Anne-Vibeke Lænkholm

Anne-Vibeke Lænkholm

Clinical Associate Professor


  1. Published

    Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy

    Larsen, M. S., Bjerre, K., Lykkesfeldt, A. E., Giobbie-Hurder, A., Lænkholm, Anne-Vibeke, Henriksen, K. L., Ejlertsen, Bent Laursen & Rasmussen, B. B., Oct 2012, In: Breast (Edinburgh, Scotland). 21, 5, p. 662-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Prognostic value of Bcl-2 in two independent populations of estrogen receptor positive breast cancer patients treated with adjuvant endocrine therapy

    Larsen, M. S., Bjerre, K., Giobbie-Hurder, A., Lænkholm, Anne-Vibeke, Henriksen, K. L., Ejlertsen, Bent Laursen, Lykkesfeldt, A. E. & Rasmussen, B. B., Jul 2012, In: Acta Oncologica. 51, 6, p. 781-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment

    Larsen, S. L., Lænkholm, Anne-Vibeke, Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 2015, In: PloS one. 10, 2, e0118346.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer

    Larsen, S. L., Yde, C. W., Lænkholm, Anne-Vibeke, Rasmussen, B. B., Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 8 Apr 2015, In: B M C Cancer. 15, 15 p., 239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry

    Leth-Larsen, R., Lund, Rikke, Hansen, H. V., Lænkholm, Anne-Vibeke, Tarin, D., Jensen, O. N. & Ditzel, H. J., Jun 2009, In: Molecular and Cellular Proteomics. 8, 6, p. 1436-49 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration

    Leung, S. C. Y., Nielsen, T. O., Zabaglo, L., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Enos, R. A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A-V. & 14 others, Lin, M., Mastropasqua, M. G., Moriya, T., Nofech-Mozes, S., Osborne, C. K., Penault-Llorca, F. M., Piper, T., Sakatani, T., Salgado, R., Starczynski, J., Viale, G., Hayes, D. F., McShane, L. M. & Dowsett, M., 2016, In: npj Breast Cancer. 2, p. 16014

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration

    Leung, S. C. Y., Nielsen, T. O., Zabaglo, L. A., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Ehinger, A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A. V., Mastropasqua, M. G. & 15 others, Moriya, T., Nofech-Mozes, S., Osborne, C. K., Penault-Llorca, F. M., Piper, T., Sakatani, T., Salgado, R., Starczynski, J., Sugie, T., van der Vegt, B., Viale, G., Hayes, D. F., McShane, L. M., Dowsett, M. & on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG), O. B. O. T. I. K. I. B. C. W. G. O. T. B. I. G. A. N. A. B. C. G. (., 2019, In: Histopathology. 75, 2, p. 225-235

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    NADH-Cytochrome b5 Reductase 3 Promotes Colonization and Metastasis Formation and Is a Prognostic Marker of Disease-Free and Overall Survival in Estrogen Receptor-Negative Breast Cancer

    Lund, R. R., Leth-Larsen, R., Caterino, T. D., Terp, M. G., Nissen, J., Lænkholm, Anne-Vibeke, Jensen, O. N. & Ditzel, H. J., Nov 2015, In: Molecular and Cellular Proteomics. 14, 11, p. 2988-99 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Quantitative proteomics of primary tumors with varying metastatic capabilities using stable isotope-labeled proteins of multiple histogenic origins

    Lund, Rikke, Terp, M. G., Lænkholm, Anne-Vibeke, Jensen, O. N., Leth-Larsen, R. & Ditzel, H. J., Jul 2012, In: Proteomics. 12, 13, p. 2139-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Williams syndrome transcription factor (WSTF) acts as an activator of estrogen receptor signaling in breast cancer cells and the effect can be abrogated by 1α,25-dihydroxyvitamin D3

    Lundqvist, J., Kirkegaard, T., Lænkholm, Anne-Vibeke, Duun-Henriksen, A. K., Bak, M., Feldman, D. & Lykkesfeldt, A. E., 2018, In: The Journal of Steroid Biochemistry and Molecular Biology. 177, p. 171-178

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Identification of genes for normalization of real-time RT-PCR data in breast carcinomas

    Lyng, M. B., Lænkholm, Anne-Vibeke, Pallisgaard, N. & Ditzel, H. J., 22 Jan 2008, In: BMC Cancer. 8, p. 20

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Intratumor genetic heterogeneity of breast carcinomas as determined by fine needle aspiration and TaqMan low density array

    Lyng, M. B., Lænkholm, Anne-Vibeke, Pallisgaard, N., Vach, W., Knoop, A., Bak, M. & Ditzel, H. J., 2007, In: Analytical Cellular Pathology. 29, 5, p. 361-72 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Gene expression signatures that predict outcome of tamoxifen-treated estrogen receptor-positive, high-risk, primary breast cancer patients: a DBCG study

    Lyng, M. B., Lænkholm, Anne-Vibeke, Tan, Q., Vach, W., Gravgaard, K. H., Knoop, A. & Ditzel, H., 2013, In: PLOS ONE. 8, 1, p. e54078

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The ability of PAM50 risk of recurrence score to predict 10-year distant recurrence in hormone receptor-positive postmenopausal women with special histological subtypes

    Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Buckingham, W., Ferree, S., Nielsen, T. O. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 44-50

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    PAM50 Risk of Recurrence Score Predicts 10-Year Distant Recurrence in a Comprehensive Danish Cohort of Postmenopausal Women Allocated to 5 Years of Endocrine Therapy for Hormone Receptor-Positive Early Breast Cancer

    Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Rasmussen, B. B., Knoop, A. S., Buckingham, W., Ferree, S., Schaper, C., Nielsen, T. O., Haffner, T., Kibøl, T., Møller Talman, M., Bak Jylling, A. M., Tabor, T. P. & Ejlertsen, B., 2018, In: Journal of Clinical Oncology. 36, 8, p. 735-740

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Population-based Study of Prosigna-PAM50 and Outcome Among Postmenopausal Women With Estrogen Receptor-positive and HER2-negative Operable Invasive Lobular or Ductal Breast Cancer

    Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Roslind, A., Buckingham, W., Ferree, S., Nielsen, T. & Ejlertsen, Bent Laursen, Aug 2020, In: Clinical Breast Cancer. 20, 4, p. e423-e432 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit

    Løkkegaard, S., Elias, D., Alves, C. L., Bennetzen, M. V., Lænkholm, Anne-Vibeke, Bak, M., Gjerstorff, M. F., Johansen, L. E., Vever, H., Bjerre, C., Kirkegaard, T., Nordenskjöld, B., Fornander, T., Stål, O., Lindström, L. S., Esserman, L. J., Lykkesfeldt, A. E., Andersen, J. S., Leth-Larsen, R. & Ditzel, H. J., 4 Jan 2021, In: npj Breast Cancer. 7, 1, p. 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

    Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., ABCTB Investigators, Adams, M., Adlard, J. & 27 others, Agata, S., Ahmed, S., Ahsan, H., Aittomäki, K., Al-Ejeh, F., Allen, J., Ambrosone, C. B., Amos, C. I., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Arnold, N., Aronson, K. J., Auber, B., Auer, P. L., Ausems, M. G. E. M., Azzollini, J., Bacot, F., Balmaña, J., Bojesen, Stig Egil, Gerdes, Anne-Marie Axø, Lænkholm, Anne-Vibeke, Nordestgaard, Børge, Schmidt, M. K., Antoniou, A. C. & Simard, J., 2017, In: Nature Genetics. 49, 12, p. 1767-1778

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Breast cancer stem cells: A moving target for cancer nanomedicine

    Mollenhauer, J., Knoop, A., Bak, M., Lænkholm, Anne-Vibeke, Thomassen, M., Kruse, T. A. & Hoilund-Carlsen, P. F., Dec 2012, In: European Journal of Nanomedicine. 4, 2-4, p. 59-72 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Provision of data from the clinical database and of biological material from the tumor bank of the Danish Breast Cancer Cooperative Group 2008–2017

    Mouridsen, H., Christiansen, P., Jensen, M. B., Lænkholm, Anne-Vibeke, Flyger, H., Offersen, B., Vejborg, I. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 154-156 3 p.

    Research output: Contribution to journalComment/debateResearch

  21. Published

    The histology at various stages of acute rejection in concordant xenogeneic heart transplantation: A sequential study in rodents

    NIELSEN, B., STEINBRÜCHEL, D. A., Lænkholm, Anne-Vibeke & KEMP, E., Jan 1992, In: APMIS. 100, 1-6, p. 249-255 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The histology at various stages of acute rejection in concordant xenogeneic heart transplantation. A sequential study in rodents

    Nielsen, B., Steinbrüchel, D. A., Lænkholm, Anne-Vibeke & Kemp, E., Mar 1992, The histology at various stages of acute rejection in concordant xenogeneic heart transplantation. A sequential study in rodents. 3 ed. Vol. 100. p. 249-55 7 p. (APMIS Supplementum).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    The histology at various stages of acute rejection in concordant xenogeneic heart transplantation. A sequential study in rodents

    Nielsen, B., Steinbrüchel, D. A., Lænkholm, Anne-Vibeke & Kemp, E., Mar 1992, In: APMIS Supplementum. 100, 3, p. 249-55 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Amplification of ESR1 may predict resistance to adjuvant tamoxifen in postmenopausal patients with hormone receptor positive breast cancer

    Nielsen, K. V., Ejlertsen, Bent Laursen, Müller, S., Møller, S., Rasmussen, B. B., Balslev, E., Lænkholm, Anne-Vibeke, Christiansen, P. & Mouridsen, H. T., 2011, In: Breast Cancer Research and Treatment. 127, 2, p. 345-355

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Assessment of Ki67 in Breast Cancer: Updated Recommendations from the International Ki67 in Breast Cancer Working Group

    Nielsen, T. O., Leung, S. C. Y., Rimm, D. L., Dodson, A., Acs, B., Badve, S., Denkert, C., Ellis, M. J., Fineberg, S., Flowers, M., Kreipe, H. H., Laenkholm, A-V., Pan, H., Penault-Llorca, F. M., Polley, M-Y., Salgado, R., Smith, I. E., Sugie, T., Bartlett, J. M. S., McShane, L. M. & 2 others, Dowsett, M. & Hayes, D. F., 2021, In: JNCI - Journal of the National Cancer Institute. 113, 7, p. 808–819

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 102813499