Niels Behrendt

Niels Behrendt

Clinical Professor

Member of:

  • Clinical Oncology


  1. 2003
  2. Published

    The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation

    Behrendt, Niels, List, K., Andreasen, P. A. & Danø, K., 15 Apr 2003, In: Biochemical Journal. 371, Pt 2, p. 277-87 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2004
  4. Published

    The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodeling

    Behrendt, Niels, Feb 2004, In: Biological Chemistry. 385, 2, p. 103-36 34 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV

    Kjøller, L., Engelholm, Lars Henning, Høyer-Hansen, M., Danø, K., Bugge, T. H. & Behrendt, Niels, 1 Feb 2004, In: Experimental Cell Research. 293, 1, p. 106-16 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma

    Udby, L., Sørensen, O. E., Pass, J., Johnsen, A. H., Behrendt, Niels, Borregaard, N. & Kjeldsen, L., 12 Oct 2004, In: Biochemistry. 43, 40, p. 12877-86 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2005
  8. Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy

    Curino, A. C., Engelholm, Lars Henning, Yamada, S. S., Holmbeck, K., Lund, L. R., Molinolo, A. A., Behrendt, Niels, Nielsen, B. S. & Bugge, T. H., 2005, In: Journal of Cell Biology. 169, 6, p. 977-985 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2007
  10. Published

    Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer

    Sulek, J., Wagenaar-Miller, R. A., Shireman, J., Molinolo, A., Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Behrendt, Niels & Bugge, T. H., Apr 2007, In: Journal of Histochemistry and Cytochemistry. 55, 4, p. 347-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Complementary roles of intracellular and pericellular collagen degradation pathways in vivo

    Wagenaar-Miller, R. A., Engelholm, Lars Henning, Gavard, J., Yamada, S. S., Gutkind, J. S., Behrendt, Niels, Bugge, T. H. & Holmbeck, Kenn, Sep 2007, In: Molecular and Cellular Biology. 27, 18, p. 6309-22 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

    Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, Henrik, Høyer-Hansen, G., Holmbeck, Kenn, Bugge, T. H. & Behrendt, Niels, 14 Sep 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2008
  14. Published

    Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

    Ingvarsen, S. Z., Madsen, D. H., Hillig, T., Lund, L. R., Holmbeck, Kenn, Behrendt, Niels & Engelholm, L. H., 2008, In: Biological Chemistry. 389, 7, p. 943-953 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

    Hillig, T., Engelholm, Lars Henning, Ingvarsen, S., Madsen, Daniel Hargbøl, Gårdsvoll, Henrik, Larsen, J. K., Ploug, Michael, Danø, K., Kjøller, L. & Behrendt, Niels, 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Antibody-mediated Targeting of the Urokinase-type Plasminogen Activator Proteolytic Function Neutralizes Fibrinolysis in Vivo

    Lund, I. K., Jögi, A., Rono, B., Rasch, M. G., Lund, L. R., Almholt, K., Gardsvoll, H., Behrendt, Niels, Romer, J. & Hoyer-Hansen, G., 21 Nov 2008, In: Journal of Biological Chemistry. 283, 47, p. 32506-32515

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2009
  18. Published

    MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny

    Szabova, L., Yamada, S. S., Wimer, H., Chrysovergis, K., Ingvarsen, S., Behrendt, Niels, Engelholm, L. H. & Holmbeck, K., 2009, In: Journal of Bone and Mineral Research. 24, 11, p. 1905-1916 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The collagen receptor uPARAP/Endo180

    Engelholm, Lars Henning, Ingvarsen, S., Jürgensen, Henrik Jessen, Hillig, T., Madsen, Daniel Hargbøl, Nielsen, B. S. & Behrendt, Niels, 1 Jan 2009, In: Frontiers in Bioscience. 14, p. 2103-14 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. 2011
  21. Published

    A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uPARAP/ENDO 180

    Jürgensen, Henrik Jessen, Madsen, Daniel Hargbøl, Ingvarsen, S., Melander, M. C., Gårdsvoll, Henrik, Patthy, L., Engelholm, Lars Henning & Behrendt, Niels, 2011, In: Journal of Biological Chemistry. 286, 37, p. 32736-48 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The non-phagocytic route of collagen uptake: a distinct degradation pathway

    Madsen, Daniel Hargbøl, Ingvarsen, S., Jürgensen, Henrik Jessen, Melander, M. C., Kjøller, L., Moyer, A., Honoré, C., Madsen, M. C., Garred, Peter, Burgdorf, S., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 29 Jul 2011, In: The Journal of Biological Chemistry. 286, 30, p. 26996-7010 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction

    Gårdsvoll, Henrik, Jacobsen, B., Kriegbaum, M. C., Behrendt, Niels, Engelholm, Lars Henning, Østergaard, S. & Ploug, Michael, 23 Sep 2011, In: The Journal of Biological Chemistry. 286, 38, p. 33544-56 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2012
  25. Published

    Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis

    Madsen, D. H., Jürgensen, H. J., Ingvarsen, S. Z., Melander, M. C., Vainer, B., Egerod, Kristoffer Lihme, Hald, A., Rønø, B., Madsen, C. A., Bugge, T. H., Engelholm, L. H. & Behrendt, Niels, 2012, In: Journal of Pathology. 227, 1, p. 94-105 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo

    Lund, I. K., Rasch, M. G., Ingvarsen, S., Pass, J., Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Behrendt, Niels & Høyer-Hansen, G., 2012, In: Frontiers in Pharmacology. 3, p. 122

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment

    Noël, A., Gutiérrez-Fernández, A., Sounni, N. E., Behrendt, Niels, Maquoi, E., Lund, I. K., Cal, S., Hoyer-Hansen, G. & López-Otín, C., 2012, In: Frontiers in Pharmacology. 3, p. 140

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Matrix Proteases in Health and Disease

    Behrendt, Niels, 24 Aug 2012, Wiley-VCH.

    Research output: Book/ReportBookResearchpeer-review

  29. Published

    Preface: Matrix Proteases in Health and Disease

    Behrendt, Niels, 24 Aug 2012, Matrix Proteases in Health and Disease. Wiley-VCH, p. xiii

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptResearchpeer-review

  30. 2013
  31. Published

    Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

    Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Ingvarsen, S., Melander, M. C., Albrechtsen, Reidar, Hald, A., Holmbeck, K., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 2013, In: PloS one. 8, 8, p. e71261

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis

    Ingvarsen, S., Porse, A., Erpicum, C., Maertens, L., Jürgensen, H. J., Madsen, Daniel Hargbøl, Melander, M. C., Gårdsvoll, Henrik, Høyer-Hansen, G., Noel, A., Holmbeck, K., Engelholm, Lars Henning & Behrendt, Niels, 12 Apr 2013, In: Journal of Biological Chemistry. 288, 15, p. 10195-204 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Ficolin-1-PTX3 complex formation promotes clearance of altered self-cells and modulates IL-8 production

    Ma, Y. J., Doni, A., Romani, L., Jürgensen, Henrik Jessen, Behrendt, Niels, Mantovani, A. & Garred, Peter, 1 Aug 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 3, p. 1324-33 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

    Madsen, Daniel Hargbøl, Leonard, D., Masedunskas, A., Moyer, A., Jürgensen, Henrik Jessen, Peters, D. E., Amornphimoltham, P., Selvaraj, A., Yamada, S. S., Brenner, D. A., Burgdorf, S., Engelholm, Lars Henning, Behrendt, Niels, Holmbeck, K., Weigert, R. & Bugge, T. H., 16 Sep 2013, In: Journal of Cell Biology. 202, 6, p. 951-66 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 33867134