Børge Nordestgaard
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Clinical Biochemistry
- Published
ABCA7 and risk of dementia and vascular disease in the Danish population
Kjeldsen, E. W., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: Annals of Clinical and Translational Neurology. 5, 1, p. 41-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation- and Meta-Analyses of 137 895 Individuals
Wulff, A. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 660-668Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
Wu, L., Shi, W., Long, J., Guo, X., Michailidou, K., Beesley, J., Bolla, M. K., Shu, X-O., Lu, Y., Cai, Q., Al-Ejeh, F., Rozali, E., Wang, Q., Dennis, J., Li, B., Zeng, C., Feng, H., Gusev, A., Barfield, R. T., Andrulis, I. L. & 31 others, , 2018, In: Nature Genetics. 50, 7, p. 968-978 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AA9int: SNP interaction pattern search using non-hierarchical additive model set
PRACTICAL consortium, P. C., 2018, In: Bioinformatics. 34, 24, p. 4141-4150 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AHRR hypomethylation, lung function, lung function decline and respiratory symptoms
Kodal, J. B., Kobylecki, C. J., Vedel-Krogh, S., Nordestgaard, Børge & Bojesen, Stig Egil, 2018, In: The European Respiratory Journal. 51, 3, 1701512.Research output: Contribution to journal › Journal article › Research › peer-review
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Absolute 10-year risk of dementia by age, sex and APOE genotype: A population-based cohort study
Rasmussen, K. L., Tybjarg-Hansen, A., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: CMAJ. 190, 35, p. E1033-E1041Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Advances in lipid-lowering therapy through gene-silencing technologies
Nordestgaard, Børge, Nicholls, S. J., Langsted, A., Ray, K. K. & Tybjærg-Hansen, Anne, 2018, In: Nature Reviews Cardiology. 15, p. 261-272Research output: Contribution to journal › Review › Research › peer-review
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Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract
European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 2018, In: European Heart Journal. 39, 27, p. 2526-2539 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Airflow limitation in people living with HIV and matched uninfected controls
Ronit, A., Lundgren, Jens, Afzal, Shoaib, Benfield, Thomas, Roen, A., Mocroft, A., Gerstoft, Jan, Nordestgaard, Børge, Vestbo, J., Nielsen, S. D. & Copenhagen Co-morbidity in HIV infection (COCOMO) study group, C. C. I. H. I. (. S. G., 2018, In: Thorax. 73, 5, p. 431-438Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alcohol Intake and Risk of Ischemic and Haemorrhagic Stroke: Results from a Mendelian Randomisation Study
Christensen, A. I., Nordestgaard, Børge & Tolstrup, J. S., 2018, In: Journal of Stroke. 20, 2, p. 218-227Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An updated Alzheimer hypothesis: Complement C3 and risk of Alzheimer's disease-A cohort study of 95,442 individuals
Rasmussen, K. L., Nordestgaard, Børge, Frikke-Schmidt, Ruth & Nielsen, S. F., 2018, In: Alzheimer's & Dementia. 14, 12, p. 1589-1601 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
Schumacher, F. R., Al Olama, A. A., Berndt, S. I., Sorensen, K. D., Orntoft, T. F., Borre, M., Nordestgaard, Børge, Røder, Andreas, Iversen, P., Australian Prostate Cancer BioResource, A. P. C. B., The IMPACT Study, T. I. S., Canary PASS Investigators, C. P. I., Breast and Prostate Cancer Cohort Consortium (BPC3), B. A. P. C. C. C. (., The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, T. P. (. C. A. G. T. I. C. A. I. T. G. C., Cancer of the Prostate in Sweden (CAPS), C. O. T. P. I. S. (., Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS), P. C. G. A. S. O. U. S. L. (., The Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium, T. G. A. A. M. I. O. (. L. I. I. P. C. S. (. C., Kote-Jarai, Z., Haiman, C. A. & Eeles, R. A., 2018, In: Nature Genetics. 50, p. 928-936Research output: Contribution to journal › Letter › Research › peer-review
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Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis
European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium, E. P. I. I. C. A. N. D. (. C., 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults
Lu, L., Bennett, D. A., Millwood, I. Y., Parish, S., McCarthy, M. I., Mahajan, A., Lin, X., Bragg, F., Guo, Y., Holmes, M. V., Afzal, Shoaib, Nordestgaard, Børge, Bian, Z., Hill, M., Walters, R. G., Li, L., Chen, Z. & Clarke, R., 2018, In: PLoS Medicine. 15, 5, 17 p., e1002566.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood eosinophil count and risk of pneumonia hospitalisations in individuals with COPD
Vedel-Krogh, S., Nordestgaard, Børge, Lange, Peter, Vestbo, J. & Nielsen, S. F., 2018, In: European Respiratory Journal. 51, 5, p. 1-10 10 p., 1800120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular disease risk associated with elevated lipoprotein(a) attenuates at low low-density lipoprotein cholesterol levels in a primary prevention setting
Verbeek, R., Hoogeveen, R. M., Langsted, A., Stiekema, L. C. A., Verweij, S. L., Hovingh, G. K., Wareham, N. J., Khaw, K., Boekholdt, S. M., Nordestgaard, Børge & Stroes, E. S. G., 2018, In: European Heart Journal. 39, 27, p. 2589-2596 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characteristics and outcomes of chronic cough in individuals with asthma: a population-based study
Dahl, Morten, Colak, Y., Afzal, Shoaib, Lange, Peter, Laursen, L. & Nordestgaard, Børge, 2018, In: European Respiratory Journal. 52, Supplement 62, 1 p., PA3908.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chylomicronemia risk factors ranked by importance for the individual and community in 108 711 women and men
Pedersen, S. B., Varbo, A., Langsted, A. & Nordestgaard, Børge, 2018, In: Journal of Internal Medicine. 283, 4, p. 392-404Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel
Convened by the Familial Hypercholesterolemia Foundation, C. B. T. F. H. F., 2018, In: Journal of the American College of Cardiology. 72, 6, p. 662-680 19 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Combined value of exhaled nitric oxide and blood eosinophils in chronic airway disease: the Copenhagen General Population Study
Colak, Y., Afzal, Shoaib, Nordestgaard, Børge, Marott, J. L. & Lange, Peter, 2018, In: European Respiratory Journal. 52, 2, 13 p., 1800616.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of Five Major Guidelines for Statin Use in Primary Prevention in a Contemporary General Population
Mortensen, M. B. & Nordestgaard, Børge, 2018, In: Annals of Internal Medicine. 168, 2, p. 85-92 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complement C3 and Risk of Diabetic Microvascular Disease: A Cohort Study of 95202 Individuals from the General Population
Rasmussen, K. L., Nordestgaard, Børge & Nielsen, S. F., Jul 2018, In: Clinical Chemistry. 64, 7, p. 1113-1124 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computed tomography quantification of emphysema in people living with HIV and uninfected controls
Ronit, A., zwp671, zwp671, Hoseth, V. S., Abou-Kassem, D., Kühl, J. T., Benfield, Thomas, Gerstoft, Jan, Afzal, Shoaib, Nordestgaard, Børge, Lundgren, Jens, Vestbo, J., Kofoed, Klaus Fuglsang, Nielsen, S. D. & Copenhagen Comorbidity in HIV Infection (COCOMO) study group, C. C. I. H. I. (. S. G., 2018, In: The European Respiratory Journal. 52, 1, 9 p., 1800296.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coronary artery calcium assessed with calibrated mass scoring in asymptomatic individuals: results from the Copenhagen General Population Study
Knudsen, A. D., Fuchs, A., Kühl, J. T., Arnold, B. A., Nordestgaard, Børge, Køber, Lars Valeur & Kofoed, Klaus Fuglsang, 2018, In: European Radiology. 28, 11, p. 4607-4614 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostic performance of clinical characteristics to detect airflow limitation in people living with HIV and in uninfected controls
the Copenhagen Co-morbidity in HIV Infection (COCOMO) Study Group, T. C. C. I. H. I. (. S. G., 2018, In: HIV Medicine. 19, 10, p. 751-755 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eradicating the Burden of Atherosclerotic Cardiovascular Disease by Lowering Apolipoprotein B Lipoproteins Earlier in Life
Robinson, J. G., Williams, K. J., Gidding, S., Borén, J., Tabas, I., Fisher, E. A., Packard, C., Pencina, M., Fayad, Z. A., Mani, V., Rye, K. A., Nordestgaard, Børge, Tybjærg‐hansen, A., Douglas, P. S., Nicholls, S. J., Pagidipati, N. & Sniderman, A., 2018, In: Journal of the American Heart Association. 7, 20, p. 1-12 e009778.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial Hypercholesterolemia and Risk of Peripheral Arterial Disease and Chronic Kidney Disease
Emanuelsson, F., Nordestgaard, Børge & Benn, Marianne, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4491-4500Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
Dadaev, T., Saunders, E. J., Newcombe, P. J., Anokian, E., Leongamornlert, D. A., Brook, M. N., Cieza-Borrella, C., Mijuskovic, M., Wakerell, S., Olama, A. A. A., Schumacher, F. R., Berndt, S. I., Benlloch, S., Ahmed, M., Goh, C., Sheng, X., Zhang, Z., Muir, K., Govindasami, K., Lophatananon, A. & 290 others, , 2018, In: Nature Communications. 9, 1, 2256.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From genome-wide association studies to Mendelian randomization: novel opportunities for understanding cardiovascular disease causality, pathogenesis, prevention, and treatment
Benn, Marianne & Nordestgaard, Børge, 15 Jul 2018, In: Cardiovascular Research. 114, 9, p. 1192-1208 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
Gusarova, V., O'Dushlaine, C., Teslovich, T. M., Benotti, P. N., Mirshahi, T., Gottesman, O., Van Hout, C. V., Murray, M. F., Mahajan, A., Nielsen, J. B., Fritsche, L., Wulff, A. B., Gudbjartsson, D. F., Sjögren, M., Emdin, C. A., Scott, R. A., Lee, W. J., Small, A., Kwee, L. C., Dwivedi, O. P. & 61 others, , 2018, In: Nature Communications. 9, 1, 2252.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease
Qayyum, F., Lauridsen, B. K., Frikke-Schmidt, Ruth, Kofoed, Klaus Fuglsang, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 22, p. 2106-2116 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: Cohort studies and meta-analyses of 362,338 individuals
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: BMC Medicine. 16, 11 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetically high plasma vitamin C and urate: a Mendelian randomization study in 106 147 individuals from the general population
Kobylecki, C. J., Afzal, Shoaib & Nordestgaard, Børge, 2018, In: Rheumatology. 57, 10, p. 1769-1776Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
Vijayakrishnan, J., Studd, J., Broderick, P., Kinnersley, B., Holroyd, A., Law, P. J., Kumar, R., Allan, J. M., Harrison, C. J., Moorman, A. V., Vora, A., Roman, E., Rachakonda, S., Kinsey, S. E., Sheridan, E., Thompson, P. D., Irving, J. A., Koehler, R., Hoffmann, P., Nöthen, M. M. & 31 others, , 2018, In: Nature Communications. 9, 1, 14 p., 1340.Research output: Contribution to journal › Journal article › Research › peer-review
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Germline variation at 8q24 and prostate cancer risk in men of European ancestry
Matejcic, M., Saunders, E. J., Dadaev, T., Brook, M. N., Wang, K., Sheng, X., Olama, A. A. A., Schumacher, F. R., Ingles, S. A., Govindasami, K., Benlloch, S., Berndt, S. I., Albanes, D., Koutros, S., Muir, K., Stevens, V. L., Gapstur, S. M., Tangen, C. M., Batra, J., Clements, J. & 31 others, , 2018, In: Nature Communications. 9, 4616.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HIV Status Is a Greater Determinant of Low Self-perceived Life Expectancy Than Cigarette Smoking in a Well-resourced Setting
Ronit, A., Ahlström, M. G., Knudsen, A. D., Gerstoft, Jan, Nordestgaard, Børge, Benfield, Thomas & Nielsen, S. D., 2018, In: J A I D S. 79, 2, p. e81-e84Research output: Contribution to journal › Comment/debate › Research › peer-review
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HIV infection is independently associated with a higher concentration of alpha-1 antitrypsin
Thudium, R., Lundgren, Jens, Benfield, Thomas, Nordestgaard, Børge, Borges, Á., Gerstoft, Jan, Nielsen, S. & Ronit, A., 2018, In: HIV Medicine. 19, 10, p. 745-750Research output: Contribution to journal › Journal article › Research › peer-review
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High plasma 25-hydroxyvitamin D and high risk of nonmelanoma skin cancer: a Mendelian randomization study of 97 849 individuals
Winsløw, U. C., Nordestgaard, Børge & Afzal, Shoaib, 2018, In: British Journal of Dermatology. 178, 6, p. 1388-1395 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Higher Risk of Abdominal Obesity, Elevated Low-Density Lipoprotein Cholesterol, and Hypertriglyceridemia, but not of Hypertension, in People Living With Human Immunodeficiency Virus (HIV): Results From the Copenhagen Comorbidity in HIV Infection Study
Gelpi, M., Afzal, Shoaib, Lundgren, Jens, Ronit, A., Roen, A., Mocroft, A., Gerstoft, Jan, Lebech, Anne-Mette, Lindegaard, Birgitte, Kofoed, Klaus Fuglsang, Nordestgaard, Børge & Nielsen, S. D., 2018, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 67, 4, p. 579-586 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma
Went, M., Sud, A., Försti, A., Halvarsson, B. M., Weinhold, N., Kimber, S., van Duin, M., Thorleifsson, G., Holroyd, A., Johnson, D. C., Li, N., Orlando, G., Law, P. J., Ali, M., Chen, B., Mitchell, J. S., Gudbjartsson, D. F., Kuiper, R., Stephens, O. W., Bertsch, U. & 31 others, , 13 Sep 2018, In: Nature Communications. 9, 10 p., 3707.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Plasma Ferritin Concentration and Low-Grade Inflammation-A Mendelian Randomization Study
Moen, I. W., Bergholdt, H. K. M., Mandrup-Poulsen, Thomas, Nordestgaard, Børge & Ellervik, Christina, 2018, In: Clinical Chemistry. 64, 2, p. 374-385 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is It Time for New Thinking About High-Density Lipoprotein?
Madsen, C. M. & Nordestgaard, Børge, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 484-486 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Is smoking heaviness causally associated with alcohol use? A Mendelian randomization study in four European cohorts
Taylor, M., Rode, L., Bjørngaard, J., Taylor, A. E., Bojesen, Stig Egil, Åsvold, B. O., Gabrielsen, M. E., Lewis, G., Nordestgaard, Børge, Romundstad, P. R., Hickman, M. & Munafò, M. R., 2018, In: International Journal of Epidemiology. 47, 4, p. 1098-1105Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kardiológia v roku 2017
Nordestgaard, Børge, Cosentino, F., Landmesser, U. & Laufs, U., 2018, In: Cardiology Letters. 27, 3, p. 124-142Research output: Contribution to journal › Review › Research › peer-review
- Published
Lactase persistence, milk intake, and mortality in the Danish general population: a Mendelian randomization study
Bergholdt, H. K. M., Nordestgaard, Børge, Varbo, A. & Ellervik, Christina, 1 Feb 2018, In: European Journal of Epidemiology. 33, 2, p. 171–181Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactase persistence, milk intake, hip fracture and bone mineral density: a study of 97 811 Danish individuals and a meta-analysis
Bergholdt, H. K. M., Larsen, M. K., Varbo, A., Nordestgaard, Børge & Ellervik, Christina, 2018, In: Journal of Internal Medicine. 284, 3, p. 254-269 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
Mancuso, N., Gayther, S., Gusev, A., Zheng, W., Penney, K. L., Kote-Jarai, Z., Eeles, R., Freedman, M., Haiman, C., Pasaniuc, B., Henderson, B. E., Benlloch, S., Schumacher, F. R., Olama, A. A. A., Muir, K., Berndt, S. I., Conti, D. V., Wiklund, F., Chanock, S., Stevens, V. L. & 31 others, , 2018, In: Nature Communications. 9, 1, 11 p., 4079.Research output: Contribution to journal › Journal article › Research › peer-review
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Liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease: Mendelian randomization and meta-analysis of 279 013 individuals
Lauridsen, B. K., Stender, Steen, zwp671, zwp671, Kofoed, Klaus Fuglsang, Køber, Lars Valeur, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 5, p. 385-393 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low concentrations of 25-hydroxyvitamin d and long-term prognosis of copd: A prospective cohort study
Færk, Gitte, Çolak, Y., Afzal, Shoaib & Nordestgaard, Børge, 2018, In: European Journal of Epidemiology. 33, 6, p. 567-577 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lymphopenia and risk of infection and infection-related death in 98,344 individuals from a prospective Danish population-based study
Warny, M., Helby, J., Nordestgaard, Børge, Birgens, H. & Bojesen, Stig Egil, 2018, In: PLoS Medicine. 15, 11, 22 p., e1002685.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11241
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RAD51B in Familial Breast Cancer
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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci
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Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study
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