Jens Bukh

Jens Bukh

Professor

Member of:


    1. 2006
    2. Published

      A comprehensive system for consistent numbering of HCV sequences, proteins and epitopes.

      Kuiken, C., Combet, C., Bukh, Jens, Shin-I, T., Deleage, G., Mizokami, M., Richardson, R., Sablon, E., Yusim, K., Pawlotsky, J., Simmonds, P. & Los Alamos HIV Database Group, L. A. H. D. G., 2006, In: Hepatology. 44, 5, p. 1355-61 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      A milestone for hepatitis C virus research: a virus generated in cell culture is fully viable in vivo.

      Bukh, Jens & Purcell, R. H., 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 10, p. 3500-1 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Functional analyses of GB virus B p13 protein: Development of a recombinant GB virus B hepatitis virus with a p7 protein

      Takikawa, S., Engle, R. E., Emerson, S. U., Purcell, R. H., St Claire, M. & Bukh, Jens, 2006, In: Proceedings of the National Academy of Science of the United States of America. 103, 9, p. 3345-50 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Hepatitis C hos hiv-inficerede patienter

      Bukh, Jens & Nielsen, J. O., 2006, In: Ugeskrift for læger. 168, 42, p. 3599-

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. 2007
    7. Published

      Current status of a hepatitis C vaccine: encouraging results but significant challenges ahead

      Mikkelsen, M. & Bukh, Jens, 2007, In: Current Infectious Disease Reports. 9, 2, p. 94-101 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Hepatitis C virus host cell interactions uncovered

      Gottwein, J. & Bukh, Jens, 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 33, p. 13215-6

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells

      Sakai, A., Takikawa, S., Thimme, R., Meunier, J. C., Spangenberg, H. C., Govindarajan, S., Farci, P., Emerson, S. U., Chisari, F. V., Purcell, R. H. & Bukh, Jens, 2007, In: Journal of Virology. 81, 13, p. 7208-7219 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Monitoring of hepatitis C virus quasispecies in chronic infection by matrix-assisted laser desorption ionization-time of flight mass spectrometry mutation detection

      Yea, C., Bukh, Jens, Ayers, M., Roberts, E., Krajden, M. & Tellier, R., 2007, In: Journal of Clinical Microbiology. 45, 3, p. 1053-1057 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses

      Gottwein, J. M., Scheel, Troels Kasper Høyer, Hoegh, A. M., Lademann, J. B., Eugen-Olsen, J., Lisby, G. & Bukh, Jens, 2007, In: Gastroenterology. 133, 5, p. 1614-26 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. 2008
    13. Published

      Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems.

      Gottwein, Judith Margarete & Bukh, Jens, 2008, In: Advances in Virus Research. 71, p. 51-133 82 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization

      Scheel, Troels Kasper Høyer, Gottwein, Judith Margarete, Jensen, T. B., Prentø, Jannick, Høegh, A. M., Alter, H. J., Eugen-Olsen, J. & Bukh, Jens, 2008, In: Proceedings of the National Academy of Science of the United States of America. 105, 3, p. 997-1002 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Development of a TaqMan assay for the six major genotypes of hepatitis C virus: Comparison with commercial assays

      Engle, R. E., Russell, R. S., Purcell, R. H. & Bukh, Jens, 2008, In: Journal of Medical Virology. 80, 1, p. 72-9 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Hepatitis C: the virus and studies of its lifecycle in cell culture systems

      Bukh, Jens, Gottwein, J. M., Scheel, T. K. & Forns, X., 2008, 100 Key Questions on Hepatitis C. Forns, X. (ed.). 1 ed. Barcelona, Spain: Permanyer Publications, Vol. 1. p. 1-15 14 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    17. Published

      Highly Efficient JFH1-Based Cell-Culture System for Hepatitis C Virus Genotype 5a: Failure of Homologous Neutralizing-Antibody Treatment to Control Infection

      Jensen, T. B., Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Høgh, A. M., Eugen-Olsen, J. & Bukh, Jens, 2008, In: Journal of Infectious Diseases. 198, 12, p. 1756-1765 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Immunity against the GBV-B hepatitis virus in tamarins can prevent productive infection following rechallenge and is long-lived

      Bukh, Jens, Engle, R. E., Govindarajan, S. & Purcell, R. H., 2008, In: Journal of Medical Virology. 80, 1, p. 87-94 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death.

      Mateu, G., Donis, R. O., Wakita, T., Bukh, Jens & Grakoui, A., 2008, In: Virology. 376, 2, p. 397-407 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Isolation and characterization of broadly neutralizing human monoclonal antibodies to the e1 glycoprotein of hepatitis C virus

      Meunier, J., Russell, R. S., Goossens, V., Priem, S., Walther, H., Depla, E., Union, A., Faulk, K. N., Bukh, Jens, Emerson, S. U. & Purcell, R. E., 2008, In: Journal of Virology. 82, 2, p. 966-73 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain.

      Vanwolleghem, T., Bukh, Jens, Meuleman, P., Desombere, I., Meunier, J., Alter, H., Purcell, R. H. & Leroux-Roels, G., 2008, In: Hepatology. 47, 6, p. 1846-1855 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Previously infected chimpanzees are not consistently protected against reinfection or persistent infection after reexposure to the identical hepatitis C virus strain.

      Bukh, Jens, Thimme, R., Meunier, J., Faulk, K., Spangenberg, H. C., Chang, K., Satterfield, W., Chisari, F. V. & Purcell, R. H., 2008, In: Journal of Virology. 82, 16, p. 8183-95 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

      Russell, R. S., Meunier, J., Takikawa, S., Faulk, K., Engle, R. E., Bukh, Jens, Purcell, R. H. & Emerson, S. U., 18 Mar 2008, In: PNAS Early Edition. 105, 11, p. 4370-5 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. 2009
    25. Published

      DELETION OF HYPERVARIABLE REGION 1 (HVR1) OF E2 FROM HCV GENOTYPES 1-6 HAS DIFFERENTIAL EFFECT ON INFECTIVITY IN VITRO AND CAUSES INCREASED SUSCEPTIBILITY TO NEUTRALIZATION

      Prentø, Jannick, Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Jensen, T. B., Serre, S. & Bukh, Jens, 2009, In: Journal of Hepatology. 50, p. S34-S34

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs

      Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Jensen, T. B., Lademann, J. B., Prentø, Jannick, Knudsen, M. L., Hoegh, A. M. & Bukh, Jens, 2009, In: Hepatology. 49, 2, p. 364-77 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      MONOCISTRONIC HEPATITIS C REPORTER VIRUS RECOMBINANTS OF ALL MAJOR GENOTYPES EXPRESSING ENHANCED GREEN FLUORESCENT PROTEIN TAGGED NS5A PROTEIN

      Gottwein, Judith Margarete, Lademann, J. B., Scheel, Troels Kasper Høyer, Jensen, T. B., Prentø, Jannick & Bukh, Jens, 2009, In: Journal of Hepatology. 50, p. S33-S33

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles

      Russell, R. S., Kawaguchi, K., Meunier, J., Takikawa, S., Faulk, K., Bukh, Jens, Purcell, R. H. & Emerson, S. U., 2009, In: Journal of Viral Hepatitis. 16, 9, p. 621-32 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Predictors of antiviral treatment initiation in hepatitis C virus-infected patients: a Danish cohort study

      Hansen, N., Obel, N., Christensen, P. B., Krarup, H., Laursen, A. L., Clausen, M. R., Lunding, S., Møller, A., Schlichting, P., Kromann-Andersen, H., Bukh, J., Weis, N., Hansen, N., Obel, N., Christensen, P. B., Krarup, H., Laursen, A. L., Clausen, M. R., Lunding, S., Møller, A. & 4 others, Schlichting, P., Kromann-Andersen, H., Bukh, J. & Weis, Nina, 2009, In: Journal of Viral Hepatitis. 16, 9, p. 659-65 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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    ID: 12437