Lena Specht

Lena Specht

Clinical Professor

Member of:

  • Clinical Oncology


  1. Published

    2-[18F]fluoro-2-deoxyglucose positron-emission tomography in staging, response evaluation, and treatment planning of lymphomas

    Specht, Lena & Specht, Lena, 1 Jul 2007, In: Seminars in Radiation Oncology. 17, 3, p. 190-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    18F-FDG PET imaging in detection of radiation-induced vascular disease in lymphoma survivors

    Ripa, R. S., Hag, Anne Mette Fisker, Knudsen, A., Loft, A., Specht, Lena & Kjær, Andreas, 2015, In: American Journal of Nuclear Medicine and Molecular Imaging. 5, 4, p. 408-415 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A clinical prognostic model compared to the newly adopted UICC staging in an independent validation cohort of P16 negative/positive head and neck cancer patients

    Rasmussen, J. H., Håkansson, K., Rasmussen, G. B., Vogelius, Ivan R. , Friborg, J., Fischer, Barbara Malene Bjerregaard, Bentzen, S. M. & Specht, Lena, 2018, In: Oral Oncology. 81, p. 52-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A comparison of loco-regional relapse pattern in HPV positive vs negative oropharyngeal cancers following radiotherapy: relation to pretreatment FDG-PET and radiotherapy target volumes

    Håkansson, K., Lindegaard, A. M., Bernsdorf, M., Gothelf, A., Kristensen, C. A., Specht, Lena, Friborg, Jeppe Tang & Vogelius, Ivan R. , 2023, In: Acta Oncologica. 62, 9, p. 1028-1035 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A failure-type specific risk prediction tool for selection of head-and-neck cancer patients for experimental treatments

    Håkansson, K., Rasmussen, J. H., Rasmussen, G. B., Friborg, J., Gerds, Thomas Alexander, Fischer, Barbara Malene Bjerregaard, L. Andersen, F., M. Bentzen, S., Specht, Lena & Vogelius, Ivan R. , Nov 2017, In: Oral Oncology. 74, p. 77-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A high and increasing HPV prevalence in tonsillar cancers in Eastern Denmark, 2000-2010: The largest registry-based study to date

    Garnaes, E., Kiss, K., Andersen, L., Therkildsen, M. H., Franzmann, M. B., Filtenborg-Barnkob, B., Høgdall, Estrid Vilma Solyom, Krenk, L., Josiassen, M., Lajer, C. B., Specht, Lena, Frederiksen, K., Friis-Hansen, Lennart Jan, Nielsen, Finn Cilius, Kjær, Susanne Krüger, Norrild, B. & von Buchwald, Christian, 1 May 2015, In: International journal of cancer. Journal international du cancer. 136, 9, p. 2196-203 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A new method to estimate doses to the normal tissues after past extended and involved field radiotherapy for Hodgkin lymphoma

    Maraldo, M. V., Lundemann, M., Vogelius, Ivan R. & Specht, Lena, Feb 2015, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 114, 2, p. 206-11 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A phase 2 trial of deep-inspiration breath hold in radiotherapy of gastric lymphomas

    Petersen, P. M., Rechner, L. A. & Specht, Lena, Apr 2022, In: Physics & imaging in radiation oncology. 22, p. 137-141 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A prospective, open-label study of low-dose total skin electron beam therapy in mycosis fungoides

    Kamstrup, M. R., Specht, Lena, Skovgaard, G. L., Gniadecki, R., Kamstrup, M. R., Specht, Lena, Skovgaard, G. L. & Gniadecki, R., 15 Jul 2008, In: International Journal of Radiation Oncology, Biology, Physics. 71, 4, p. 1204-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85

    Overgaard, J., Hansen, H. S., Overgaard, M., Bastholt, L., Berthelsen, A., Specht, Lena, Lindelov, B. & Jorgensen, K., 1998, In: Radiotherapy & Oncology. 46, 2, p. 135-146 11 p.

    Research output: Contribution to journalJournal articleResearch

  11. Published

    A step and shoot intensity modulated technique for total body irradiation

    Fog, L. S., Hansen, V. N., Kjær-kristoffersen, F., Berlon, T. E., Petersen, P. M., Mandeville, H. & Specht, Lena, 2019, In: Technical Innovations & Patient Support in Radiation Oncology. 10, p. 1-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A systematic review on clinical adaptive radiotherapy for head and neck cancer

    Lindegaard, A. M., Håkansson, K., Bernsdorf, M., Gothelf, A. B., Kristensen, C. A., Specht, Lena, Vogelius, Ivan R. & Friborg, Jeppe Tang, 2023, In: Acta oncologica (Stockholm, Sweden). 62, 11, p. 1360-1368 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    An extended hypofractionated palliative radiotherapy regimen for head and neck carcinomas

    Laursen, M., Specht, Lena, Kristensen, C. A., Gothelf, A., Bernsdorf, M., Vogelius, Ivan R. & Friborg, J., 2018, In: Frontiers in Oncology. 8, JUN, 8 p., 206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Antibody response to pneumococcal vaccine in patients with early stage Hodgkin's disease

    Frederiksen, B., Specht, Lena, Henrichsen, J., Pedersen, F. K. & Pedersen-Bjergaard, J., 1989, In: European Journal of Haematology. 43, 1, p. 45-49 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Artifacts in conventional computed tomography (CT) and free breathing four-dimensional CT induce uncertainty in gross tumor volume determination

    Persson, Gitte F., Nygaard, D. E., Af Rosenschöld, P. M., Richter Vogelius, I., Josipovic, M., Specht, Lena & Korreman, S. S., 1 Aug 2011, In: International Journal of Radiation Oncology, Biology, Physics. 80, 5, p. 1573-80 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Background and rationale for radiotherapy in early-stage Hodgkin lymphoma

    Specht, Lena & Ng, A., 2011, Radiotherapy for Hodgkin lymphoma. Specht, L. & Yahalom, J. (eds.). Berlin: Springer, p. 7-20 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. Published

    Baseline FDG PET/CT in free breathing versus deep inspiration breath-hold for pediatric patients with mediastinal lymphoma

    Lundgaard, A. Y., Dejanovic, D., Berthelsen, A. K., Andersen, Flemming Littrup, Rechner, L. A., Borgwardt, L., Hjalgrim, L. L., Specht, Lena & Maraldo, M. V., 2022, In: Acta Oncologica. 61, 2, p. 239-246 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Behandling ved tidlig Hodgkin's sygdom

    Specht, Lena, Carde, P., Mauch, P., Magrini, S. M. & Santarelli, M. T., 15 Nov 1993, In: Ugeskrift for Laeger. 155, 46, p. 3750-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Biological optimization for mediastinal lymphoma radiotherapy - a preliminary study

    Rechner, L. A., Modiri, A., Stick, L. B., Maraldo, M. V., Aznar, M. C., Rice, S. R., Sawant, A., Bentzen, S. M., Vogelius, Ivan R. & Specht, Lena, 27 Mar 2020, In: Acta Oncologica. 59, 8, p. 879-887 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Blodsygdomme.

    Borregaard, N., Andersen, M. K., Berthelsen, A. K., Bjerrum, O. W., Brown, P. D. N., Geisler, C., Gimsing, P., Hansen, M., Jurlander, J., Kjeldsen, L., Loft, A., Nielsen, O. J., Ralfkiær, E., Sengeløv, H. & Specht, Lena, 2009, Medicinsk Kompendium. 17. ed. København: Nyt Nordisk Forlag Arnold Busck, p. 1762-1887

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  21. Published

    Breathing adapted radiotherapy for breast cancer: comparison of free breathing gating with the breath-hold technique

    Korreman, S. S., Pedersen, A. N., Nøttrup, T. J., Specht, Lena & Nyström, H., 1 Sep 2005, In: Radiotherapy & Oncology. 76, 3, p. 311-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Breathing adapted radiotherapy of breast cancer: reduction of cardiac and pulmonary doses using voluntary inspiration breath-hold

    Pedersen, A. N., Korreman, S., Nyström, H. & Specht, Lena, 2004, In: Radiotherapy & Oncology. 72, 1, p. 53-60 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Brentuximab Vedotin Plus AVD for First-Line Treatment of Early-Stage Unfavorable Hodgkin Lymphoma (BREACH): A Multicenter, Open-Label, Randomized, Phase II Trial

    Fornecker, L. M., Lazarovici, J., Aurer, I., Casasnovas, R. O., Gac, A. C., Bonnet, C., Bouabdallah, K., Feugier, P., Specht, L., Molina, L., Touati, M., Borel, C., Stamatoullas, A., Nicolas-Virelizier, E., Pascal, L., Lugtenburg, P., Di Renzo, N., Vander Borght, T., Traverse-Glehen, A., Dartigues, P. & 5 others, Hutchings, M., Versari, A., Meignan, M., Federico, M. & André, M., 2023, In: Journal of Clinical Oncology. 41, 2, p. 327-335 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    CBCT is not valid for response evaluation after chemoradiotherapy for locally advanced NSCLC

    Persson, Gitte F., Pohl, M., Nygard, L., De Blanck, S. R., Scherman, J., Langer, Seppo W., Larsen, Klaus Richter, Clementsen, P. F., Specht, Lena, Fischer, Barbara Malene Bjerregaard, Aznar, M. C. & Josipovic, Mirjana, 2019, In: Radiotherapy & Oncology. 133, S1, p. S398-S399 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  25. Published

    Can audio coached 4D CT emulate free breathing during the treatment course?

    Persson, G. F., Nygaard, D. E., Olsen, M., Juhler-Nøttrup, T., Pedersen, A. N., Specht, Lena, Korreman, S. S., Persson, Gitte F., Nygaard, D. E., Olsen, M., Juhler-Nøttrup, T., Pedersen, A. N., Specht, Lena & Korreman, S., 1 Jan 2008, In: Acta Oncologica. 47, 7, p. 1397-405 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Cardiac Lymphoma, a Challenging Extranodal Lymphoma

    Specht, Lena, 2020, In: International Journal of Radiation Oncology Biology Physics. 106, 3, 1 p.

    Research output: Contribution to journalLetterResearchpeer-review

  27. Published

    Cardiac and pulmonary complication probabilities for breast cancer patients after routine end-inspiration gated radiotherapy

    Korreman, S. S., Pedersen, A. N., Josipovic, M., Aarup, L. R., Juhler-Nøttrup, T., Specht, Lena, Nyström, H., Josipovic, M., Josipovic, M., Josipovic, M., Josipovic, M., Josipovic, M., Josipovic, M., Josipovic, M., Josipovic, M., Aarup, L. R. & Josipović, M., 1 Aug 2006, In: Radiotherapy & Oncology. 80, 2, p. 257-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Cardiovascular disease after treatment for Hodgkin's lymphoma: an analysis of nine collaborative EORTC-LYSA trials

    Maraldo, M. V., Giusti, F., Vogelius, Ivan R. , Jensen, M. L., van der Kaaij, M. A. E., Ramadan, S., Meulemans, B., Henry-Amar, M., Aleman, B. M. P., Raemaekers, J., Meijnders, P., Moser, E. C., Kluin-Nelemans, H. C., Feugier, P., Casasnovas, O., Fortpied, C. & Specht, Lena, 1 Nov 2015, In: Lancet Haematology. 2, 11, p. E492-E502

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Cardiovascular risk factors, radiation therapy, and myocardial infarction among lymphoma survivors

    Salz, T., Zabor, E. C., Brown, Peter de Nully, Dalton, Susanne Oksbjerg, Raghunathan, N. J., Matasar, M. J., Steingart, R., Hjalgrim, Henrik, Specht, Lena, Vickers, A. J., Oeffinger, K. C. & Johansen, Christoffer, 2022, In: Acta Oncologica. 61, 9, p. 1064-1068

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Accepted/In press

    Career development: A balance of opportunities and choices

    de Jong, D., Kimby, E. & Specht, Lena, 2024, (Accepted/In press) In: Hematological Oncology. p. 1-4

    Research output: Contribution to journalComment/debateResearchpeer-review

  31. Published

    Centraliseret efterkontrol af patienter behandlet for hoved-halskraeft

    Grau, C., Specht, Lena, Hansen, H. S., Overgaard, M. & Overgaard, J., 17 Feb 1997, In: Ugeskrift for Laeger. 159, 8, p. 1104-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Changes over the course of time in histological subclassification of Hodgkin's disease in Denmark

    Lauritzen, A. F., Specht, Lena, Nissen, N. I. & Hou-Jensen, K., 1991, In: Danish Medical Bulletin. 38, 1, p. 84-87 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Chemotherapeutic treatment is associated with Notch1 induction in cutaneous T-cell lymphoma

    Kamstrup, M. R., Biskup, E., Manfè, V., Savorani, C., Liszewski, W., Wirén, J., Specht, Lena & Gniadecki, R., Jan 2017, In: Leukemia and Lymphoma. 58, 1, p. 171-178 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Chemotherapy alone versus chemotherapy plus radiotherapy for adults with early stage Hodgkin lymphoma (Review)

    Blank, O., von Tresckow, B., Monsef, I., Specht, Lena, Engert, A. & Skoetz, N., 2017, In: Cochrane Database of Systematic Reviews. 4, 139 p., CD007110.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Chemotherapy alone versus chemotherapy plus radiotherapy for early stage Hodgkin lymphoma

    Herbst, C., Rehan, F. A., Skoetz, N., Bohlius, J., Brillant, C., Schulz, H., Monsef, I., Specht, Lena & Engert, A., 1 Jan 2011, In: Cochrane Database of Systematic Reviews. 2, p. CD007110

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Chemotherapy, radiotherapy and combined modality for Hodgkin's disease, with emphasis on second cancer risk

    Franklin, J. G., Paus, M. D., Pluetschow, A., Specht, Lena, Franklin, J. G., Paus, M. D., Pluetschow, A. & Specht, Lena, 1 Jan 2005, In: Cochrane Database of Systematic Reviews. 4, p. CD003187

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Clinical impact of FDG-PET/CT in the planning of radiotherapy for early-stage Hodgkin lymphoma

    Hutchings, M., Loft, A., Hansen, M., Berthelsen, A. K., Specht, Lena, Hutchings, M., Jakobsen, A. L., Hansen, M., Berthelsen, A. K. & Specht, Lena, 1 Mar 2007, In: European Journal of Haematology. 78, 3, p. 206-12 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Combined modality treatment improves tumor control and overall survival in patients with early stage Hodgkin's lymphoma: a systematic review

    Herbst, C., Rehan, F. A., Brillant, C., Bohlius, J., Skoetz, N., Schulz, H., Monsef, I., Specht, Lena, Engert, A., Herbst, C., Rehan, F. A., Brillant, C., Bohlius, J., Skoetz, N., Schulz, H., Monsef, I., Specht, Lena & Engert, A., 1 Mar 2010, In: Haematologica. 95, 3, p. 494-500 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Consolidation radiotherapy may improve outcomes in people with Hodgkin's disease achieving complete remission after combination chemotherapy

    Specht, Lena, 2004, In: Cancer Treatment Reviews. 30, 5, p. 479-82 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Construction of a pathological risk model of occult lymph node metastases for prognostication by semi-automated image analysis of tumor budding in early-stage oral squamous cell carcinoma

    Pedersen, N. J., Jensen, D. H., Lelkaitis, G., Kiss, K., Charabi, Birgitte Wittenborg, Specht, Lena & von Buchwald, Christian, Feb 2017, In: OncoTarget. 8, 11, p. 18227-18237 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Continuing rise in oropharyngeal cancer in a high HPV prevalence area: A Danish population-based study from 2011 to 2014

    Carlander, A. F., Larsen, C. G., Jensen, D. H., Garnaes, E., Kiss, K., Andersen, L., Olsen, C. H., Franzmann, M., Høgdall, Estrid Vilma Solyom, Kjær, Susanne Krüger, Norrild, B., Specht, Lena, Andersen, E., Hansen, T. V. O., Nielsen, Finn Cilius & von Buchwald, Christian, Jan 2017, In: European Journal of Cancer. 70, p. 75-82

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Coplanar and non-coplanar VMAT facilitate OAR dose sparing in central lung SBRT

    Thomsen, J. B., Persson, Gitte F., Aznar, M. C., Berthelsen, A. K., Specht, Lena & Josipovic, Mirjana, 20 Apr 2018, In: Radiotherapy & Oncology. 127, Supp.1, p. S1021-S1021 EP-1886.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. Published

    Correlation between HPV status at T and N sites of oropharyngeal squamous cell carcinomas

    Josiassen, M. V., Charabi, Birgitte Wittenborg, Lajer, C. B., Garnaes, E., Hamilton Therkildsen, M., Norrild, B., Specht, Lena, Nielsen, Finn Cilius & von Buchwald, Christian, Dec 2017, In: Acta Oto-Laryngologica. 137, 12, p. 1260-1264 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Cutaneous Lymphomas

    Specht, Lena & Skov, L., 2019, In: Clinical Oncology. 31, 11, p. 797-807 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    DAHANCA 10: Effect of darbepoetin alfa and radiotherapy in the treatment of squamous cell carcinoma of the head and neck. A multicenter, open-label, randomized, phase 3 trial by the Danish head and neck cancer group

    Overgaard, J., Hoff, C. M., Hansen, H. S., Specht, Lena, Overgaard, M., Lassen, P., Andersen, E., Johansen, J., Andersen, L. J., Evensen, J. F., Alsner, J. & Grau, C., 2018, In: Radiotherapy & Oncology. 127, 1, p. 12-19

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Deep Inspiration Breath Hold Compliance in Radiation Therapy for Locally Advanced Lung Cancer

    Persson, G. F., Aznar, M. C., Rydhog, J. S., Mortensen, S. R., Nygaard, L., Pohl, M., Langer, S. W., Specht, Lena & Josipovic, Mirjana, 1 Oct 2017, In: International Journal of Radiation Oncology, Biology, Physics. 99, 2, Supp., p. E491-E491

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  47. Published

    Deep inspiration breath hold and locally advanced lung cancer: validation of geometrical uncertainties

    Josipovic, M., Aznar, M., Damkjær, S., Thomsen, J., Rydhög, J., Nygård, L., Specht, Lena, Pøhl, M. & Persson, Gitte F., 2018, In: Radiotherapy and Oncology. 127, Supplement 1, p. S1102-S1103 EP-2020.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    Deep inspiration breath hold in locally advanced lung cancer radiotherapy: validation of intrafractional geometric uncertainties in the INHALE trial

    Josipovic, Mirjana, Aznar, M. C., Thomsen, J. B., Scherman, J., Damkjaer, S., Nygard, L., Specht, Lena, Pohl, M. & Persson, Gitte F., 2019, In: British Journal of Radiology. 92, 1104, 10 p., 20190569.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Deep inspiration breath hold radiotherapy for locally advanced lung cancer: Comparison of different treatment techniques on target coverage, lung dose and treatment delivery time

    Josipovic, Mirjana, Persson, Gitte F., Hakansson, K., Bangsgaard, J. P., Damkjær, S. M., Westman, G., Specht, Lena & Aznar, M. C., 1 Oct 2013, In: Acta Oncologica. 52, 7, p. 1582-1586

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Deep inspiration breath-hold radiotherapy for lung cancer: impact on image quality and registration uncertainty in cone beam CT image guidance

    Josipovic, Mirjana, Persson, Gitte F., Bangsgaard, J. P., Specht, Lena & Aznar, M. C., 17 Jun 2016, In: British Journal of Radiology. 89, 1068, 20160544.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 917341