Bo Torben Porse

Bo Torben Porse

Professor, Clinical Professor

Member of:

  • Internal Medicine: Haematology

ORCID: 0000-0001-6043-0844

Publication year:
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  1. Published

    A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia

    Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, Albin Gustav, Porse, Bo Torben & Theilgaard-Mønch, Kim, Jul 2010, In: Leukemia. 24, 7, p. 1265-75 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

    Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, Jens Vilstrup, Rapin, N. P. J., Porse, Bo Torben, Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Cellular origin of prognostic chromosomal aberrations in AML patients

    Mora-Jensen, H., Jendholm, L. J., Rapin, N. P. J., Andersen, M. K., Roug, A. S., Bagger, F. O., Bullinger, L., Winther, Ole, Borregaard, N., Porse, Bo Torben & Theilgaard-Mønch, Kim, 11 Feb 2015, In: Leukemia. 29, p. 1785-1789 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Technical advance: immunophenotypical characterization of human neutrophil differentiation

    Mora-Jensen, H. I., Jendholm, J., Fossum, A., Porse, Bo Torben, Borregaard, N. & Theilgaard-Mönch, K., 2011, In: Journal of Leukocyte Biology. 90, 3, p. 629-34 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

    Morgan, M., Kabayama, Y., Much, C., Ivanova, I., Di Giacomo, M., Auchynnikava, T., Monahan, J. M., Vitsios, D. M., Vasiliauskaitė, L., Comazzetto, S., Rappsilber, J., Allshire, R. C., Porse, Bo Torben, Enright, A. J. & O'Carroll, D., 2019, In: Cell Research. p. 221–232

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner

    Norrie, I. C., Ohlsson, E., Nielsen, Olaf, Hasemann, M. S. & Porse, Bo Torben, 2014, In: P L o S One. 9, 1, p. 1-9 9 p., e84728.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia

    O'Connor, C., Lohan, F., Campos, J., Ohlsson, E., Salomè, M., Forde, C., Artschwager, R., Liskamp, R. M., Cahill, M. R., Kiely, P. A., Porse, Bo Torben & Keeshan, K., 6 Oct 2016, In: Oncogene. 35, 40, p. 5272-5281 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The multifaceted functions of C/EBPα in normal and malignant haematopoiesis

    Ohlsson, E., Schuster, Mikkel Bruhn, Hasemann, M. & Porse, Bo Torben, Apr 2016, In: Leukemia. 30, 4, p. 767-75 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Initiation of MLL-rearranged AML is dependent on C/EBPα

    Ohlsson, E., Hasemann, M. S., Willer, A., Lauridsen, F. K. B., Rapin, N. P. J., Jendholm, L. J. & Porse, Bo Torben, 13 Jan 2014, In: The Journal of Experimental Medicine. 211, 1, p. 5-13 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

    Pasini, D., Malatesta, M., Jung, H. R., Valfridsson, J. O. A., Willer, A., Olsson, L., Skotte, J., Wutz, A., Porse, Bo Torben, Jensen, O. N. & Helin, K., Aug 2010, In: Nucleic Acids Research. 38, 15, p. 4958-69 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

    Paul, F., Arkin, Y., Giladi, A., Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Winter, D., Lara-Astiaso, D., Gury, M., Weiner, A., David, E., Cohen, N., Lauridsen, F. K. B., Haas, S., Schlitzer, A., Mildner, A., Ginhoux, F., Jung, S., Trumpp, A., Porse, B. T. & 2 others, Tanay, A. & Amit, I., 17 Dec 2015, In: Cell. 163, 7, p. 1663-77 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo.

    Pedersen, T. A., Bereshchenko, O., Garcia-Silva, S., Ermakova, O., Kurz, E., Mandrup, S., Porse, Bo Torben & Nerlov, C., 2007, In: EMBO Journal. 26, 4, p. 1081-93 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition

    Petrosius, V., Aragon-Fernandez, P., Üresin, Nil, Kovacs, G., Phlairaharn, T., Furtwängler, Benjamin, Op De Beeck, J., Skovbakke, S. L., Goletz, S., Thomsen, Simon Francis, Keller, U. A. D., Natarajan, K. N., Porse, Bo Torben & Schoof, E. M., 2023, In: Nature Communications. 14, 16 p., 5910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    UV-induced modifications in the peptidyl transferase loop of 23S rRNA dependent on binding of the streptogramin B antibiotic, pristinamycin IA.

    Porse, Bo Torben, Kirillov, S. V., Awayez, M. J. & Garrett, R. A., 1999, In: RNA: A publication of the RNA Society. 5, 4, p. 585-95 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Antibiotic inhibition of the movement of tRNA substrates through a peptidyl transferase cavity.

    Porse, Bo Torben, Rodriguez-Fonseca, C., Leviev, I. & Garrett, R. A., 1996, In: Biochemistry and Cell Biology. 73, 11-12, p. 877-85 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Mapping important nucleotides in the peptidyl transferase centre of 23 S rRNA using a random mutagenesis approach.

    Porse, Bo Torben & Garrett, R. A., 1995, In: Journal of Molecular Biology. 249, 1, p. 1-10 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.

    Porse, Bo Torben, Kirillov, S. V., Awayez, M. J., Ottenheijm, H. C. & Garrett, R. A., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 16, p. 9003-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre

    Porse, Bo Torben, Leviev, I., Mankin, A. S. & Garrett, R. A., 1998, In: Journal of Molecular Biology. 276, 2, p. 391-404 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The donor substrate site within the peptidyl transferase loop of 23 S rRNA and its putative interactions with the CCA-end of N-blocked aminoacyl-tRNA(Phe).

    Porse, Bo Torben, Thi-Ngoc, H. P. & Garrett, R. A., 1996, In: Journal of Molecular Biology. 264, 3, p. 472-83 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their inhibitory mechanisms.

    Porse, Bo Torben & Garrett, R. A., 1999, In: Journal of Molecular Biology. 286, 2, p. 375-87 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.

    Porse, Bo Torben, Pedersen TA, Xu, X., Lindberg, B., Wewer, Ulla M., Friis-Hansen, L. & Nerlov, C., 2001, In: Cell. 107, 2, p. 247-58 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Ribosomal mechanics, antibiotics, and GTP hydrolysis.

    Porse, Bo Torben & Garrett, R. A., 1999, In: Cell. 97, 4, p. 423-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The antibiotic micrococcin acts on protein L11 at the ribosomal GTPase centre.

    Porse, Bo Torben, Cundliffe, E. & Garrett, Roger Antony, 1999, In: Journal of Molecular Biology. 287, 1, p. 33-45 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Leukemia - methods and protocols

    Porse, Bo Torben, 2009, In: European Journal of Haematology. 84, 1, p. 94

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Basal stamcellebiologi og cancer

    Porse, Bo Torben, Petersen, Ole William & Helin, K., 20 Sep 2010, In: Ugeskrift for læger. 172, 38, p. 2600-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4985646