › peer-review

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