Hans K Hasselbalch
Clinical Professor
Department of Clinical Medicine
Køgevej 7 - 13, 4000 Roskilde
Member of:
Internal Medicine: Haematology
- Published
Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms
Andersen, Christen Bertel L, Grønbæk, Kirsten & Hasselbalch, Hans Carl, 1 Apr 2012, In: Leukemia Research. 36, 4, p. 485-487 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of the blood eosinophil count with hematological malignancies and mortality
Andersen, Christen Bertel L, Siersma, Volkert Dirk, Hasselbalch, Hans Carl, Vestergaard, H., Mesa, R., Felding, P., Olivarius, Niels de Fine & Bjerrum, O. W., Mar 2015, In: American Journal of Hematology. 90, 3, p. 225-229 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Somatic mutations of the CREBBP and EP300 genes affect response to histone deacetylase inhibition in malignant DLBCL clones
Andersen, Christen Bertel L, Asmar, F., Klausen, T., Hasselbalch, Hans Carl & Grønbæk, K., 2012, In: Leukemia Research Reports. 2, 1, p. 1-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome
Andersen, Christen Bertel L, Nielsen, H. M., Sommer Kristensen, L., Helbo, A. S., Vikeså, J., Jønson, L., Nielsen, Finn Cilius, Hasselbalch, Hans Carl, Bjerrum, O. W., Punj, V. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 38, p. 40588-97 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Myeloproliferative Neoplasms in Danish Twins
Andersen, M. A., Bjerrum, O. W., Ranjan, A., Skov, V., Kruse, T. A., Thomassen, M., Skytthe, A., Hasselbalch, Hans Carl & Christensen, K., 2018, In: Acta Haematologica. 139, 3, p. 195-198 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development
Andersen, M., Sajid, Z., Pedersen, R. K., Gudmand-hoeyer, J., Ellervik, C., Skov, V., Kjær, L., Pallisgaard, N., Kruse, T. A., Thomassen, M., Troelsen, J., Hasselbalch, Hans Carl & Ottesen, J. T., 2017, In: PLOS ONE. 12, 8, 18 p., e0183620.Research output: Contribution to journal › Journal article › Research › peer-review
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Age-Related Macular Degeneration in Patients With Chronic Myeloproliferative Neoplasms
Bak, M., Sørensen, Torben Lykke, Flachs, E. M., Zwisler, A., Juel, K., Frederiksen, H. & Hasselbalch, Hans Carl, 2017, In: JAMA Ophthalmology. 135, 8, p. 835-843Research output: Contribution to journal › Journal article › Research › peer-review
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Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European leukemiaNet
Barbui, T., Barosi, G., Birgegard, G., Cervantes, F., Finazzi, G., Griesshammer, M., Harrison, C., Hasselbalch, H. C., Hehlmann, R., Hoffman, R., Kiladjian, J-J., Kröger, N., Mesa, R., McMullin, M. F., Pardanani, A., Passamonti, F., Vannucchi, A. M., Reiter, A., Silver, R. T., Verstovsek, S. & 1 others, , 20 Feb 2011, In: Journal of Clinical Oncology. 29, 6, p. 761-770 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Philadelphia chromosome-negative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet
Barbui, T., Tefferi, A., Vannucchi, A. M., Passamonti, F., Silver, R. T., Hoffman, R., Verstovsek, S., Mesa, R., Kiladjian, J-J., Hehlmann, R., Reiter, A., Cervantes, F., Harrison, C., Mc Mullin, M. F., Hasselbalch, H. C., Koschmieder, S., Marchetti, M., Bacigalupo, A., Finazzi, G., Kroeger, N. & 3 others, , 2018, In: Leukemia. 32, 5, p. 1057-1069Research output: Contribution to journal › Review › Research › peer-review
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Inflammatory functional iron deficiency common in myelofibrosis, contributes to anaemia and impairs quality of life. From the Nordic MPN study Group
Birgegard, G., Samuelsson, J., Ahlstrand, E., Ejerblad, E., Enevold, C., Ghanima, W., Hasselbalch, Hans Carl, Nielsen, Claus Henrik, Knutsen, H., Pedersen, Ole Birger Vesterager, Sørensen, A. & Andreasson, B., 2019, In: European Journal of Haematology. 102, 3, p. 235-240Research output: Contribution to journal › Journal article › Research › peer-review
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Association of the blood eosinophil count with end-organ symptoms
Bjerrum, O. W., Siersma, Volkert Dirk, Hasselbalch, Hans Carl, Lind, B. & Andersen, Christen Bertel L, 2019, In: Annals of Medicine and Surgery. 45, p. 11-18Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating YKL-40 in myelofibrosis a potential novel biomarker of disease activity and the inflammatory state
Bjørn, M. E., Andersen, Christen Bertel L, Jensen, M. K. & Hasselbalch, Hans Carl, 2014, In: European Journal of Haematology. 93, 3, p. 224-228 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ruxolitinib treatment reduces monocytic superoxide radical formation without affecting hydrogen peroxide formation or systemic oxidative nucleoside damage in myelofibrosis
Bjørn, M. E., Brimnes, M. K., Gudbrandsdottir, S., Andersen, C. L., Poulsen, Henrik Enghusen, Henriksen, T., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, Oct 2019, In: Leukemia and Lymphoma. 60, 10, p. 2549-2557 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Minimal residual disease or cure in MPNs? Rationales and perspectives on combination therapy with interferon-alpha2 and ruxolitinib
Bjørn, M. E. & Hasselbalch, Hans Carl, 2017, In: Expert Review of Hematology. 10, 5, p. 393-404Research output: Contribution to journal › Review › Research › peer-review
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Anxiety and depression in patients with Philadelphia-negative myeloproliferative neoplasms: a nationwide population-based survey in Denmark
Brochmann, N., Flachs, E. M., Christensen, A. I., Bak, M., Andersen, Christen Bertel L, Juel, K., Hasselbalch, Hans Carl, Zwisler, A. & Rottmann, N., 2019, In: Clinical Epidemiology. 11, p. 23-33Research output: Contribution to journal › Journal article › Research › peer-review
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A nationwide population-based cross-sectional survey of health-related quality of life in patients with myeloproliferative neoplasms in Denmark (MPNhealthSurvey): survey design and characteristics of respondents and nonrespondents
Brochmann, N., Flachs, E. M., Christensen, A. I., Andersen, Christen Bertel L, Juel, K., Hasselbalch, Hans Carl & Zwisler, A., 2017, In: Clinical Epidemiology. 9, p. 141-150Research output: Contribution to journal › Journal article › Research › peer-review
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A new internet-based tool for reporting and analysing patient-reported outcomes and the feasibility of repeated data collection from patients with myeloproliferative neoplasms
Brochmann, N., Zwisler, A., Kjerholt, M., Flachs, E. M., Hasselbalch, Hans Carl & Andersen, Christen Bertel L, 2016, In: Quality of Life Research. 25, 4, p. 835-846 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Patients With Myeloproliferative Neoplasms Harbor High Frequencies of CD8 T Cell-Platelet Aggregates Associated With T Cell Suppression
Carnaz Simões, A. M., Holmström, M. O., Aehnlich, P., Rahbech, Anne, Radziwon-Balicka, A., Zamora, C., Wirenfeldt Klausen, T., Skov, V., Kjær, L., Ellervik, Christina, Fassi, Daniel El , Vidal, S., Hasselbalch, Hans Carl, Andersen, Mads Hald & thor Straten, P., 2022, In: Frontiers in Immunology. 13, 866610.Research output: Contribution to journal › Journal article › Research › peer-review
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Tobacco use in the Myeloproliferative neoplasms: symptom burden, patient opinions, and care
Christensen, S. F., Scherber, R. M., Mazza, G. L., Dueck, A. C., Brochmann, N., Andersen, Christen Bertel L, Hasselbalch, Hans Carl, Mesa, R. A. & Geyer, H. L., 2021, In: BMC Cancer. 21, 1, 13 p., 691.Research output: Contribution to journal › Journal article › Research › peer-review
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Healthcare resource utilization in patients with myeloproliferative neoplasms: A Danish nationwide matched cohort study
Christensen, S. F., Svingel, L. S., Kjaersgaard, A., Stenling, A., Darvalics, B., Paulsson, B., Andersen, Christen Bertel L, Christiansen, C. F., Stentoft, J., Starklint, J., Severinsen, M. T., Clausen, M. B., Hilsoe, M. H., Hasselbalch, Hans Carl, Frederiksen, H., Mikkelsen, E. M. & Bak, M., 2022, In: European Journal of Haematology. 109, 5, p. 526-541 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early detection of myeloproliferative neoplasms in a Danish general population study
Cordua, S., Kjaer, L., Skov, V., Pallisgaard, N., Kefala, Maria, Gjerdrum, Lise Mette Rahbek, Hasselbalch, Hans Carl & Ellervik, Christina, 2021, In: Leukemia. 35, 9, p. 2706-2709 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence and phenotypes of JAK2 V617F and calreticulin mutations in a Danish general population
Cordua, S., Kjaer, L., Skov, V., Pallisgaard, N., Hasselbalch, Hans Carl & Ellervik, Christina, 2019, In: Blood. 134, 5, p. 469-479Research output: Contribution to journal › Journal article › Research › peer-review
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JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation
Czech, J., Cordua, S., Weinbergerova, B., Baumeister, J., Crepcia, A., Han, L., Maié, T., Costa, I. G., Denecke, B., Maurer, A., Schubert, C., Feldberg, K., Gezer, D., Brümmendorf, T. H., Müller-newen, G., Mayer, J., Racil, Z., Kubesova, B., Knudsen, T., Sørensen, A. L. & 7 others, , 2019, In: Leukemia. 33, 4, p. 995-1010Research output: Contribution to journal › Journal article › Research › peer-review
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A novel integrated biomarker index for the assessment of hematological responses in MPNs during treatment with hydroxyurea and interferon-alpha2
Dam, M. J. B., Pedersen, R. K., Knudsen, T. A., Andersen, M., Ellervik, Christina, Larsen, Morten Kranker, Kjær, L., Skov, V., Hasselbalch, Hans Carl & Ottesen, J. T., 2023, In: Cancer Medicine. 12, 4, p. 4218-4226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis
Dam, M. J. B., Pedersen, R. K., Knudsen, T. A., Andersen, M., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Ottesen, J. T., 2021, In: European Journal of Haematology. 107, 6, p. 624-633 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 2849472
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A nationwide population-based cross-sectional survey of health-related quality of life in patients with myeloproliferative neoplasms in Denmark (MPNhealthSurvey): survey design and characteristics of respondents and nonrespondents
Research output: Contribution to journal › Journal article › Research › peer-review
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Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations
Research output: Contribution to journal › Journal article › Research › peer-review
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137
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Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development
Research output: Contribution to journal › Journal article › Research › peer-review
Published