Kenn Holmbeck
Associate Professor
Virology
Nørre Allé 14
2200 København N
- Published
A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo
Motley, M. P., Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Spencer, D. E., Szabo, R., Holmbeck, Kenn, Flick, M. J., Lawrence, D. A., Castellino, F. J., Weigert, R. & Bugge, T. H., 2016, In: Blood. 127, 9, p. 1085-1096 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A regulatory cascade involving retinoic acid, Cbfa1, and matrix metalloproteinases is coupled to the development of a process of perichondrial invasion and osteogenic differentiation during bone formation
Jiménez, M. J., Balbín, M., Alvarez, J., Komori, T., Bianco, P., Holmbeck, Kenn, Birkedal-Hansen, H., López, J. M. & López-Otín, C., 24 Dec 2001, In: The Journal of Cell Biology. 155, 7, p. 1333-44 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature
Lehti, K., Allen, E., Birkedal-Hansen, H., Holmbeck, Kenn, Miyake, Y., Chun, T. & Weiss, S. J., 15 Apr 2005, In: Genes & Development. 19, 8, p. 979-91 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals
Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Feng, S., Marichal-Gallardo, P., Holmbeck, Kenn, Pihl, A. F., Fernandez-Antunez, C., Alzua, G. P., Hartmann, Katrine Top, Pham, Long, Zhou, Y., Gammeltoft, Karen Anbro, Fahnøe, Ulrik, Schneider, Uffe Vest, Pedersen, Gabriel Kristian, Jensen, Henrik Elvang, Christensen, Jan Pravsgaard, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: iScience. 26, 2, 105949.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aspects of extracellular matrix remodeling in development and disease
Holmbeck, Kenn & Szabova, L., Mar 2006, In: Birth Defects Research. Part C: Embryo Today Reviews (Print). 78, 1, p. 11-23 13 p.Research output: Contribution to journal › Review › Research
Biglycan modulates angiogenesis and bone formation during fracture healing
Berendsen, A. D., Pinnow, E. L., Maeda, A., Brown, A. C., McCartney-Francis, N., Kram, V., Owens, R. T., Robey, P. G., Holmbeck, Kenn, de Castro, L. F., Kilts, T. M. & Young, M. F., Apr 2014, In: Matrix Biology. 35, p. 223-31 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Btbd7 is essential for region-specific epithelial cell dynamics and branching morphogenesis in vivo
Daley, W. P., Matsumoto, K., Doyle, A. D., Wang, S., DuChez, B. J., Holmbeck, Kenn & Yamada, K. M., 2017, In: Development (Cambridge). 144, 12, p. 2200-2211 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion
Makareeva, E., Han, S., Vera, J. C., Sackett, D. L., Holmbeck, Kenn, Phillips, C. L., Visse, R., Nagase, H. & Leikin, S., 1 Jun 2010, In: Cancer Research. 70, 11, p. 4366-74 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Collagen dissolution by keratinocytes requires cell surface plasminogen activation and matrix metalloproteinase activity
Netzel-Arnett, S., Mitola, D. J., Yamada, S. S., Chrysovergis, K., Holmbeck, Kenn, Birkedal-Hansen, H. & Bugge, T. H., 22 Nov 2002, In: The Journal of Biological Chemistry. 277, 47, p. 45154-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Collagenase in cranial morphogenesis
Holmbeck, Kenn, 2005, In: Cells, Tissues, Organs. 181, 3-4, p. 154-65 12 p.Research output: Contribution to journal › Review › Research
- Published
Complementary roles of intracellular and pericellular collagen degradation pathways in vivo
Wagenaar-Miller, R. A., Engelholm, Lars Henning, Gavard, J., Yamada, S. S., Gutkind, J. S., Behrendt, Niels, Bugge, T. H. & Holmbeck, Kenn, Sep 2007, In: Molecular and Cellular Biology. 27, 18, p. 6309-22 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Constitutive expression of Gsα(R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history
Saggio, I., Remoli, C., Spica, E., Cersosimo, S., Sacchetti, B., Robey, P. G., Holmbeck, Kenn, Cumano, A., Boyde, A., Bianco, P. & Riminucci, M., 2014, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 29, 11, p. 2357-68 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream
Langenfurth, A., Gu, S., Bautze, V., Zhang, C., Neumann, J. E., Schüller, U., Stock, K., Wolf, S. A., Maier, A., Mastrella, G., Pak, A., Cheng, H., Kälin, R. E., Holmbeck, Kenn, Strotmann, J., Kettenmann, H. & Glass, R., 30 Aug 2016, In: Scientific Reports. 6, 32203.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of craniofacial structures in transgenic mice with constitutively active PTH/PTHrP receptor
Tsutsui, T. W., Riminucci, M., Holmbeck, Kenn, Bianco, P. & Robey, P. G., Feb 2008, In: Bone. 42, 2, p. 321-31 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells
Ingvarsen, S. Z., Madsen, D. H., Hillig, T., Lund, L. R., Holmbeck, Kenn, Behrendt, Niels & Engelholm, L. H., 2008, In: Biological Chemistry. 389, 7, p. 943-953 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals
Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Holmbeck, K., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P. & 5 others, , 6 Jul 2022.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland
Szabova, L., Yamada, S. S., Birkedal-Hansen, H. & Holmbeck, Kenn, Oct 2005, In: Journal of Cellular Physiology. 205, 1, p. 123-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation
Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, Henrik, Høyer-Hansen, G., Holmbeck, Kenn, Bugge, T. H. & Behrendt, Niels, 14 Sep 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo
Zhang, W., Matrisian, L. M., Holmbeck, Kenn, Vick, C. C. & Rosenthal, E. L., 6 Mar 2006, In: BMC Cancer. 6, p. 52Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Full-length sequence analysis of hepatitis C virus genotype 3b strains and development of an in vivo infectious 3b cDNA clone
Bajpai, P. S., Collignon, Laura Maria F, Sølund, C., Madsen, L. W., Christensen, P. B., Øvrehus, A., Weis, Nina, Holmbeck, Kenn, Fahnøe, Ulrik & Bukh, Jens, 2023, In: Journal of Virology. 97, 12, 23 p., 00925.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GNAS transcripts in skeletal progenitors: evidence for random asymmetric allelic expression of Gs alpha
Michienzi, S., Cherman, N., Holmbeck, Kenn, Funari, A., Collins, M. T., Bianco, P., Robey, P. G. & Riminucci, M., 15 Aug 2007, In: Human Molecular Genetics. 16, 16, p. 1921-30 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gelatinase A (MMP-2) activation by skin fibroblasts: dependence on MT1-MMP expression and fibrillar collagen form
Ruangpanit, N., Chan, D., Holmbeck, Kenn, Birkedal-Hansen, H., Polarek, J., Yang, C., Bateman, J. F. & Thompson, E. W., Jun 2001, In: Matrix Biology. 20, 3, p. 193-203 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
Markovic, D. S., Vinnakota, K., Chirasani, S., Synowitz, M., Raguet, H., Stock, K., Sliwa, M., Lehmann, S., Kälin, R., van Rooijen, N., Holmbeck, Kenn, Heppner, F. L., Kiwit, J., Matyash, V., Lehnardt, S., Kaminska, B., Glass, R. & Kettenmann, H., 28 Jul 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 30, p. 12530-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide
Sherwood, A. V., Rivera-Rangel, L. R., Ryberg, L. A., Larsen, H. S., Anker, K. M., Costa, R., Vågbø, C. B., Jakljevič, E., Pham, L. V., Fernandez-Antunez, C., Indrisiunaite, G., Podolska-Charlery, A., Grothen, J. E. R., Langvad, N. W., Fossat, N., Offersgaard, A., Al-Chaer, A., Nielsen, L., Kuśnierczyk, A., Sølund, C. & 8 others, , 2023, In: Nature. 619, p. 811-818Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of molar eruption and root elongation in MT1-MMP-deficient mice
Beertsen, W., Holmbeck, Kenn, Niehof, A., Bianco, P., Chrysovergis, K., Birkedal-Hansen, H. & Everts, V., 2003, In: Connective Tissue Research. 44 Suppl 1, p. 298-9 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 164419721
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An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals
Research output: Contribution to journal › Journal article › Research › peer-review
Published