Bo Torben Porse

Bo Torben Porse

Professor, Clinical Professor

Member of:

  • Internal Medicine: Haematology

ORCID: 0000-0001-6043-0844

Publication year:
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76 - 100 out of 125Page size: 25
  1. 2015
  2. Published

    Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

    Rasmussen, K. D., Jia, G., Johansen, Jens Vilstrup, Pedersen, M. T., Rapin, N., Bagger, F. O., Porse, Bo Torben, Bernard, O. A., Christensen, J. & Helin, K., 17 Apr 2015, In: Genes & Development. p. 910-922 13 p., 29.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Disease evolution and outcomes in familial AML with germline CEBPA mutations

    Tawana, K., Wang, J., Renneville, A., Bödör, C., Hills, R., Loveday, C., Savic, A., Van Delft, F. W., Treleaven, J., Georgiades, P., Uglow, E., Asou, N., Uike, N., Debeljak, M., Jazbec, J., Ancliff, P., Gale, R., Thomas, X., Mialou, V., Döhner, K. & 21 others, Bullinger, L., Mueller, B., Pabst, T., Stelljes, M., Schlegelberger, B., Wozniak, E., Iqbal, S., Okosun, J., Araf, S., Frank, Anne-Katrine, Lauridsen, F. B., Porse, Bo Torben, Nerlov, C., Owen, C., Dokal, I., Gribben, J., Smith, M., Preudhomme, C., Chelala, C., Cavenagh, J. & Fitzgibbon, J., 3 Sep 2015, In: Blood. 126, 10, p. 1214-23 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

    Paul, F., Arkin, Y., Giladi, A., Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Winter, D., Lara-Astiaso, D., Gury, M., Weiner, A., David, E., Cohen, N., Lauridsen, F. K. B., Haas, S., Schlitzer, A., Mildner, A., Ginhoux, F., Jung, S., Trumpp, A., Porse, B. T. & 2 others, Tanay, A. & Amit, I., 17 Dec 2015, In: Cell. 163, 7, p. 1663-77 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2016
  6. Published

    Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality

    Pundhir, Sachin, Bagger, F. O., Lauridsen, F. K. B., Rapin, N. P. J. & Porse, Bo Torben, 2016, In: Nucleic Acids Research. 44, 9, p. 4037-4051 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    UPF2-dependent nonsense-mediated mRNA decay pathway is essential for spermatogenesis by selectively eliminating longer 3'UTR transcripts

    Bao, J., Vitting-Seerup, K., Waage, J. E., Tang, C., Ge, Y., Porse, Bo Torben & Yan, W., 2016, In: P L o S Genetics. 12, 5, 24 p., e1005863.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis

    Bagger, F. O., Sasivarevic, D., Hadi Sohi, S., Laursen, L. G., Pundhir, Sachin, Sønderby, C. K., Winther, Ole, Rapin, N. & Porse, Bo Torben, 4 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D917-24 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4

    Di Stefano, B., Collombet, S., Jakobsen, J. S., Wierer, M., Sardina, J. L., Lackner, A., Stadhouders, R., Segura-Morales, C., Francesconi, M., Limone, F., Mann, Matthias, Porse, Bo Torben, Thieffry, D. & Graf, T., Apr 2016, In: Nature Cell Biology. 18, 4, p. 371-81 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The multifaceted functions of C/EBPα in normal and malignant haematopoiesis

    Ohlsson, E., Schuster, Mikkel Bruhn, Hasemann, M. & Porse, Bo Torben, Apr 2016, In: Leukemia. 30, 4, p. 767-75 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia

    O'Connor, C., Lohan, F., Campos, J., Ohlsson, E., Salomè, M., Forde, C., Artschwager, R., Liskamp, R. M., Cahill, M. R., Kiely, P. A., Porse, Bo Torben & Keeshan, K., 6 Oct 2016, In: Oncogene. 35, 40, p. 5272-5281 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

    Stunnenberg, H. G., Hirst, M., International Human Epigenome Consortium, I. H. E. C., Helin, K. & Porse, Bo Torben, 17 Nov 2016, In: Cell. 167, 5, p. 1145-1149 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2017
  14. Published

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

    Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, Jens Vilstrup, Rapin, N. P. J., Porse, Bo Torben, Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2018
  16. Published

    A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

    Lauridsen, F. K., Jensen, T. L., Rapin, N., Aslan, D., Wilhelmson, Anna, Pundhir, Sachin, Rehn, M., Paul, F., Giladi, A., Hasemann, M. S., Serup, Palle, Amit, I. & Porse, Bo Torben, 2018, In: Cell Reports. 24, 3, p. 766-780 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors

    Pundhir, Sachin, Bratt Lauridsen, F. K., Schuster, Mikkel Bruhn, Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N. P. J., Waage, J., Hasemann, M. S. & Porse, Bo Torben, 2018, In: Cell Reports. 23, 9, p. 2744-2757 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

    Reckzeh, K., Kizilkaya, Hüsün Sheyma, Helbo, A. S., Estruch Alrich, Montserrat, Deslauriers, A. G., Grover, A., Rapin, N., Asmar, F., Grønbæk, Kirsten, Porse, Bo Torben, Borregaard, N., Vestweber, D., Nerlov, C. & Theilgaard-Mønch, Kim, 2018, In: Blood advances. 2, 13, p. 1628-1632 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates

    Gu, X., Ebrahem, Q., Mahfouz, R. Z., Hasipek, M., Enane, F., Radivoyevitch, T., Rapin, N., Przychodzen, B., Hu, Z., Balusu, R., Cotta, C. V., Wald, D., Argueta, C., Landesman, Y., Martelli, M. P., Falini, B., Carraway, H., Porse, B. T., Maciejewski, J., Jha, B. K. & 1 others, Saunthararajah, Y., 2018, In: The Journal of Clinical Investigation. 128, 10, p. 4260-4279 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    SinaPlot: an enhanced chart for simple and truthful representation of single observations over multiple classes

    Sidiropoulos, N., Sohi, S. H., Pedersen, T. L., Porse, Bo Torben, Winther, Ole, Rapin, N. & Bagger, F. O., 2018, In: Journal of Computational and Graphical Statistics. 27, 3, p. 673-676 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Testosterone is an endogenous regulator of BAFF and splenic B cell number

    Wilhelmson, A. S., Lantero Rodriguez, M., Stubelius, A., Fogelstrand, P., Johansson, I., Buechler, M. B., Lianoglou, S., Kapoor, V. N., Johansson, M. E., Fagman, J. B., Duhlin, A., Tripathi, P., Camponeschi, A., Porse, B. T., Rolink, A. G., Nissbrandt, H., Turley, S. J., Carlsten, H., Mårtensson, I-L., Karlsson, M. C. I. & 1 others, Tivesten, Å., 2018, In: Nature Communications. 9, p. 1-13 13 p., 2067.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2019
  24. Published

    A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

    Morgan, M., Kabayama, Y., Much, C., Ivanova, I., Di Giacomo, M., Auchynnikava, T., Monahan, J. M., Vitsios, D. M., Vasiliauskaitė, L., Comazzetto, S., Rappsilber, J., Allshire, R. C., Porse, Bo Torben, Enright, A. J. & O'Carroll, D., 2019, In: Cell Research. p. 221–232

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Heterozygous loss of Srp72 in mice is not associated with major hematological phenotypes

    D'Altri, T., Schuster, Mikkel Bruhn, Wenzel, Anne & Porse, Bo Torben, 2019, In: European Journal of Haematology. 103, 4, p. 319-328 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response

    Johnson, J. L., Stoica, L., Liu, Y., Zhu, P. J., Bhattacharya, A., Buffington, S., Huq, R., Eissa, N. T., Larsson, O., Porse, B. T., Domingo, D., Nawaz, U., Carroll, R., Jolly, L., Scerri, T. S., Kim, H-G., Brignell, A., Coleman, M. J., Braden, R., Kini, U. & 11 others, Jackson, V., Baxter, A., Bahlo, M., Scheffer, I. E., Amor, D. J., Hildebrand, M. S., Bonnen, P. E., Beeton, C., Gecz, J., Morgan, A. T. & Costa-Mattioli, M., 2019, In: Neuron. 104, 4, p. 665-679 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML

    Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

    Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination

    Søndergaard, E., Rauch, A., Michaut, Magali, Rapin, N., Rehn, M., Wilhelmson, Anna, Camponeschi, A., Hasemann, M. S., Bagger, F. O., Jendholm, J., Knudsen, K. J., Mandrup, S., Mårtensson, I. L. & Porse, Bo Torben, 26 Nov 2019, In: Cell Reports. 29, 9, p. 2756-2769.e6 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2020
  31. Published

    CCAAT enhancer binding protein alpha (CEBPA) biallelic acute myeloid leukaemia: cooperating lesions, molecular mechanisms and clinical relevance

    Wilhelmson, Anna & Porse, Bo Torben, 2020, In: British Journal of Haematology. 190, 4, p. 495-507

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4985646