Mads Hornum

Mads Hornum

Clinical Professor

Member of:

  • Internal Medicine: Nephrology


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  1. Published

    Drug Dosing and Estimated Renal Function: Any Step Forward from Effersoe?

    Hornum, Mads & Feldt-Rasmussen, Bo, 2017, In: Nephron. 136, 4, p. 268-272 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    Further perspectives on statin use in patients with chronic kidney disease

    Houlind, Morten Baltzer, Iversen, E., Andersen, A., Juul-Larsen, H. G., Carlson, N., Andersen, Ove & Hornum, Mads, 2022, In: Basic and Clinical Pharmacology and Toxicology. 131, 5, p. 303-305

    Research output: Contribution to journal › Letter › Research › peer-review

  3. Published

    Performance of the 2009 CKDEPI, 2021 CKDEPI, and EKFC equations among high-risk patients in Denmark

    Houlind, Morten Baltzer, Iversen, E., Curovic, V. R., Jørgensen, M. B., Andersen, A., Gustafsson, Finn, Nelson, L. M. S., Perch, Michael, Damgaard, Morten, Persson, F., Feldt-Rasmussen, Bo, Andersen, Ove, Lund, Trine Meldgaard & Hornum, Mads, 2023, In: Clinical Chemistry and Laboratory Medicine. 61, 10, p. e192-e195

    Research output: Contribution to journal › Letter › Research › peer-review

  4. Published

    Machine Learning to Identify Patients at Risk of Inappropriate Dosing for Renal Risk Medications: A Critical Comment on Kaas-Hansen et al [Letter]

    Houlind, Morten Baltzer, Iversen, E., Jawad, B. N., Kallemose, T. & Hornum, Mads, 2022, In: Clinical Epidemiology. 14, p. 763-764

    Research output: Contribution to journal › Letter › Research › peer-review

  5. Published

    Effect of liraglutide treatment on jejunostomy output in patients with short bowel syndrome: An open-label pilot study

    Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R. M., Hartmann, Bolette, Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, Mads, Andersen, Jens Rikardt, Henriksen, B. M., Brøbech Mortensen, P. & Jeppesen, Palle Bekker, 2018, In: Journal of Parenteral and Enteral Nutrition. 42, 1, p. 112-121 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded, parallel intervention study

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 26 Apr 2013, In: B M J Open. 3, 4, p. 1-10 11 p., e002764.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Christensen, Mikkel Bring, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 8 Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 7, p. 2457-66 10 p., jc20133809.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The authors reply

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  10. Published

    Gastrointestinal factors contribute to glucometabolic disturbances in nondiabetic patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, May 2013, In: Kidney International. 83, 5, p. 915-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Safety and Efficacy of Liraglutide in Patients With Type 2 Diabetes and End-Stage Renal Disease: An Investigator-Initiated, Placebo-Controlled, Double-Blinded, Parallel Group, Randomized Trial

    Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Feb 2016, In: Diabetes Care. 39, 2, p. 206-13 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Soluble urokinase plasminogen activator receptor and decline in kidney function among patients without kidney disease

    Iversen, E., Kallemose, T., Hornum, Mads, Bengaard, A. K., Nehlin, J. O., Rasmussen, L. J. H., Sandholdt, H., Tavenier, J., Feldt-Rasmussen, Bo, Andersen, Ove, Eugen-Olsen, J. & Houlind, Morten Baltzer, 2022, In: Clinical Kidney Journal. 15, 8, p. 1534-1541

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Performance of Panel-Estimated GFR Among Hospitalized Older Adults

    Iversen, E., Bengaard, A. K., Leegaard Andersen, A., Tavenier, J., Nielsen, R. L., Juul-Larsen, H. G., Jørgensen, L. M., Bornæs, O., Jawad, B. N., Aharaz, A., Walls, Anne Byriel, Kallemose, T., Dalhoff, Kim, Nehlin, J. O., Hornum, Mads, Feldt-Rasmussen, Bo, Damgaard, Morten, Andersen, Ove & Houlind, Morten Baltzer, 2023, In: American Journal of Kidney Diseases. 82, 6, p. 715-724 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    In Reply to Estimating GFR: The Devil Is in the Details

    Iversen, E., Hornum, Mads & Houlind, Morten Baltzer, 2024, In: American Journal of Kidney Diseases. 83, 2, p. 268-269 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  15. Published

    Performance of the Cockcroft-Gault, Modification of Diet in Renal Disease, and new Chronic Kidney Disease Epidemiology Collaboration equations without race in older acute medical patients

    Iversen, E., Bengaard, A. K., Andersen, A., Kallemose, T., Damgaard, Morten, Hornum, Mads, Feldt-Rasmussen, Bo, Andersen, Ove & Houlind, Morten Baltzer, 2022, In: Kidney International. 101, 5, p. 1087-1088

    Research output: Contribution to journal › Letter › Research › peer-review

  16. Published

    Elevated suPAR Is an Independent Risk Marker for Incident Kidney Disease in Acute Medical Patients

    Iversen, E., Houlind, M. B., Kallemose, T., Rasmussen, L. J. H., Hornum, Mads, Feldt-Rasmussen, Bo, Hayek, S. S., Andersen, Ove & Eugen-Olsen, J., 2020, In: Frontiers in Cell and Developmental Biology. 8, 9 p., 339.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Comparison of Measured and Estimated GFR for Rivaroxaban Dosing in Hospitalized Older Adults

    Iversen, E., Hornum, Mads & Houlind, Morten Baltzer, 2023, In: American Journal of Kidney Diseases. 83, 1, p. 117-118 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  18. Published

    Comment on Delanaye et al: Future perspectives regarding kidney function estimates and dose adjustments

    Iversen, E., Hornum, Mads, Lund, Trine Meldgaard & Houlind, Morten Baltzer, 2022, In: British Journal of Clinical Pharmacology. 88, 6, p. 2998-2999

    Research output: Contribution to journal › Letter › Research › peer-review

  19. Published

    Reply to: Correspondence regarding the impact of kidney transplantation on insulin sensitivity

    Jørgensen, M. B., Hornum, Mads, van Hall, G., Bistrup, C., Hansen, Jesper Melchior, Mathiesen, Elisabeth & Feldt-Rasmussen, Bo, 2018, In: Transplant International. 31, 4, p. 458-459

    Research output: Contribution to journal › Comment/debate › Research

  20. Published

    Clearance of glucoregulatory peptide hormones during haemodialysis and haemodiafiltration in non-diabetic end-stage renal disease patients

    Jørgensen, M. B., Idorn, T., Knop, Filip Krag, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Mar 2015, In: Nephrology, Dialysis, Transplantation. 30, 3, p. 513-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The impact of kidney transplantation on insulin sensitivity

    Jørgensen, M. B., Hornum, Mads, van Hall, G., Bistrup, C., Hansen, Jesper Melchior, Mathiesen, Elisabeth & Feldt-Rasmussen, Bo, Mar 2017, In: Transplant International. 30, 3, p. 295-304 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Effect of the Incretin Hormones on the Endocrine Pancreas in End-Stage Renal Disease

    Jørgensen, M. B., Idorn, T., Rydahl, C., Hansen, H. P., Bressendorff, I., Brandi, Lisbet, Wewer Albrechtsen, N. J., van Hall, Gerrit, Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e564-e574

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Sodium-glucose cotransporter 2 inhibitors for diabetes mellitus control after kidney transplantation: Review of the current evidence

    Kanbay, M., Demiray, A., Afsar, B., Karakus, K. E., Ortiz, A., Hornum, Mads, Covic, A., Sarafidis, P. & Rossing, Peter, 2021, In: Nephrology. 26, 12, p. 1007-1017

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency

    Knop, Filip Krag, Vilsbøll, Tina, Lund, A., Krarup, T., Holst, Jens Juul & Hornum, Mads, 6 Sep 2010, In: Journal of the Pancreas. 11, 5, p. 489-91 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Micro- and macrovascular complications and risk factors for foot ulceration and amputation in individuals receiving dialysis with and without diabetes

    Kofod, D. H., Almdal, Thomas Peter, Sørensen, V. R., Feldt-Rasmussen, Bo & Hornum, Mads, 2022, In: Endocrinology, Diabetes and Metabolism. 5, 1, e00305.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Cardiac arrhythmia and hypoglycaemia in patients receiving haemodialysis with and without diabetes (the CADDY study): Protocol for a Danish multicentre cohort study

    Kofod, D. H., Diederichsen, S. Z., Bomholt, T., Ørbæk Andersen, M., Rix, M., Liem, Y., Lindhard, K., Post Hansen, H., Rydahl, C., Lindhardt, Morten Kofod, Schandorff, K., Lange, Theis, Nørgaard, Kirsten, Almdal, Thomas Peter, Svendsen, Jesper Hastrup, Feldt-Rasmussen, Bo & Hornum, Mads, 2023, In: BMJ Open. 13, 10, 7 p., e077063.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Cardiovascular mortality in patients with advanced chronic kidney disease with and without diabetes: a nationwide cohort study

    Kofod, D. H., Carlson, N., Ballegaard, E. F., Almdal, Thomas Peter, Torp-Pedersen, Christian, Gislason, Gunnar Hilmar, Svendsen, Jesper Hastrup, Feldt-Rasmussen, Bo & Hornum, Mads, 2023, In: Cardiovascular Diabetology. 22, 1, 11 p., 140.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Cannabisolieinduceret diabetes mellitus

    Lindhard, K. & Hornum, Mads, 2018, In: Ugeskrift for Laeger. 180, 44, 2 p., V04180370.

    Research output: Contribution to journal › Letter › Research › peer-review

  29. Published

    Non-adherence, medication beliefs and symptom burden among patients receiving hemodialysis -a cross-sectional study

    Mechta Nielsen, T., Marott, T., Hornum, Mads, Feldt-Rasmussen, Bo, Kallemose, T. & Thomsen, Thordis, 2023, In: BMC Nephrology. 24, 1, 10 p., 321.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Practices and pitfalls in medication adherence in hemodialysis settings – a focus-group study of health care professionals

    Mechta Nielsen, T., Schjerning, N., Kaldan, G., Hornum, Mads, Feldt-Rasmussen, Bo & Thomsen, Thordis, 2021, In: BMC Nephrology. 22, 9 p., 315.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Roles of NAD+ in Acute and Chronic Kidney Diseases

    Morevati, M., Fang, E. F., Mace, M. L., Kanbay, M., Gravesen, E., Nordholm, A., Egstrand, S. & Hornum, Mads, 2023, In: International Journal of Molecular Sciences. 24, 1, 137.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Appetite stimulation with cannabis-based medicine and methods for assessment of glomerular filtration in older patients with medical illness: A study protocol

    Nielsen, R. L., Bornæs, O., Storgaard, I. K., Kallemose, T., Jørgensen, L. M., Jawad, B. N., Altintas, I., Juul-larsen, H. G., Tavenier, J., Durhuus, J. A., Bengaard, A. K. P., Holst, J. J., Kolko, M., Sonne, D. P., Breindahl, T., Damgaard, M., Porrini, E., Hornum, M., Andersen, O., Pedersen, M. M. & 6 others, Rasmussen, H. H., Munk, T., Lund, Trine Meldgaard, Jensen, A. P. S. L., Andersen, A. L. & Houlind, Morten Baltzer, 2023, In: Basic & Clinical Pharmacology & Toxicology. 133, 3, p. 237-253 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Decreased glomerular function is associated with disease severity in patients with hidradenitis suppurativa

    Nielsen, V. W., Yao, Y., Holm, J. G., Jørgensen, A. H. R., Ring, H. C., Hornum, Mads & Thomsen, Simon Francis, 2022, In: Health Science Reports. 5, 2, e535.

    Research output: Contribution to journal › Letter › Research › peer-review

  34. Published

    A Pilot Study Showing Acute Inhibitory Effect of GLP-1 on the Bone Resorption Marker CTX in Humans

    Nissen, A., Marstrand, S., Skov-Jeppesen, Kirsa, Bremholm, L., Hornum, Mads, Andersen, U. B., Holst, Jens Juul, Rosenkilde, M. M. & Hartmann, Bolette, 2019, In: JBMR Plus. 3, 10, 6 p., e10209.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Does glyceryl nitrate prevent post-ERCP pancreatitis? A prospective, randomized, double-blind, placebo-controlled multicenter trial

    Nøjgaard, C., Hornum, Mads, Elkjaer, M., Hjalmarsson, C., Heyries, L., Hauge, T., Bakkevold, K., Andersen, Per Kragh, Matzen, P., European Post-ERCP Pancreatitis Preventing Study Group, E. P. P. P. S. G., Nøjgaard, C., Hornum, M., Elkjaer, M., Hjalmarsson, C., Heyries, L., Hauge, T., Bakkevold, K., Andersen, P. K., Matzen, P. & NN, N., 2009, In: Gastrointestinal Endoscopy. 69, 6, p. e31-7

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Cyclosporine and COVID-19: Risk or favorable?

    Poulsen, N. N., von Brunn, A., Hornum, Mads & Blomberg Jensen, M., 2020, In: American Journal of Transplantation. 20, 11, p. 2975-2982 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Post-Transplant Diabetes Mellitus and Prediabetes in Renal Transplant Recipients: An Update

    Rodríguez-Rodríguez, A. E., Porrini, E., Hornum, Mads, Donate-Correa, J., Morales-Febles, R., Khemlani Ramchand, S., Molina Lima, M. X. & Torres, A., 2021, In: Nephron. 145, 4, p. 317-329 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    The Role of Vascular Lesions in Diabetes Across a Spectrum of Clinical Kidney Disease

    Rodríguez-Rodríguez, R., Hojs, R., Trevisani, F., Morales, E., Fernández, G., Bevc, S., Cases Corona, C. M., Cruzado, J. M., Quero, M., Navarro Díaz, M., Bettiga, A., Di Marco, F., López Martínez, M., Moreso, F., García Garro, C., Khazim, K., Ghanem, F., Praga, M., Ibernón, M., Laranjinha, I. & 10 others, Mendonça, L., Bigotte Vieira, M., Hornum, Mads, Feldt-Rasmussen, Bo, Fernández-Fernández, B., Concepción, P. F., Negrín Mena, N., Ortiz, A., Porrini, E. & DIABESITY working group of the ERA, D. W. G. O. T. E., 2021, In: Kidney International Reports. 6, 9, p. 2392-2403 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    SGLT-2 inhibitors and GLP-1 receptor agonists for nephroprotection and cardioprotection in patients with diabetes mellitus and chronic kidney disease. A consensus statement by the EURECA-m and the DIABESITY working groups of the ERA-EDTA

    Sarafidis, P., Ferro, C. J., Morales, E., Ortiz, A., Malyszko, J., Hojs, R., Khazim, K., Ekart, R., Valdivielso, J., Fouque, D., London, G. M., Massy, Z., Ruggenenti, P., Porrini, E., Wiecek, A., Zoccali, C., Mallamaci, F. & Hornum, Mads, 2019, In: Nephrology Dialysis Transplantation. 34, 2, p. 208-230 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Behandling af metforminassocieret laktatacidose med hæmodialyse

    Schousboe, K., Rasmussen, K., Fassi, Daniel El , Secher, E. L., Elming, H. & Hornum, Mads, 1 Jan 2012, In: Ugeskrift for Laeger. 174, 23, p. 1604-1606 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Circulating Levels of Endotrophin Are Prognostic for Long-Term Mortality after AKI

    Sparding, N., Rasmussen, D. G. K., Genovese, F., Karsda, M. A., Hornum, Mads, Feldt-Rasmussen, Bo, Packington, R. & Selby, N. M., 2022, In: Kidney360. 3, 5, p. 809-817 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Endotrophin Levels Are Associated with Allograft Outcomes in Kidney Transplant Recipients

    The CONTEXT Study Group, T. C. S. G., 2023, In: Biomolecules. 13, 5, 13 p., 792.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Endotrophin, a collagen type VI-derived matrikine, reflects the degree of renal fibrosis in patients with IgA nephropathy and in patients with ANCA-associated vasculitis

    Sparding, N., Genovese, F., Rasmussen, D. G. K., Karsdal, M. A., Neprasova, M., Maixnerova, D., Satrapova, V., Frausova, D., Hornum, Mads, Bartonova, L., Honsova, E., Kollar, M., Koprivova, H., Hruskova, Z. & Tesar, V., 2022, In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 37, 6, p. 1099-1108

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Metabolically healthy obesity: Misleading phrase or healthy phenotype?

    Tanriover, C., Copur, S., Gaipov, A., Ozlusen, B., Akcan, R. E., Kuwabara, M., Hornum, Mads, Van Raalte, D. H. & Kanbay, M., 2023, In: European Journal of Internal Medicine. 111, p. 5-20 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Characterization of Hyperreflective Dots by Structural and Angiographic Optical Coherence Tomography in Patients with Diabetic Retinopathy and Healthy Subjects

    Torm, M. E. W., Sander, B., Hornum, Mads, Krohn, P., Birn, H. & Larsen, Michael, 2022, In: Journal of Clinical Medicine. 11, 22, 6646.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Intravascular volumes and the influence on anemia assessed by a carbon monoxide rebreathing method in patients undergoing maintenance hemodialysis

    Vinje, V., Bomholt, T., Lundby, C., Oturai, P., Rix, M., Lindhard, K. & Hornum, Mads, 2024, In: Hemodialysis International. 28, 1, p. 40-50 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Techniques to Assess the Effect of Sodium-Glucose Cotransporter 2 Inhibitors on Blood Volume in Patients with Diabetic Kidney Disease

    Vinje, V., Bomholt, T., Rossing, Peter, Lundby, C., Oturai, P. & Hornum, Mads, 2024, In: Nephron. 148, 3, p. 137-142 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Prognostic value of contralateral suppression on kidney function after surgery in patients with primary aldosteronism

    Voss, N., Mørup, S., Clausen, C., Feltoft, C. L., Jepsen, Jan Viberg, Hornum, Mads, Andreassen, Mikkel & Krogh, Jesper, 2023, In: Clinical Endocrinology. 98, 3, p. 306-314

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Utility of suPAR and NGAL for AKi risk stratification and early optimization of renal risk medications among older patients in the emergency department

    Walls, Anne Byriel, Bengaard, A. K., Iversen, E., Nguyen, C. N., Kallemose, T., Juul‐larsen, H. G., Jawad, B. N., Hornum, Mads, Andersen, Ove, Eugen‐olsen, J. & Houlind, M. B., 2021, In: Pharmaceuticals. 14, 9, 15 p., 843.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

    dos Santos, Q., Leung, P., Thorball, C. W., Ledergerber, B., Fellay, J., MacPherson, C. R., Hornum, Mads, Terrones-Campos, C., Rasmussen, A., Gustafsson, Finn, Perch, Michael, Sørensen, Søren Schwartz, Ekenberg, C., Lundgren, Jens, Feldt-Rasmussen, Bo & Reekie, J., 2023, In: Frontiers in Molecular Biosciences. 10, 10 p., 1282412.

    Research output: Contribution to journal › Journal article › Research › peer-review

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