Cord Herbert Brakebusch

Cord Herbert Brakebusch


  1. Published

    Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis.

    Sitnicka, E., Brakebusch, Cord Herbert, Martensson, I., Svensson, M., Agace, W. W., Sigvardsson, M., Buza-Vidas, N., Bryder, D., Cilio, C. M., Ahlenius, H., Maraskovsky, E., Peschon, J. J. & Jacobsen, S. E. W., 2003, In: Journal of Experimental Medicine. 198, 10, p. 1495-506 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Conditional beta1-integrin gene deletion in neural crest cells causes severe developmental alterations of the peripheral nervous system.

    Pietri, T., Eder, O., Breau, M. A., Topilko, P., Blanche, M., Brakebusch, Cord Herbert, Fässler, R., Thiery, J. & Dufour, S., 2004, In: Development. 131, 16, p. 3871-83 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver.

    van Hengel, J., D'Hooge, P., Hooghe, B., Wu, X., Libbrecht, L., De Vos, R., Quondamatteo, F., Klempt, M., Brakebusch, Cord Herbert & van Roy, F., 2008, In: Gastroenterology. 134, 3, p. 781-92 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Control of Homeostasis and Dendritic Cell Survival by the GTPase RhoA

    Li, S., Dislich, B., Brakebusch, Cord Herbert, Lichtenthaler, S. F. & Brocker, T., 1 Nov 2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 9, p. 4244-56 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Control of cortical cytoskeleton-membrane interaction by RhoA regulates peripheral nerve myelination

    Seixas, A. I., Morais, M. R. G., Brakebusch, Cord Herbert & Relvas, J. B., 2022, Cold Spring Harbor Laboratory, 15 p. (bioRxiv).

    Research output: Working paperPreprint

  6. Published

    Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin

    Woodham, E. F., Paul, N. R., Tyrrell, B., Spence, H. J., Swaminathan, K., Scribner, M. R., Giampazolias, E., Hedley, A., Clark, W., Kage, F., Marston, D. J., Hahn, K. M., Tait, S. W. G., Larue, L., Brakebusch, Cord Herbert, Insall, R. H. & Machesky, L. M., 6 Mar 2017, In: Current biology : CB. 27, 5, p. 624-637 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets

    Dütting, S., Heidenreich, J., Cherpokova, D., Amin, E., Zhang, S., Ahmadian, M. R., Brakebusch, Cord Herbert & Nieswandt, B., May 2015, In: Journal of Thrombosis and Haemostasis. 13, 5, p. 827-38 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor.

    Brakebusch, Cord Herbert, Nophar, Y., Kemper, O., Engelmann, H. & Wallach, D., 1992, In: EMBO Journal. 11, 3, p. 943-50 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Cytoskeletal stability in the auditory organ in vivo: RhoA is dispensable for wound healing but essential for hair cell development

    Anttonen, T., Belevich, I., Laos, M., Herranen, A., Jokitalo, E., Brakebusch, Cord Herbert & Pirvola, U., 2017, In: eNeuro. 4, 5, 17 p., e0149-17.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

    Laviña, B., Castro, M., Niaudet, C., Cruys, B., Álvarez-Aznar, A., Carmeliet, P., Bentley, K., Brakebusch, Cord Herbert, Betsholtz, C. & Gaengel, K., 2 Jul 2018, In: Development (Cambridge, England). 145, 13, 20 p., dev161182.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

    Pleines, I., Dütting, S., Cherpokova, D., Eckly, A., Meyer, I., Morowski, M., Krohne, G., Schulze, H., Gachet, C., Debili, N., Brakebusch, Cord Herbert & Nieswandt, B., 31 Oct 2013, In: Blood. 122, 18, p. 3178-87 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Differential effect on TCR:CD3 stimulation of a 90-kD glycoprotein (gp90/Mac-2BP), a member of the scavenger receptor cysteine-rich domain protein family.

    Silvestri, B., Calderazzo, F., Coppola, V., Rosato, A., Iacobelli, S., Natoli, C., Ullrich, A., Sures, I., Azam, M., Brakebusch, Cord Herbert, Chieco-Bianchi, L. & Amadori, A., 1998, In: Clinical and Experimental Immunology. 113, 3, p. 394-400 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Discoidin domain receptor 1 is activated independently of beta(1) integrin.

    Vogel, W., Brakebusch, Cord Herbert, Fässler, R., Alves, F., Ruggiero, F. & Pawson, T., 2000, In: Journal of Biological Chemistry. 275, 8, p. 5779-84 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Distinct roles for dystroglycan, beta1 integrin and perlecan in cell surface laminin organization.

    Henry, M. D., Satz, J. S., Brakebusch, Cord Herbert, Costell, M., Gustafsson, E., Fässler, R. & Campbell, K. P., 2001, In: Journal of Cell Science. 114, Pt 6, p. 1137-44 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury

    Blattner, S. M., Hodgin, J. B., Nishio, M., Wylie, S. A., Saha, J., Soofi, A. A., Vining, C., Randolph, A., Herbach, N., Wanke, R., Atkins, K. B., Gyung Kang, H., Henger, A., Brakebusch, Cord Herbert, Holzman, L. B. & Kretzler, M., 15 May 2013, In: Kidney International.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity.

    Bigda, J., Beletsky, I., Brakebusch, Cord Herbert, Varfolomeev, Y., Engelmann, H., Bigda, J., Holtmann, H. & Wallach, D., 1994, In: Journal of Experimental Medicine. 180, 2, p. 445-60 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

    Martin Gonzalez, Javier, Morgani, S. M., Bone, Robert Alexander, Bonderup, K., Abelechian, Sahar, Brakebusch, Cord Herbert & Brickman, Joshua Mark, 9 Aug 2016, In: Stem Cell Reports. 7, 2, p. 177-91 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation

    Li, H., Yao, Q., Mariscal, A. G., Wu, X., Hülse, J., Pedersen, E., Helin, K., Waisman, A., Vinkel, C., Thomsen, Simon Francis, Avgustinova, A., Benitah, S. A., Lovato, P., Norsgaard, H., Mortensen, M. S., Veng, L., Rozell, B. & Brakebusch, Cord Herbert, 2018, In: Nature Communications. 9, 1, p. 1-18 18 p., 1420.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation

    Martínez-Sánchez, L. D. C., Ngo, P. A., Pradhan, R., Becker, L-S., Boehringer, D., Soteriou, D., Kubankova, M., Schweitzer, C., Koch, T., Thonn, V., Erkert, L., Stolzer, I., Günther, C., Becker, C., Weigmann, B., Klewer, M., Daniel, C., Amann, K., Tenzer, S., Atreya, R. & 8 others, Bergo, M., Brakebusch, Cord Herbert, Watson, A. J. M., Guck, J., Fabry, B., Atreya, I., Neurath, M. F. & López-Posadas, R., 2023, In: Gut. 72, 2, p. 275-294 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development.

    Benninger, Y., Thurnherr, T., Pereira, J. A., Krause, S., Wu, X., Chrostek-Grashoff, A., Herzog, D., Nave, K., Franklin, R. J. M., Meijer, D., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2007, In: Journal of Cell Biology. 177, 6, p. 1051-61 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1

    Huelsenbeck, S. C., Roggenkamp, D., May, M., Huelsenbeck, J., Brakebusch, Cord Herbert, Rottner, K., Ladwein, M., Just, I., Fritz, G., Schmidt, G. & Genth, H., Aug 2013, In: International Journal of Biochemistry & Cell Biology. 45, 8, p. 1767-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Expression of the 90K immunostimulator gene is controlled by a promoter with unique features.

    Brakebusch, Cord Herbert, Jallal, B., Fusco, O., Iacobelli, S. & Ullrich, A., 1997, In: Journal of Biological Chemistry. 272, 6, p. 3674-82 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    FMNL formins boost lamellipodial force generation

    Kage, F., Winterhoff, M., Dimchev, V., Mueller, J., Thalheim, T., Freise, A., Brühmann, S., Kollasser, J., Block, J., Dimchev, G. A., Geyer, M., Schnittler, H., Brakebusch, Cord Herbert, Stradal, T. E. B., Carlier, M., Sixt, M., Käs, J., Faix, J. & Rottner, K., 22 Mar 2017, In: Nature Communications. 8, 16 p., 14832.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

    Kage, F., Steffen, A., Ellinger, A., Ranftler, C., Gehre, C., Brakebusch, Cord Herbert, Pavelka, M., Stradal, T. & Rottner, K., 1 Dec 2017, In: Scientific Reports. 7, 1, 17 p., 9791.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    FMNL2 drives actin-based protrusion and migration downstream of Cdc42

    Block, J., Breitsprecher, D., Kühn, S., Winterhoff, M., Kage, F., Geffers, R., Duwe, P., Rohn, J. L., Baum, B., Brakebusch, Cord Herbert, Geyer, M., Stradal, T. E. B., Faix, J. & Rottner, K., 5 Jun 2012, In: Current Biology. 22, 11, p. 1005-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 5296