Anne-Vibeke Lænkholm
Clinical Associate Professor
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Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy
Larsen, M. S., Bjerre, K., Lykkesfeldt, A. E., Giobbie-Hurder, A., Lænkholm, Anne-Vibeke, Henriksen, K. L., Ejlertsen, Bent Laursen & Rasmussen, B. B., Oct 2012, In: Breast (Edinburgh, Scotland). 21, 5, p. 662-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prognostic value of Bcl-2 in two independent populations of estrogen receptor positive breast cancer patients treated with adjuvant endocrine therapy
Larsen, M. S., Bjerre, K., Giobbie-Hurder, A., Lænkholm, Anne-Vibeke, Henriksen, K. L., Ejlertsen, Bent Laursen, Lykkesfeldt, A. E. & Rasmussen, B. B., Jul 2012, In: Acta Oncologica. 51, 6, p. 781-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment
Larsen, S. L., Lænkholm, Anne-Vibeke, Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 2015, In: PloS one. 10, 2, e0118346.Research output: Contribution to journal › Journal article › Research › peer-review
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Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer
Larsen, S. L., Yde, C. W., Lænkholm, Anne-Vibeke, Rasmussen, B. B., Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 8 Apr 2015, In: B M C Cancer. 15, 15 p., 239.Research output: Contribution to journal › Journal article › Research › peer-review
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Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry
Leth-Larsen, R., Lund, Rikke, Hansen, H. V., Lænkholm, Anne-Vibeke, Tarin, D., Jensen, O. N. & Ditzel, H. J., Jun 2009, In: Molecular and Cellular Proteomics. 8, 6, p. 1436-49 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration
Leung, S. C. Y., Nielsen, T. O., Zabaglo, L., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Enos, R. A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A-V. & 14 others, , 2016, In: npj Breast Cancer. 2, p. 16014Research output: Contribution to journal › Journal article › Research › peer-review
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Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration
Leung, S. C. Y., Nielsen, T. O., Zabaglo, L. A., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Ehinger, A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A. V., Mastropasqua, M. G. & 15 others, , 2019, In: Histopathology. 75, 2, p. 225-235Research output: Contribution to journal › Journal article › Research › peer-review
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NADH-Cytochrome b5 Reductase 3 Promotes Colonization and Metastasis Formation and Is a Prognostic Marker of Disease-Free and Overall Survival in Estrogen Receptor-Negative Breast Cancer
Lund, R. R., Leth-Larsen, R., Caterino, T. D., Terp, M. G., Nissen, J., Lænkholm, Anne-Vibeke, Jensen, O. N. & Ditzel, H. J., Nov 2015, In: Molecular and Cellular Proteomics. 14, 11, p. 2988-99 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomics of primary tumors with varying metastatic capabilities using stable isotope-labeled proteins of multiple histogenic origins
Lund, Rikke, Terp, M. G., Lænkholm, Anne-Vibeke, Jensen, O. N., Leth-Larsen, R. & Ditzel, H. J., Jul 2012, In: Proteomics. 12, 13, p. 2139-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Williams syndrome transcription factor (WSTF) acts as an activator of estrogen receptor signaling in breast cancer cells and the effect can be abrogated by 1α,25-dihydroxyvitamin D3
Lundqvist, J., Kirkegaard, T., Lænkholm, Anne-Vibeke, Duun-Henriksen, A. K., Bak, M., Feldman, D. & Lykkesfeldt, A. E., 2018, In: The Journal of Steroid Biochemistry and Molecular Biology. 177, p. 171-178Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of genes for normalization of real-time RT-PCR data in breast carcinomas
Lyng, M. B., Lænkholm, Anne-Vibeke, Pallisgaard, N. & Ditzel, H. J., 22 Jan 2008, In: BMC Cancer. 8, p. 20Research output: Contribution to journal › Journal article › Research › peer-review
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Intratumor genetic heterogeneity of breast carcinomas as determined by fine needle aspiration and TaqMan low density array
Lyng, M. B., Lænkholm, Anne-Vibeke, Pallisgaard, N., Vach, W., Knoop, A., Bak, M. & Ditzel, H. J., 2007, In: Analytical Cellular Pathology. 29, 5, p. 361-72 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gene expression signatures that predict outcome of tamoxifen-treated estrogen receptor-positive, high-risk, primary breast cancer patients: a DBCG study
Lyng, M. B., Lænkholm, Anne-Vibeke, Tan, Q., Vach, W., Gravgaard, K. H., Knoop, A. & Ditzel, H., 2013, In: PLOS ONE. 8, 1, p. e54078Research output: Contribution to journal › Journal article › Research › peer-review
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The ability of PAM50 risk of recurrence score to predict 10-year distant recurrence in hormone receptor-positive postmenopausal women with special histological subtypes
Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Buckingham, W., Ferree, S., Nielsen, T. O. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 44-50Research output: Contribution to journal › Journal article › Research › peer-review
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PAM50 Risk of Recurrence Score Predicts 10-Year Distant Recurrence in a Comprehensive Danish Cohort of Postmenopausal Women Allocated to 5 Years of Endocrine Therapy for Hormone Receptor-Positive Early Breast Cancer
Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Rasmussen, B. B., Knoop, A. S., Buckingham, W., Ferree, S., Schaper, C., Nielsen, T. O., Haffner, T., Kibøl, T., Møller Talman, M., Bak Jylling, A. M., Tabor, T. P. & Ejlertsen, B., 2018, In: Journal of Clinical Oncology. 36, 8, p. 735-740Research output: Contribution to journal › Journal article › Research › peer-review
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Population-based Study of Prosigna-PAM50 and Outcome Among Postmenopausal Women With Estrogen Receptor-positive and HER2-negative Operable Invasive Lobular or Ductal Breast Cancer
Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Roslind, A., Buckingham, W., Ferree, S., Nielsen, T. & Ejlertsen, Bent Laursen, Aug 2020, In: Clinical Breast Cancer. 20, 4, p. e423-e432 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit
Løkkegaard, S., Elias, D., Alves, C. L., Bennetzen, M. V., Lænkholm, Anne-Vibeke, Bak, M., Gjerstorff, M. F., Johansen, L. E., Vever, H., Bjerre, C., Kirkegaard, T., Nordenskjöld, B., Fornander, T., Stål, O., Lindström, L. S., Esserman, L. J., Lykkesfeldt, A. E., Andersen, J. S., Leth-Larsen, R. & Ditzel, H. J., 4 Jan 2021, In: npj Breast Cancer. 7, 1, p. 2Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., ABCTB Investigators, Adams, M., Adlard, J. & 27 others, , 2017, In: Nature Genetics. 49, 12, p. 1767-1778Research output: Contribution to journal › Journal article › Research › peer-review
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Breast cancer stem cells: A moving target for cancer nanomedicine
Mollenhauer, J., Knoop, A., Bak, M., Lænkholm, Anne-Vibeke, Thomassen, M., Kruse, T. A. & Hoilund-Carlsen, P. F., Dec 2012, In: European Journal of Nanomedicine. 4, 2-4, p. 59-72 14 p.Research output: Contribution to journal › Review › Research › peer-review
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Provision of data from the clinical database and of biological material from the tumor bank of the Danish Breast Cancer Cooperative Group 2008–2017
Mouridsen, H., Christiansen, P., Jensen, M. B., Lænkholm, Anne-Vibeke, Flyger, H., Offersen, B., Vejborg, I. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 154-156 3 p.Research output: Contribution to journal › Comment/debate › Research
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The histology at various stages of acute rejection in concordant xenogeneic heart transplantation: A sequential study in rodents
NIELSEN, B., STEINBRÜCHEL, D. A., Lænkholm, Anne-Vibeke & KEMP, E., Jan 1992, In: APMIS. 100, 1-6, p. 249-255 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The histology at various stages of acute rejection in concordant xenogeneic heart transplantation. A sequential study in rodents
Nielsen, B., Steinbrüchel, D. A., Lænkholm, Anne-Vibeke & Kemp, E., Mar 1992, The histology at various stages of acute rejection in concordant xenogeneic heart transplantation. A sequential study in rodents. 3 ed. Vol. 100. p. 249-55 7 p. (APMIS Supplementum).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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The histology at various stages of acute rejection in concordant xenogeneic heart transplantation. A sequential study in rodents
Nielsen, B., Steinbrüchel, D. A., Lænkholm, Anne-Vibeke & Kemp, E., Mar 1992, In: APMIS Supplementum. 100, 3, p. 249-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amplification of ESR1 may predict resistance to adjuvant tamoxifen in postmenopausal patients with hormone receptor positive breast cancer
Nielsen, K. V., Ejlertsen, Bent Laursen, Müller, S., Møller, S., Rasmussen, B. B., Balslev, E., Lænkholm, Anne-Vibeke, Christiansen, P. & Mouridsen, H. T., 2011, In: Breast Cancer Research and Treatment. 127, 2, p. 345-355Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of Ki67 in Breast Cancer: Updated Recommendations from the International Ki67 in Breast Cancer Working Group
Nielsen, T. O., Leung, S. C. Y., Rimm, D. L., Dodson, A., Acs, B., Badve, S., Denkert, C., Ellis, M. J., Fineberg, S., Flowers, M., Kreipe, H. H., Laenkholm, A-V., Pan, H., Penault-Llorca, F. M., Polley, M-Y., Salgado, R., Smith, I. E., Sugie, T., Bartlett, J. M. S., McShane, L. M. & 2 others, , 2021, In: JNCI - Journal of the National Cancer Institute. 113, 7, p. 808–819Research output: Contribution to journal › Journal article › Research › peer-review
ID: 102813499
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Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression
Research output: Contribution to journal › Journal article › Research › peer-review
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The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
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Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence
Research output: Contribution to journal › Journal article › Research › peer-review
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