Ruth Loos

Ruth Loos

Professor

  • Loos Group

    Blegdamsvej 3B, Mærsk Tårnet, 7. sal

    2200 København N.

    Phone: +4535337781Mobile: +4530589681
ORCID: 0000-0002-8532-5087

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  1. Published

    A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies

    Li, X., Chen, H., Selvaraj, M. S., Van Buren, E., Zhou, H., Wang, Y., Sun, R., McCaw, Z. R., Yu, Z., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Brody, J. A., Cade, B. E., Carson, A. P., Carlson, J. C., Chami, N., Chen, Y-D. I. & 31 others, Curran, J. E., de Vries, P. S., Fornage, M., Franceschini, N., Freedman, B. I., Gu, C., Heard-Costa, N. L., He, J., Hou, L., Hung, Y., Irvin, M. R., Kaplan, R. C., Kardia, S. L. R., Kelly, T., Konigsberg, I., Kooperberg, C., Kral, B. G., Li, C., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Palmer, N. D., Peyser, P. A., Psaty, B. M., Raffield, L. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, bioRxiv, 71 p.

    Research output: Working paper › Preprint › Research

  2. Published

    Ancestral diversity in lipoprotein(a) studies helps address evidence gaps

    Lee, M. P., Dimos, S. F., Raffield, L. M., Wang, Z., Ballou, A. F., Downie, C. G., Arehart, C. H., Correa, A., De Vries, P. S., Du, Z., Gignoux, C. R., Gordon-Larsen, P., Guo, X., Haessler, J., Howard, A. G., Hu, Y., Kassahun, H., Kent, S. T., Lopez, J. A. G., Monda, K. L. & 14 others, North, K. E., Peters, U., Preuss, M. H., Rich, S. S., Rhodes, S. L., Yao, J., Yarosh, R., Tsai, M. Y., Rotter, J. I., Kooperberg, C. L., Loos, Ruth, Ballantyne, C., Avery, C. L. & Graff, M., 2023, In: Open Heart. 10, 2, 11 p., e002382.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Approaches to addressing the rise in obesity levels

    Apovian, C. M., Guo, X. R., Hawley, J. A., Karmali, S., Loos, Ruth & Waterlander, W. E., 2023, In: Nature Reviews Endocrinology. 19, p. 76-81

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Discrepancy between predicted and measured exercise intensity for eliciting the maximal rate of lipid oxidation

    Kittrell, H. D., DiMenna, F. J., Arad, A. D., Oh, W., Hofer, I., Walker, R. W., Loos, Ruth, Albu, J. B. & Nadkarni, G. N., 2023, In: Nutrition, Metabolism and Cardiovascular Diseases. 33, 11, p. 2189-2198

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Distilling causality between physical activity traits and obesity via Mendelian randomization

    Wang, Z., Davey Smith, G., Loos, Ruth & den Hoed, M., 2023, In: Communications Medicine. 3, 6 p., 173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Early-life residential green spaces and traffic exposure in association with young adult body composition: a longitudinal birth cohort study of twins

    Figaroa, M. N. S., Gielen, M., Casas, L., Loos, Ruth, Derom, C., Weyers, S., Nawrot, T. S., Zeegers, M. P. & Bijnens, E. M., 2023, In: Environmental Health. 22, 13 p., 18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations

    Gerhart-Hines, Zach & Loos, Ruth, 2023, In: Current Opinion in Genetics and Development. 83, 102117.

    Research output: Contribution to journal › Editorial › Research

  8. Published

    GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

    Lagou, V., Jiang, L., Ulrich, A., Zudina, L., González, K. S. G., Balkhiyarova, Z., Faggian, A., Maina, J. G., Chen, S., Todorov, P. V., Sharapov, S., David, A., Marullo, L., Mägi, R., Rujan, R. M., Ahlqvist, E., Thorleifsson, G., Gao, Η., Εvangelou, Ε., Benyamin, B. & 78 others, Scott, R. A., Isaacs, A., Zhao, J. H., Willems, S. M., Johnson, T., Gieger, C., Grallert, H., Meisinger, C., Müller-Nurasyid, M., Strawbridge, R. J., Goel, A., Rybin, D., Albrecht, E., Jackson, A. U., Stringham, H. M., Corrêa, I. R., Farber-Eger, E., Steinthorsdottir, V., Uitterlinden, A. G., Munroe, P. B., Brown, M. J., Schmidberger, J., Holmen, O., Thorand, B., Hveem, K., Wilsgaard, T., Mohlke, K. L., Wang, Z., den Hoed, M., Shmeliov, A., den Hoed, M., Loos, Ruth, Kratzer, W., Haenle, M., Koenig, W., Boehm, B. O., Tan, T. M., Tomas, A., Salem, V., Barroso, I., Tuomilehto, J., Boehnke, M., Florez, J. C., Hamsten, A., Watkins, H., Njølstad, I., Wichmann, H. E., Caulfield, M. J., Khaw, K. T., van Duijn, C. M., Hofman, A., Wareham, N. J., Langenberg, C., Whitfield, J. B., Martin, N. G., Montgomery, G., Scapoli, C., Tzoulaki, I., Elliott, P., Thorsteinsdottir, U., Stefansson, K., Brittain, E. L., McCarthy, M. I., Froguel, P., Sexton, P. M., Wootten, D., Groop, L., Dupuis, J., Meigs, J. B., Deganutti, G., Demirkan, A., Pers, Tune H, Reynolds, C. A., Aulchenko, Y. S., Kaakinen, M. A., Jones, B., Prokopenko, I. & van Duijn, C. M., 2023, In: Nature Genetics. 55, 9, p. 1448-1461 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Genetic insights into resting heart rate and its role in cardiovascular disease

    van de Vegte, Y. J., Eppinga, R. N., van der Ende, M. Y., Hagemeijer, Y. P., Mahendran, Y., Salfati, E., Smith, A. V., Tan, V. Y., Arking, D. E., Ntalla, I., Appel, E. V., Schurmann, C., Brody, J. A., Rueedi, R., Polasek, O., Sveinbjornsson, G., Lecoeur, C., Ladenvall, C., Zhao, J. H., Isaacs, A. & 31 others, Wang, L., Luan, J., Hwang, S. J., Mononen, N., Auro, K., Jackson, A. U., Bielak, L. F., Zeng, L., Shah, N., Nethander, M., Campbell, A., Rankinen, T., Pechlivanis, S., Qi, L., Zhao, W., Rizzi, F., Tanaka, T., Robino, A., Cocca, M., Lange, L., Müller-Nurasyid, M., Roselli, C., Zhang, W., Kleber, M. E., Witte, D. R., Linneberg, Allan René, Lind, L., Hansen, Torben, Grarup, Niels, Loos, Ruth & DCCT/EDIC Research Group, D. R. G., 2023, In: Nature Communications. 14, 4646.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Genome-Wide Polygenic Risk Score for CKD in Individuals with APOL1 High-Risk Genotypes

    Vy, H. M. T., Coca, S. G., Sawant, A., Sakhuja, A., Gutierrez, O. M., Cooper, R., Loos, Ruth, Horowitz, C. R., Do, R. & Nadkarni, G. N., 2023, In: Clinical Journal of American Society of Nephrology. .

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

    Kiryluk, K., Sanchez-Rodriguez, E., Zhou, X. J., Zanoni, F., Liu, L., Mladkova, N., Khan, A., Marasa, M., Zhang, J. Y., Balderes, O., Sanna-Cherchi, S., Bomback, A. S., Canetta, P. A., Appel, G. B., Radhakrishnan, J., Trimarchi, H., Sprangers, B., Cattran, D. C., Reich, H., Pei, Y. & 168 others, Ravani, P., Galesic, K., Maixnerova, D., Tesar, V., Stengel, B., Metzger, M., Canaud, G., Maillard, N., Berthoux, F., Berthelot, L., Pillebout, E., Monteiro, R., Nelson, R., Wyatt, R. J., Smoyer, W., Mahan, J., Samhar, A. A., Hidalgo, G., Quiroga, A., Weng, P., Sreedharan, R., Selewski, D., Davis, K., Kallash, M., Vasylyeva, T. L., Rheault, M., Chishti, A., Ranch, D., Wenderfer, S. E., Samsonov, D., Claes, D. J., Akchurin, O., Goumenos, D., Stangou, M., Nagy, J., Kovacs, T., Fiaccadori, E., Amoroso, A., Barlassina, C., Cusi, D., Del Vecchio, L., Battaglia, G. G., Bodria, M., Boer, E., Bono, L., Boscutti, G., Caridi, G., Lugani, F., Ghiggeri, G. M., Coppo, R., Peruzzi, L., Esposito, V., Esposito, C., Feriozzi, S., Polci, R., Frasca, G., Galliani, M., Garozzo, M., Mitrotti, A., Gesualdo, L., Granata, S., Zaza, G., Londrino, F., Magistroni, R., Pisani, I., Magnano, A., Marcantoni, C., Messa, P., Mignani, R., Pani, A., Ponticelli, C., Roccatello, D., Salvadori, M., Salvi, E., Santoro, D., Gembillo, G., Savoldi, S., Spotti, D., Zamboli, P., Izzi, C., Alberici, F., Delbarba, E., Florczak, M., Krata, N., Mucha, K., Pączek, L., Niemczyk, S., Moszczuk, B., Pańczyk-Tomaszewska, M., Mizerska-Wasiak, M., Perkowska-Ptasińska, A., Bączkowska, T., Durlik, M., Pawlaczyk, K., Sikora, P., Zaniew, M., Kaminska, D., Krajewska, M., Kuzmiuk-Glembin, I., Heleniak, Z., Bullo-Piontecka, B., Liberek, T., Dębska-Slizien, A., Hryszko, T., Materna-Kiryluk, A., Miklaszewska, M., Szczepańska, M., Dyga, K., Machura, E., Siniewicz-Luzeńczyk, K., Pawlak-Bratkowska, M., Tkaczyk, M., Runowski, D., Kwella, N., Drożdż, D., Habura, I., Kronenberg, F., Prikhodina, L., van Heel, D., Fontaine, B., Cotsapas, C., Wijmenga, C., Franke, A., Annese, V., Gregersen, P. K., Parameswaran, S., Weirauch, M., Kottyan, L., Harley, J. B., Suzuki, H., Narita, I., Goto, S., Lee, H., Kim, D. K., Kim, Y. S., Park, J. H., Cho, B. L., Choi, M., Van Wijk, A., Huerta, A., Ars, E., Ballarin, J., Lundberg, S., Vogt, B., Mani, L. Y., Caliskan, Y., Barratt, J., Abeygunaratne, T., Kalra, P. A., Gale, D. P., Panzer, U., Rauen, T., Floege, J., Schlosser, P., Ekici, A. B., Eckardt, K. U., Chen, N., Xie, J., Lifton, R. P., Loos, Ruth, Kenny, E. E., Ionita-Laza, I., Köttgen, A., Julian, B. A., Novak, J., Scolari, F., Zhang, H. & Gharavi, A. G., 2023, In: Nature Genetics. 55, 7, p. 1091-1105 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Genomic Disorders in CKD across the Lifespan

    Verbitsky, M., Krishnamurthy, S., Krithivasan, P., Hughes, D., Khan, A., Marasà, M., Vena, N., Khosla, P., Zhang, J., Lim, T. Y., Glessner, J. T., Weng, C., Shang, N., Shen, Y., Hripcsak, G., Hakonarson, H., Ionita-Laza, I., Levy, B., Kenny, E. E., Loos, R. J. F. & 11 others, Kiryluk, K., Sanna-Cherchi, S., Crosslin, D. R., Furth, S., Warady, B. A., Igo, R. P., Iyengar, S. K., Wong, C. S., Parsa, A., Feldman, H. I. & Gharavi, A. G., 2023, In: Journal of the American Society of Nephrology : JASN. 34, 4, p. 607-618 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

    Wang, Y., Namba, S., Lopera-Maya, E. A., Kerminen, S., Tsuo, K., Läll, K., Kanai, M., Zhou, W., Wu, K. H. H., Favé, M. J., Bhatta, L., Awadalla, P., Brumpton, B. M., Deelen, P., Hveem, K., Lo Faro, V., Mägi, R., Murakami, Y., Sanna, S., Smoller, J. W. & 49 others, Uzunovic, J., Wolford, B. N., Wu, K. H. H., Rasheed, H., Hirbo, J. B., Bhattacharya, A., Zhao, H., Surakka, I., Lopera-Maya, E. A., Chapman, S. B., Karjalainen, J., Kurki, M., Mutaamba, M., Partanen, J. J., Brumpton, B. M., Chavan, S., Chen, T. T., Daya, M., Ding, Y., Feng, Y. C. A., Gignoux, C. R., Graham, S. E., Hornsby, W. E., Ingold, N., Johnson, R., Laisk, T., Lin, K., Lv, J., Millwood, I. Y., Loos, Ruth, BBJ, B., BioMe, B., BioVU, B., Canadian Partnership for Tomorrow's Health/OHS, C. P. F. T. H., China Kadoorie Biobank Collaborative Group, C. K. B. C. G., Colorado Center for Personalized Medicine, C. C. F. P. M., deCODE Genetics, D. G., ESTBB, E., FinnGen, F., Generation Scotland, G. S., Genes & Health, G. &. H., LifeLines, L., Mass General Brigham Biobank, M. G. B. B., Michigan Genomics Initiative, M. G. I., QIMR Berghofer Biobank, Q. B. B., Taiwan Biobank, T. B., The HUNT Study, T. H. S., UCLA ATLAS Community Health Initiative, U. A. C. H. I. & UKBB, U., 2023, In: Cell Genomics. 3, 1, 18 p., 100241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 17 p., 133.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores

    Hrytsenko, Y., Shea, B., Elgart, M., Kurniansyah, N., Lyons, G., Morrison, A. C., Carson, A. P., Haring, B., Mitchel, B. D., Psaty, B. M., Jaeger, B. C., Gu, C. C., Kooperberg, C., Levy, D., Lloyd-Jones, D., Choi, E., Brody, J. A., Smith, J. A., Rotter, J. I., Moll, M. & 18 others, Fornage, M., Simon, N., Castaldi, P., Casanova, R., Chung, R., Kaplan, R., Loos, Ruth, Kardia, S. L. R., Rich, S. S., Redline, S., Kelly, T., O'Connor, T., Zhao, W., Kim, W., Guo, X., Chen, Y. D. I., Sofer, T. & Trans-Omics in Precision Medicine Consortium, T. I. P. M. C., 2023, medRxiv, 41 p.

    Research output: Working paper › Preprint › Research

  16. Published

    Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing

    Jakubek, Y. A., Zhou, Y., Stilp, A., Bacon, J., Wong, J. W., Ozcan, Z., Arnett, D., Barnes, K., Bis, J. C., Boerwinkle, E., Brody, J. A., Carson, A. P., Chasman, D. I., Chen, J., Cho, M., Conomos, M. P., Cox, N., Doyle, M. F., Fornage, M., Guo, X. & 31 others, Kardia, S. L. R., Lewis, J. P., Loos, Ruth, Ma, X., Machiela, M. J., Mack, T. M., Mathias, R. A., Mitchell, B. D., Mychaleckyj, J. C., North, K., Pankratz, N., Peyser, P. A., Preuss, M. H., Psaty, B., Raffield, L. M., Vasan, R. S., Redline, S., Rich, S. S., Rotter, J. I., Silverman, E. K., Smith, J. A., Smith, A. P., Taub, M., Taylor, K. D., Yun, J., Li, Y., Desai, P., Bick, A. G., Reiner, A. P., Scheet, P. & Auer, P. L., 2023, In: Nature Genetics. 55, 11, p. 1912-1919 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications

    VA Million Veteran Program, V. M. V. P., 2023, medRxiv, 39 p.

    Research output: Working paper › Preprint › Research

  18. Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome

    Barry, A., McNulty, M. T., Jia, X., Gupta, Y., Debiec, H., Luo, Y., Nagano, C., Horinouchi, T., Jung, S., Colucci, M., Ahram, D. F., Mitrotti, A., Sinha, A., Teeninga, N., Jin, G., Shril, S., Caridi, G., Bodria, M., Lim, T. Y., Westland, R. & 50 others, Zanoni, F., Marasa, M., Turudic, D., Giordano, M., Gesualdo, L., Magistroni, R., Pisani, I., Fiaccadori, E., Reiterova, J., Maringhini, S., Morello, W., Montini, G., Weng, P. L., Scolari, F., Saraga, M., Tasic, V., Santoro, D., van Wijk, J. A. E., Milošević, D., Kawai, Y., Kiryluk, K., Pollak, M. R., Gharavi, A., Lin, F., Simœs e Silva, A. C., Loos, Ruth, Kenny, E. E., Schreuder, M. F., Zurowska, A., Dossier, C., Ariceta, G., Drozynska-Duklas, M., Hogan, J., Jankauskiene, A., Hildebrandt, F., Prikhodina, L., Song, K., Bagga, A., Cheong, H., Ghiggeri, G. M., Vachvanichsanong, P., Nozu, K., Lee, D., Vivarelli, M., Raychaudhuri, S., Tokunaga, K., Sanna-Cherchi, S., Ronco, P., Iijima, K. & Sampson, M. G., 2023, In: Nature Communications. 14, 1, 2481.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program

    Small, A. M., Peloso, G. M., Linefsky, J., Aragam, J., Galloway, A., Tanukonda, V., Wang, L. C., Yu, Z., Sunitha Selvaraj, M., Farber-Eger, E. H., Baker, M. T., Setia-Verma, S., Lee, S. S. K., Preuss, M., Ritchie, M. D., Damrauer, S. M., Rader, D. J., Wells, Q. S., Loos, R., Lubitz, S. A. & 5 others, Thanassoulis, G., Cho, K., Wilson, P. W. F., Natarajan, P. & O'Donnell, C. J., 2023, In: Circulation. 147, 12, p. 942-955 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    New insights in the mechanisms of weight-loss maintenance: Summary from a Pennington symposium

    Flanagan, E. W., Spann, R., Berry, S. E., Berthoud, H. R., Broyles, S., Foster, G. D., Krakoff, J., Loos, Ruth, Lowe, M. R., Ostendorf, D. M., Powell-Wiley, T. M., Redman, L. M., Rosenbaum, M., Schauer, P. R., Seeley, R. J., Swinburn, B. A., Hall, K. & Ravussin, E., 2023, In: Obesity. 31, 12, p. 2895-2908

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes

    Yu, M., Aguirre, M., Jia, M., Gjoni, K., Cordova-Palomera, A., Munger, C., Amgalan, D., Rosa Ma, X., Pereira, A., Tcheandjieu, C., Seidman, C., Seidman, J., Tristani-Firouzi, M., Chung, W., Goldmuntz, E., Srivastava, D., Loos, R. J. F., Chami, N., Cordell, H., Dreßen, M. & 8 others, Mueller-Myhsok, B., Lahm, H., Krane, M., Pollard, K. S., Engreitz, J. M., Gagliano Taliun, S. A., Gelb, B. D. & Priest, J. R., 2023, In: Circulation: Genomic and Precision Medicine. 16, 3, p. 258-266 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    PFAS Exposures and the Human Metabolome: A Systematic Review of Epidemiological Studies

    India-Aldana, S., Yao, M., Midya, V., Colicino, E., Chatzi, L., Chu, J., Gennings, C., Jones, D. P., Loos, Ruth, Setiawan, V. W., Smith, M. R., Walker, R. W., Barupal, D., Walker, D. I. & Valvi, D., 2023, In: Current Pollution Reports. 9, p. 510-568

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms

    Deutsch, A. J., Stalbow, L., Majarian, T. D., Mercader, J. M., Manning, A. K., Florez, J. C., Loos, Ruth & Udler, M. S., 2023, In: Diabetes Care. 46, 4, p. 794-800 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Precision medicine in complex diseases - Molecular subgrouping for improved prediction and treatment stratification

    Johansson, Å., Andreassen, O. A., Brunak, Søren, Franks, P. W., Hedman, H., Loos, Ruth, Meder, B., Melén, E., Wheelock, C. E. & Jacobsson, B., 2023, In: Journal of Internal Medicine. 294, 4, p. 378-396 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study

    Wang, Y., Selvaraj, M. S., Li, X., Li, Z., Holdcraft, J. A., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Cade, B. E., Carlson, J. C., Carson, A. P., Chen, Y. D. I., Curran, J. E., de Vries, P. S., Dutcher, S. K., Ellinor, P. T., Floyd, J. S., Fornage, M. & 31 others, Freedman, B. I., Gabriel, S., Germer, S., Gibbs, R. A., Guo, X., He, J., Heard-Costa, N., Hildalgo, B., Hou, L., Irvin, M. R., Joehanes, R., Kaplan, R. C., Kardia, S. L., Kelly, T. N., Kim, R., Kooperberg, C., Kral, B. G., Levy, D., Li, C., Liu, C., Lloyd-Jone, D., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Murabito, J. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, In: American Journal of Human Genetics. 110, 10, p. 1704-1717 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Role of sociodemographic, clinical, behavioral, and molecular factors in precision prevention of type 2 diabetes: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD Precision Medicine in Diabetes Initiative, A. P. M. I. D. I., 2023, medRxiv.

    Research output: Working paper › Preprint › Research

  27. Published

    Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

    Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, Kahkoska, A. R., Kettunen, J. L. T., Kreienkamp, R. J., Lim, L. L., Männistö, J. M. E., Massey, R., Mclennan, N. M., Miller, R. G., Morieri, M. L., Most, J., Naylor, R. N., Ozkan, B., Patel, K. A., Pilla, S. J., Prystupa, K., Raghavan, S., Rooney, M. R., Schön, M., Semnani-Azad, Z., Sevilla-Gonzalez, M., Svalastoga, P., Takele, W. W., Tam, C. H. T., Thuesen, Anne Cathrine Baun, Tosur, M., Wallace, A. S., Wang, C. C., Wong, J. J., Yamamoto, J. M., Young, K., Amouyal, C., Lepola, Mette Andersen, Bonham, M. P., Chen, M., Cheng, F., Chikowore, T., Chivers, S. C., Clemmensen, Christoffer, Dabelea, D., Dawed, A. Y., Deutsch, A. J., Dickens, L. T., DiMeglio, L. A., Dudenhöffer-Pfeifer, M., Evans-Molina, C., Fernández-Balsells, M. M., Fitipaldi, H., Fitzpatrick, S. L., Gitelman, S. E., Goodarzi, M. O., Grieger, J. A., Guasch Ferre, Marta, Habibi, N., Hansen, Torben, Huang, C., Harris-Kawano, A., Ismail, H. M., Hoag, B., Johnson, R. K., Jones, A. G., Koivula, R. W., Leong, A., Leung, G. K. W., Libman, I. M., Liu, K., Long, S. A., Lowe, W. L., Morton, R. W., Motala, A. A., Onengut-Gumuscu, S., Pankow, J. S., Pathirana, M., Pazmino, S., Perez, D., Petrie, J. R., Powe, C. E., Quinteros, A., Jain, R., Ray, D., Ried-Larsen, M., Saeed, Z., Santhakumar, V., Kanbour, S., Sarkar, S., Monaco, G. S. F., Scholtens, D. M., Selvin, E., Sheu, W. H. H., Speake, C., Stanislawski, M. A., Steenackers, N., Steck, A. K., Stefan, N., Støy, J., Taylor, R., Tye, S. C., Ukke, G. G., Urazbayeva, M., Van der Schueren, B., Vatier, C., Wentworth, J. M., Hannah, W., White, S. L., Yu, G., Zhang, Y., Zhou, S. J., Beltrand, J., Polak, M., Aukrust, I., de Franco, E., Flanagan, S. E., Maloney, K. A., McGovern, A., Molnes, J., Nakabuye, Mariam, Njølstad, P. R., Pomares-Millan, H., Provenzano, M., Saint-Martin, C., Zhang, C., Zhu, Y., Auh, S., de Souza, R., Fawcett, A. J., Gruber, C., Mekonnen, E. G., Mixter, E., Sherifali, D., Eckel, R. H., Nolan, J. J., Philipson, L. H., Brown, R. J., Billings, L. K., Boyle, K., Costacou, T., Dennis, J. M., Florez, J. C., Gloyn, A. L., Gomez, M. F., Gottlieb, P. A., Greeley, S. A. W., Griffin, K., Hattersley, A. T., Hirsch, I. B., Hivert, M. F., Hood, K. K., Josefson, J. L., Kwak, S. H., Laffel, L. M., Lim, S. S., Loos, Ruth, Ma, R. C. W., Mathieu, C., Mathioudakis, N., Meigs, J. B., Misra, S., Mohan, V., Murphy, R., Oram, R., Owen, K. R., Ozanne, S. E., Pearson, E. R., Perng, W., Pollin, T. I., Pop-Busui, R., Pratley, R. E., Redman, L. M., Redondo, M. J., Reynolds, R. M., Semple, R. K., Sherr, J. L., Sims, E. K., Sweeting, A., Tuomi, T., Udler, M. S., Vesco, K. K., Vilsbøll, Tina, Wagner, R., Rich, S. S. & Franks, P. W., 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease

    Gupta, Y., Friedman, D. J., McNulty, M. T., Khan, A., Lane, B., Wang, C., Ke, J., Jin, G., Wooden, B., Knob, A. L., Lim, T. Y., Appel, G. B., Huggins, K., Liu, L., Mitrotti, A., Stangl, M. C., Bomback, A., Westland, R., Bodria, M., Marasa, M. & 60 others, Shang, N., Cohen, D. J., Crew, R. J., Morello, W., Canetta, P., Radhakrishnan, J., Martino, J., Liu, Q., Chung, W. K., Espinoza, A., Luo, Y., Wei, W., Feng, Q., Weng, C., Fang, Y., Kullo, I. J., Naderian, M., Limdi, N., Irvin, M. R., Tiwari, H., Mohan, S., Rao, M., Dube, G. K., Chaudhary, N. S., Gutiérrez, O. M., Judd, S. E., Cushman, M., Lange, L. A., Lange, E. M., Bivona, D. L., Verbitsky, M., Winkler, C. A., Kopp, J. B., Santoriello, D., Batal, I., Pinheiro, S. V. B., Oliveira, E. A., Simoes e Silva, A. C., Pisani, I., Fiaccadori, E., Lin, F., Gesualdo, L., Amoroso, A., Ghiggeri, G. M., D’Agati, V. D., Magistroni, R., Kenny, E. E., Loos, Ruth, Montini, G., Hildebrandt, F., Paul, D. S., Petrovski, S., Goldstein, D. B., Kretzler, M., Gbadegesin, R., Gharavi, A. G., Kiryluk, K., Sampson, M. G., Pollak, M. R. & Sanna-Cherchi, S., 2023, In: Nature Communications. 14, 8 p., 7836.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations

    Stalbow, L. A., Preuss, M. H., Smit, Roelof Adriaan Johan, Chami, N., Bjørkhaug, L., Aukrust, I., Gloyn, A. L. & Loos, Ruth, 2023, In: Diabetologia. 66, p. 116-126 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. The genetic determinants of recurrent somatic mutations in 43,693 blood genomes

    Weinstock, J. S., Laurie, C. A., Broome, J. G., Taylor, K. D., Guo, X., Shuldiner, A. R., O'Connell, J. R., Lewis, J. P., Boerwinkle, E., Barnes, K. C., Chami, N., Kenny, E. E., Loos, R. J. F., Fornage, M., Redline, S., Cade, B. E., Gilliland, F. D., Chen, Z., Gauderman, W. J., Kumar, R. & 31 others, Grammer, L., Schleimer, R. P., Psaty, B. M., Bis, J. C., Brody, J. A., Silverman, E. K., Yun, J. H., Qiao, D., Weiss, S. T., Lasky-Su, J., DeMeo, D. L., Palmer, N. D., Freedman, B. I., Bowden, D. W., Cho, M. H., Vasan, R. S., Johnson, A. D., Yanek, L. R., Becker, L. C., Kardia, S., He, J., Kaplan, R., Heckbert, S. R., Smith, N. L., Wiggins, K. L., Arnett, D. K., Irvin, M. R., Tiwari, H., Correa, A., Raffield, L. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, In: Science Advances. 9, 17, p. eabm4945

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes

    Huerta-Chagoya, A., Schroeder, P., Mandla, R., Deutsch, A. J., Zhu, W., Petty, L., Yi, X., Cole, J. B., Udler, M. S., Dornbos, P., Porneala, B., DiCorpo, D., Liu, C. T., Li, J. H., Szczerbiński, L., Kaur, V., Kim, J., Lu, Y., Martin, A., Eizirik, D. L. & 31 others, Marchetti, P., Marselli, L., Chen, L., Srinivasan, S., Todd, J., Flannick, J., Gubitosi-Klug, R., Levitsky, L., Shah, R., Kelsey, M., Burke, B., Dabelea, D. M., Divers, J., Marcovina, S., Stalbow, L., Loos, Ruth, Darst, B. F., Kooperberg, C., Raffield, L. M., Haiman, C., Sun, Q., McCormick, J. B., Fisher-Hoch, S. P., Ordoñez, M. L., Meigs, J., Baier, L. J., González-Villalpando, C., González-Villalpando, M. E., Orozco, L., García-García, L. & Mexican Biobank, M. B., 2023, In: Diabetologia. 66, p. 1273-1288 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program

    Armstrong, N. D., Srinivasasainagendra, V., Ammous, F., Assimes, T. L., Beitelshees, A. L., Brody, J., Cade, B. E., Ida Chen, Y-D., Chen, H., de Vries, P. S., Floyd, J. S., Franceschini, N., Guo, X., Hellwege, J. N., House, J. S., Hwu, C-M., Kardia, S. L. R., Lange, E. M., Lange, L. A., McDonough, C. W. & 24 others, Montasser, M. E., O'Connell, J. R., Shuey, M. M., Sun, X., Tanner, R. M., Wang, Z., Zhao, W., Carson, A. P., Edwards, T. L., Kelly, T. N., Kenny, E. E., Kooperberg, C., Loos, Ruth, Morrison, A. C., Motsinger-Reif, A., Psaty, B. M., Rao, D. C., Redline, S., Rich, S. S., Rotter, J. I., Smith, J. A., Smith, A. V., Irvin, M. R. & Arnett, D. K., 2023, In: Frontiers in Genetics. 14, 1278215.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 183694311