Kei Sakamoto
Professor
Sakamoto Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
Member of:
- 2021
- Published
Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965
Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle
Markby, G. R. & Sakamoto, Kei, 1 Jan 2021, Autophagy in Health and Disease. Elsevier, p. 213-225 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2022
- Published
Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis
Neopane, K., Kozlov, N., Negoita, F., Murray-Segal, L., Brink, R., Hoque, A., Ovens, A. J., Tjin, G., McAloon, L. M., Yu, D., Ling, N. X. Y., Sanders, M. J., Oakhill, J. S., Scott, J. W., Steinberg, G. R., Loh, K., Kemp, B. E., Sakamoto, Kei & Galic, S., 2022, In: Cell Reports. 41, 12, 26 p., 111862.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function
Cheung, R., Pizza, G., Chabosseau, P., Rolando, D., Tomas, A., Burgoyne, T., Wu, Z., Salowka, A., Thapa, A., Macklin, A., Cao, Y., Nguyen-Tu, M. S., Dickerson, M. T., Jacobson, D. A., Marchetti, P., Shapiro, J., Piemonti, L., de Koning, E., Leclerc, I., Bouzakri, K. & 4 others, , 2022, In: Diabetes. 71, 7, p. 1525-1545 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism of glycogen synthase inactivation and interaction with glycogenin
Marr, L., Biswas, Dipsikha, Daly, L. A., Browning, C., Vial, S. C. M., Maskell, D. P., Hudson, C., Bertrand, J. A., Pollard, J., Ranson, N. A., Khatter, H., Eyers, C. E., Sakamoto, Kei & Zeqiraj, E., 2022, In: Nature Communications. 13, 1, 14 p., 3372.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site
Sanders, M. J., Ratinaud, Y., Neopane, K., Bonhoure, N., Day, E. A., Ciclet, O., Lassueur, S., Pinta, M. N., Deak, M., Brinon, B., Christen, S., Steinberg, G. R., Barron, D. & Sakamoto, Kei, 2022, In: Journal of Biological Chemistry. 298, 5, 15 p., 101852.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase
Nguyen-Tu, M., Harris, J., Martinez-Sanchez, A., Chabosseau, P., Hu, M., Georgiadou, E., Pollard, A., Otero, P., Lopez-Noriega, L., Leclerc, I., Sakamoto, Kei, Schmoll, D., Smith, D. M., Carling, D. & Rutter, G. A., 2022, In: Diabetologia. 65, p. 997-1011 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PEN2: Metformin’s new partner at lysosome
Sakamoto, Kei & Jessen, N., 2022, In: Cell Research. 32, p. 507-508Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids
Desjardins, E. M., Smith, B. K., Day, E. A., Ducommun, S., Sanders, M. J., Nederveen, J. P., Ford, R. J., Pinkosky, S. L., Townsend, L. K., Gutgesell, R. M., Lu, R., Sakamoto, Kei & Steinberg, G. R., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 48, 8 p., e2119824119.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion
Kneppers, A., Ben Larbi, S., Theret, M., Saugues, A., Dabadie, C., Gsaier, L., Ferry, A., Rhein, P., Gondin, J., Sakamoto, Kei & Mounier, R., 2023, In: iScience. 26, 12, 17 p., 108343.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 227976158
Most downloads
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196
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Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
177
downloads
Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
98
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Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle
Research output: Contribution to journal › Journal article › Research › peer-review
Published