Bo Torben Porse

Bo Torben Porse

Professor, Clinical Professor

Member of:

  • Internal Medicine: Haematology

ORCID: 0000-0001-6043-0844

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  1. Published

    Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

    Pasini, D., Malatesta, M., Jung, H. R., Valfridsson, J. O. A., Willer, A., Olsson, L., Skotte, J., Wutz, A., Porse, Bo Torben, Jensen, O. N. & Helin, K., Aug 2010, In: Nucleic Acids Research. 38, 15, p. 4958-69 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients

    Rapin, N. P. J., Bagger, F. O., Jendholm, L. J., Mora-Jensen, H., Krogh, Anders, Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, Ole, Theilgaard-Mønch, Kim & Porse, Bo Torben, 6 Feb 2014, In: Blood (online). 123, 6, p. 894-904 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

    Lauridsen, F. K., Jensen, T. L., Rapin, N., Aslan, D., Wilhelmson, Anna, Pundhir, Sachin, Rehn, M., Paul, F., Giladi, A., Hasemann, M. S., Serup, Palle, Amit, I. & Porse, Bo Torben, 2018, In: Cell Reports. 24, 3, p. 766-780 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.

    Porse, Bo Torben, Kirillov, S. V., Awayez, M. J., Ottenheijm, H. C. & Garrett, R. A., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 16, p. 9003-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Disease evolution and outcomes in familial AML with germline CEBPA mutations

    Tawana, K., Wang, J., Renneville, A., Bödör, C., Hills, R., Loveday, C., Savic, A., Van Delft, F. W., Treleaven, J., Georgiades, P., Uglow, E., Asou, N., Uike, N., Debeljak, M., Jazbec, J., Ancliff, P., Gale, R., Thomas, X., Mialou, V., Döhner, K. & 21 others, Bullinger, L., Mueller, B., Pabst, T., Stelljes, M., Schlegelberger, B., Wozniak, E., Iqbal, S., Okosun, J., Araf, S., Frank, Anne-Katrine, Lauridsen, F. B., Porse, Bo Torben, Nerlov, C., Owen, C., Dokal, I., Gribben, J., Smith, M., Preudhomme, C., Chelala, C., Cavenagh, J. & Fitzgibbon, J., 3 Sep 2015, In: Blood. 126, 10, p. 1214-23 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo.

    Pedersen, T. A., Bereshchenko, O., Garcia-Silva, S., Ermakova, O., Kurz, E., Mandrup, S., Porse, Bo Torben & Nerlov, C., 2007, In: EMBO Journal. 26, 4, p. 1081-93 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Dynamic intron retention modulates gene expression in the monocytic differentiation pathway

    Song, R., Tikoo, S., Jain, R., Pinello, N., Au, A. Y. M., Nagarajah, R., Porse, Bo Torben, Rasko, J. E. J. & J.-L. Wong, J., 2022, In: Immunology. 165, 2, p. 274-286

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.

    Porse, Bo Torben, Pedersen TA, Xu, X., Lindberg, B., Wewer, Ulla M., Friis-Hansen, L. & Nerlov, C., 2001, In: Cell. 107, 2, p. 247-58 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination

    Søndergaard, E., Rauch, A., Michaut, Magali, Rapin, N., Rehn, M., Wilhelmson, Anna, Camponeschi, A., Hasemann, M. S., Bagger, F. O., Jendholm, J., Knudsen, K. J., Mandrup, S., Mårtensson, I. L. & Porse, Bo Torben, 26 Nov 2019, In: Cell Reports. 29, 9, p. 2756-2769.e6 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of IL9 during Allergic Lung Inflammation

    Kharwadkar, R., Ulrich, B. J., Chu, M., Koh, B., Hufford, M. M., Fu, Y., Birdsey, G. M., Porse, Bo Torben, Randi, A. M. & Kaplan, M. H., 2023, In: Journal of Immunology. 210, 5, p. 537-546

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation

    Knudsen, K. J., Rehn, M. C., Hasemann, M. S., Rapin, N. P. J., Bagger, F. O., Ohlsson, E. K., Willer, A., Frank, Anne-Katrine, Søndergaard, E., Jendholm, L. J., Thorén, L. A. M., Lee, J., Rak, J., Theilgaard-Mønch, Kim & Porse, Bo Torben, 2015, In: Genes & Development. 29, p. 1915-1929 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

    Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, Jens Vilstrup, Rapin, N. P. J., Porse, Bo Torben, Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice

    Christoffersen, C., Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlback, B. & Nielsen, L. B., 2008, In: Journal of Biological Chemistry. 283, 4, p. 1839-1847 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice

    Christoffersen, Christina, Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlbäck, B. & Nielsen, L. B., 25 Jan 2008, In: The Journal of Biological Chemistry. 283, 4, p. 1839-47 9 p.

    Research output: Contribution to journal › Journal article › Research

  15. Published

    Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis

    Grigoryan, A., Zacharaki, D., Balhuizen, A., Côme, C. R., Garcia, A. G., Hidalgo Gil, D., Frank, A. K., Aaltonen, K., Mañas, A., Esfandyari, J., Kjellman, P., Englund, E., Rodriguez, C., Sime, W., Massoumi, R., Kalantari, N., Prithiviraj, S., Li, Y., Dupard, S. J., Isaksson, H. & 4 others, Madsen, C. D., Porse, Bo Torben, Bexell, D. & Bourgine, P. E., 2022, In: Science Translational Medicine. 14, 666, 16 p., eabm6391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors

    Pundhir, Sachin, Bratt Lauridsen, F. K., Schuster, Mikkel Bruhn, Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N. P. J., Waage, J., Hasemann, M. S. & Porse, Bo Torben, 2018, In: Cell Reports. 23, 9, p. 2744-2757 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition

    Petrosius, V., Aragon-Fernandez, P., Üresin, Nil, Kovacs, G., Phlairaharn, T., Furtwängler, Benjamin, Op De Beeck, J., Skovbakke, S. L., Goletz, S., Thomsen, Simon Francis, Keller, U. A. D., Natarajan, K. N., Porse, Bo Torben & Schoof, E. M., 2023, In: Nature Communications. 14, 16 p., 5910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Gene expression profiling in MDS and AML: potential and future avenues

    Theilgaard-Mönch, K., Boultwood, J., Ferrari, S., Giannopoulos, K., Hernandez-Rivas, J. M., Kohlmann, A., Morgan, M., Porse, B., Tagliafico, E., Zwaan, C. M., Wainscoat, J., Van den Heuvel-Eibrink, M. M., Mills, K., Bullinger, L., Theilgaard-Mönch, K., Boultwood, J., Ferrari, S., Giannopoulos, K., Hernandez-Rivas, J. M., Kohlmann, A. & 8 others, Morgan, M., Porse, Bo Torben, Tagliafico, E., Zwaan, C. M., Wainscoat, J., Van den Heuvel-Eibrink, M. M., Mills, K. & Bullinger, L., 2011, In: Leukemia. 25, 6, p. 909-20 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

    Hansen, A. M., Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, J. S., Kalvisa, A., Tapia, Marta Cecylia, Gordon, Sandra, Ambri, F., Bagger, F. O., Pandey, D., Helin, K. & Porse, Bo Torben, 2022, In: Science Advances. 8, 11, eabf8627.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.

    Theilgaard-Mønch, Kim, Jacobsen, L. C., Nielsen, M. J., Rasmussen, T., Udby, L., Gharib, M., Arkwright, P. D., Gombart, A. F., Calafat, J., Moestrup, S. K., Porse, Bo Torben & Borregaard, N., 2006, In: Blood. 108, 1, p. 353-61 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis

    Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Thorén, L. A. M., Jendholm, L. J., Winther, Ole & Porse, Bo Torben, 2013, In: Nucleic Acids Research. 41, Database issue, p. D1034-D1039 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis

    Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Jendholm, L. J., Winther, O. & Porse, Bo Torben, 2012, In: Blood. 119, 26, p. 6394-6395 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  23. Published

    Heterozygous loss of Srp72 in mice is not associated with major hematological phenotypes

    D'Altri, T., Schuster, Mikkel Bruhn, Wenzel, Anne & Porse, Bo Torben, 2019, In: European Journal of Haematology. 103, 4, p. 319-328 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils.

    Theilgaard-Mønch, Kim, Jacobsen, L. C., Rasmussen, T., Niemann, C. U., Udby, L., Borup, R., Gharib, M., Arkwright, P. D., Gombart, A. F., Calafat, J., Porse, Bo Torben & Borregaard, N., 2005, In: Journal of Leukocyte Biology. 78, 2, p. 462-70 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

    Reckzeh, K., Kizilkaya, Hüsün Sheyma, Helbo, A. S., Estruch Alrich, Montserrat, Deslauriers, A. G., Grover, A., Rapin, N., Asmar, F., Grønbæk, Kirsten, Porse, Bo Torben, Borregaard, N., Vestweber, D., Nerlov, C. & Theilgaard-Mønch, Kim, 2018, In: Blood advances. 2, 13, p. 1628-1632 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4985646