Lena Specht
Clinical Professor
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Development and validation of a cycle-specific risk score for febrile neutropenia during chemotherapy cycles 2-6 in patients with solid cancers: The CSRFENCE score
Aagaard, T., Reekie, J., Roen, A., Daugaard, G., Specht, Lena, Sengeløv, Henrik, Mocroft, A., Lundgren, Jens & Helleberg, M., 15 Jan 2020, In: International Journal of Cancer. 146, 2, p. 321-328 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mortality and admission to intensive care units after febrile neutropenia in patients with cancer
Aagaard, T., Reekie, J., Jørgensen, M., Roen, A., Daugaard, G., Specht, Lena, Sengeløv, Henrik, Mocroft, A., Lundgren, Jens & Helleberg, M., May 2020, In: Cancer Medicine. 9, 9, p. 3033-3042 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improved prognosis for localized malignant lymphomas of the head and neck
Aanæs, Kasper, Kristensen, E., Ralfkiær, E. M., von Buchwald, Christian, Specht, Lena, Aanæs, Kasper, Kristensen, E., Ralfkiaer, E. M., von Buchwald, C. & Specht, Lena, 1 May 2010, In: Acta Oto-Laryngologica. 130, 5, p. 626-31 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of different lung densities on the accuracy of various radiotherapy dose calculation methods: implications for tumour coverage
Aarup, L. R., Nahum, A. E., Zacharatou, C., Juhler-Nøttrup, T., Knöös, T., Nyström, H., Specht, Lena, Wieslander, E., Korreman, S. S., Aarup, L. R., Nahum, A. E., Zacharatou, C., Juhler-Nøttrup, T., Knöös, T., Nyström, H., Specht, Lena, Wieslander, E. & Korreman, S., 1 Jun 2009, In: Radiotherapy & Oncology. 91, 3, p. 405-14 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extranodal NK/T-cell lymphoma, nasal type, with extranasal presentation–a case report and a review of the literature
Akbar, M., Clasen-Linde, E. & Specht, Lena, 2020, In: Acta Oncologica. p. 1-8 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Early positron emission tomography response-adapted treatment in stage I and II hodgkin lymphoma: Final results of the randomized EORTC/LYSA/FIL H10 trial
André, M. P. E., Girinsky, T., Federico, M., Reman, O., Fortpied, C., Gotti, M., Casasnovas, O., Brice, P., Van Der Maazen, R., Re, A., Edeline, V., Fermé, C., Van Imhoff, G., Merli, F., Bouabdallah, R., Sebban, C., Specht, L., Stamatoullas, A., Delarue, R., Fiaccadori, V. & 6 others, , 1 Jun 2017, In: Journal of Clinical Oncology. 35, 16, p. 1786-1796 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human papillomavirus and oropharyngeal cancer in Greenland in 1994-2010
Avnstorp, M. B., Jensen, Ramon Gordon, Garnæs, E., Therkildsen, M. H., Norrild, B., Specht, Lena, von Buchwald, Christian & Homøe, Preben, 2013, In: International Journal of Circumpolar Health. 72, p. 22386Research output: Contribution to journal › Journal article › Research › peer-review
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Feasibility of breathing-adapted PET/CT imaging for radiation therapy of Hodgkin lymphoma
Aznar, M. C., Andersen, F., Berthelsen, A. K., Josipovic, M., Klausen, T. L., Jakobsen, A. L., Olsen, M., Petersen, P. M. & Specht, Lena, 2011, In: Cancer Imaging. 11, p. S117Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of dose to cardiac structures during breast irradiation
Aznar, M. C., Korreman, S., Pedersen, A. N., Persson, Gitte F., Josipovic, M. & Specht, Lena, 1 Aug 2011, In: British Journal of Radiology. 84, 1004, p. 743-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Minimizing Late Effects for Patients With Mediastinal Hodgkin Lymphoma: Deep Inspiration Breath-Hold, IMRT, or Both?
Aznar, M. C., Maraldo, M. V., Schut, D. A., Lundemann, M., Brodin, N. P., Vogelius, Ivan R. , Berthelsen, A. K., Specht, Lena & Petersen, P. M., 1 May 2015, In: International Journal of Radiation Oncology, Biology, Physics. 92, 1, p. 169-174Research output: Contribution to journal › Journal article › Research › peer-review
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Interobserver delineation uncertainty in involved-node radiation therapy (INRT) for early-stage Hodgkin lymphoma: on behalf of the Radiotherapy Committee of the EORTC lymphoma group
Aznar, M. C., Girinsky, T., Berthelsen, A. K., Aleman, B., Beijert, M., Hutchings, M., Lievens, Y., Meijnders, P., Petersen, P. M., Schut, D., Maraldo, M. V., van der Maazen, R. & Specht, Lena, 20 Jan 2017, In: Acta Oncologica. 56, 4, p. 608-613Research output: Contribution to journal › Journal article › Research › peer-review
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Use of Radiation in Extramedullary Leukemia/Chloroma: Guidelines From the International Lymphoma Radiation Oncology Group
Bakst, R. L., Dabaja, B. S., Specht, Lena & Yahalom, J., 2018, In: International Journal of Radiation Oncology, Biology, Physics. 102, 2, p. 314-319 6 p.Research output: Contribution to journal › Review › Research › peer-review
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Phase I/II clinical and pharmacokinetic study evaluating a fully human monoclonal antibody against EGFr (HuMax-EGFr) in patients with advanced squamous cell carcinoma of the head and neck
Bastholt, L., Specht, Lena, Jensen, K., Brun, E., Loft, A., Petersen, J., Kastberg, H. & Eriksen, J. G., 2007, In: Radiotherapy & Oncology. 85, 1, p. 24-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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OC-008 Incidence of malignant disease outside the head and neck region in head and neck cancer
Bernsdorf, M., Loft, A., Berthelsen, A., Specht, Lena, Kjems, J., Gothelf, A., Kristensen, C. & Friborg, J., 2017, In: Radiotherapy and Oncology. 122, Suppl 1, p. 7-8Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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What's new in target volume definition for radiologists in ICRU Report 71? How can the ICRU volume definitions be integrated in clinical practice?
Berthelsen, A. K., Dobbs, J., Kjellén, E., Landberg, T., Möller, T. R., Nilsson, P., Specht, Lena, Wambersie, A., Berthelsen, A. K., Dobbs, J., Kjellén, E., Landberg, T., Möller, T. R., Nilsson, P., Specht, Lena & Wambersie, A., 1 Jan 2007, In: Cancer Imaging. 7, p. 104-16 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of SPECT-CT in the lymphoscintigraphic identification of sentinel nodes in patients with oral cancer
Bilde, A., von Buchwald, Christian, Mortensen, Jann, Marving, J., Hamilton Therkildsen, M., Kirkegaard, J., Charabi, Birgitte Wittenborg & Specht, Lena, 2006, In: Acta Oto-Laryngologica. 126, 10, p. 1096-103 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Need for intensive histopathologic analysis to determine lymph node metastases when using sentinel node biopsy in oral cancer
Bilde, A., von Buchwald, Christian, Therkildsen, M. H., Mortensen, Jann, Kirkegaard, J., Charabi, Birgitte Wittenborg, Specht, Lena, Bilde, A., von Buchwald, C., Therkildsen, M. H., Mortensen, Jann, Kirkegaard, J., Charabi, Birgitte Wittenborg & Specht, Lena, 1 Mar 2008, In: Laryngoscope. 118, 3, p. 408-14 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Danish national guidelines for treatment of oral squamous cell carcinoma
Bilde, A., von Buchwald, Christian, Johansen, J., Bastholt, L., Sørensen, J. A. H. M., Marker, P., Krogdahl, A., Hansen, H. S., Specht, Lena, Kirkegaard, J., Andersen, E., Bentzen, J., Hjort-Sørensen, C., Andersen, L. J., Nielsen, B. A., Bundgaard, T., Overgaard, M., Grau, C. & Danish Society for Head and Neck Oncology, D. S. F. H. A. N. O., 2006, In: Acta Oncologica. 45, 3, p. 294-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stage I-II nodular lymphocyte-predominant Hodgkin lymphoma: A multi-institutional study of adult patients by ILROG
Binkley, M. S., Shahzad Rauf, M., Milgrom, S. A., Pinnix, C. C., Tsang, R., Dickinson, M., Ng, A. K., Roberts, K. B., Gao, S., Balogh, A., Ricardi, U., Levis, M., Casulo, C., Stolten, M., Specht, L., Plastaras, J. P., Wright, C., Kelsey, C. R., Brady, J. L., George Mikhaeel, N. & 17 others, , 2020, In: Blood. 135, 26, p. 2365-2374 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nimorazole may increase the effect of phenprocoumon
Bjarnason, N. H., Specht, Lena & Dalhoff, K., 2004, In: Radiotherapy & Oncology. 74, 3, p. 345Research output: Contribution to journal › Journal article › Research › peer-review
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The nimorazole regimen in patients with head and neck cancer can increase the effect of vitamin K antagonists
Bjarnason, N. H., Christiansen, M., Specht, Lena, Bjarnason, N. H., Christiansen, M. & Specht, Lena, 1 Jan 2008, In: Acta Oncologica. 47, 1, p. 150-1 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy
Bjerre, T., Hansen, M. F., Aznar, M. C., Munck af Rosenschöld, P. M., Specht, Lena & Larsen, R., 2012, In: International Symposium on Biomedical Imaging. Proceedings. p. 1224-27Research output: Contribution to journal › Journal article › Research › peer-review
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Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes
Bjerre, T., Crijns, S., Munck af Rosenschöld, P. M., Aznar, M. C., Specht, Lena, Larsen, R. & Keall, P., 21 Jul 2013, In: Physics in Medicin and biology. 58, 14, p. 4943-4950Research output: Contribution to journal › Journal article › Research › peer-review
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Chemotherapy alone versus chemotherapy plus radiotherapy for adults with early stage Hodgkin lymphoma (Review)
Blank, O., von Tresckow, B., Monsef, I., Specht, Lena, Engert, A. & Skoetz, N., 2017, In: Cochrane Database of Systematic Reviews. 4, 139 p., CD007110.Research output: Contribution to journal › Review › Research › peer-review
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Blodsygdomme.
Borregaard, N., Andersen, M. K., Berthelsen, A. K., Bjerrum, O. W., Brown, P. D. N., Geisler, C., Gimsing, P., Hansen, M., Jurlander, J., Kjeldsen, L., Loft, A., Nielsen, O. J., Ralfkiær, E., Sengeløv, H. & Specht, Lena, 2009, Medicinsk Kompendium. 17. ed. København: Nyt Nordisk Forlag Arnold Busck, p. 1762-1887Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Life years lost-comparing potentially fatal late complications after radiotherapy for pediatric medulloblastoma on a common scale
Brodin, N. P., Vogelius, I. R., Maraldo, M. V., Munck af Rosenschöld, P. M., Aznar, M. C., Berthelsen, A. K., Nilsson, P., Bjork-Eriksson, T., Specht, Lena & Bentzen, S. M., Nov 2012, In: Cancer. 118, 21, p. 5432-5440 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Optimizing the radiation therapy dose prescription for pediatric medulloblastoma: Minimizing the life years lost attributable to failure to control the disease and late complication risk
Brodin, N. P., Vogelius, Ivan R. , Bjork-Eriksson, T., af Rosenschold, P. M., Maraldo, M. V., Aznar, M. C., Specht, Lena & Bentzen, S. M., 1 Apr 2014, In: Acta Oncologica. 53, 4, p. 462-470Research output: Contribution to journal › Journal article › Research › peer-review
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Interactive Decision-Support Tool for Risk-Based Radiation Therapy Plan Comparison for Hodgkin Lymphoma
Brodin, N. P., Maraldo, M. V., Aznar, M. C., Vogelius, Ivan R. , Petersen, P. M., Bentzen, S. M. & Specht, Lena, 1 Feb 2014, In: International Journal of Radiation Oncology, Biology, Physics. 88, 2, p. 433-445Research output: Contribution to journal › Journal article › Research › peer-review
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Continuing rise in oropharyngeal cancer in a high HPV prevalence area: A Danish population-based study from 2011 to 2014
Carlander, A. F., Larsen, C. G., Jensen, D. H., Garnaes, E., Kiss, K., Andersen, L., Olsen, C. H., Franzmann, M., Høgdall, Estrid Vilma Solyom, Kjær, Susanne Krüger, Norrild, B., Specht, Lena, Andersen, E., Hansen, T. V. O., Nielsen, Finn Cilius & von Buchwald, Christian, Jan 2017, In: European Journal of Cancer. 70, p. 75-82Research output: Contribution to journal › Journal article › Research › peer-review
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Revised response criteria for malignant lymphoma
Cheson, B. D., Pfistner, B., Juweid, M. E., Gascoyne, R. D., Specht, L., Horning, S. J., Coiffier, B., Fisher, R. I., Hagenbeek, A., Zucca, E., Rosen, S. T., Stroobants, S., Lister, T. A., Hoppe, R. T., Dreyling, M., Tobinai, K., Vose, J. M., Connors, J. M., Federico, M., Diehl, V. & 1 others, , 10 Feb 2007, In: Journal of Clinical Oncology. 25, 5, p. 579-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The prevalence of occult metastases in nonsentinel lymph nodes after step-serial sectioning and immunohistochemistry in cN0 oral squamous cell carcinoma
Christensen, A., Bilde, A., Therkildsen, M. H., Mortensen, Jann, Charabi, Birgitte Wittenborg, Kirkegaard, J., Specht, Lena & Buchwald, C. V., 1 Feb 2011, In: Laryngoscope. 121, 2, p. 294-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ten-year retrospective study of head and neck carcinoma in situ: incidence, treatment, and clinical outcome
Christensen, Anders, Kristensen, E., Therkildsen, M. H., Specht, Lena, Reibel, Jesper & Homøe, Preben, 2013, In: Oral and Maxillofacial Surgery. 116, 2, p. 174-178 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Role of Radiation Therapy in Patients With Relapsed or Refractory Hodgkin Lymphoma: Guidelines From the International Lymphoma Radiation Oncology Group
Constine, L. S., Yahalom, J., Ng, A. K., Hodgson, D. C., Wirth, A., Milgrom, S. A., Mikhaeel, N. G., Eich, H. T., Illidge, T., Ricardi, U., Dieckmann, K., Moskowitz, C. H., Advani, R., Mauch, P. M., Specht, Lena & Hoppe, R. T., 2018, In: International Journal of Radiation Oncology, Biology, Physics. 100, 5, p. 1100-1118Research output: Contribution to journal › Review › Research › peer-review
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Early-stage mantle cell lymphoma: a retrospective analysis from the International Lymphoma Radiation Oncology Group (ILROG)
Dabaja, B. S., Zelenetz, A. D., Ng, A. K., Tsang, R. W., Qi, S., Allen, P. K., Hodgson, D., Ricardi, U., Hoppe, R. T., Advani, R., Mauch, P. M., Constine, L. S., Specht, L., Li, Y., Terezakis, S. A., Wirth, A., Reinartz, G., Eich, H. T., Aleman, B. M. P., Barr, P. & 1 others, , 2017, In: Annals of Oncology. 28, 9, p. 2185-2190Research output: Contribution to journal › Journal article › Research › peer-review
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Lymphoblastic Lymphoma: Guidelines From the International Lymphoma Radiation Oncology Group (ILROG)
Dabaja, B. S., Specht, Lena & Yahalom, J., 2018, In: International Journal of Radiation Oncology, Biology, Physics. 102, 3, p. 508-514 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Making Every Single Gray Count: Involved Site Radiation Therapy Delineation Guidelines for Hematological Malignancies
Dabaja, B. S., Ng, A. K., Terezakis, S. A., Plastaras, J. P., Yunes, M., Wilson, L. D., Specht, Lena & Yahalom, J., 2020, In: International Journal of Radiation Oncology Biology Physics. 106, 2, p. 279-281 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Proton therapy for adults with mediastinal lymphomas: the International Lymphoma Radiation Oncology Group guidelines
Dabaja, B. S., Hoppe, B. S., Plastaras, J. P., Newhauser, W., Rosolova, K., Flampouri, S., Mohan, R., Mikhaeel, N. G., Kirova, Y., Specht, Lena & Yahalom, J., 2018, In: Blood. 132, 16, p. 1635-1646 12 p.Research output: Contribution to journal › Review › Research › peer-review
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ILROG Lymphoma Mini-Atlas Part II, Hodgkin Lymphoma
Dabaja, B. S., Ng, A. K., Terezakis, S. A., Plastaras, J. P., Yunes, M., Wilson, L. D., Yang, J., Gunther, J. R., Specht, Lena & Yahalom, J., 2020, In: International Journal of Radiation Oncology Biology Physics. 108, 4, p. 977-978Research output: Contribution to journal › Editorial › Research › peer-review
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Feasibility of a novel liquid fiducial marker for use in image guided radiotherapy of oesophageal cancer
De Blanck, S. R., Scherman-Rydhog, J., Siemsen, Mette, Christensen, M., Baeksgaard, L., Jolck, R. I., Specht, Lena, Andresen, T. L. & Persson, Gitte F., 9 Jul 2018, In: British Journal of Radiology. 91, 1092, 5 p., 20180236.Research output: Contribution to journal › Journal article › Research › peer-review
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PET for radiotherapy planning
Dejanovic, D., Specht, Lena, Munk, O. L., Christensen, C. B., Berthelsen, A. K., Law, Ian & Loft, A., 2022, Nuclear Medicine and Molecular Imaging: Volume 1-4. Elsevier, Vol. 3. p. 774-792 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Response Evaluation Following Radiation Therapy With 18F-FDG PET/CT: Common Variants of Radiation-Induced Changes and Potential Pitfalls
Dejanovic, D., Specht, Lena, Czyzewska, D., Kiil Berthelsen, A. & Loft, A., 2022, In: Seminars in Nuclear Medicine. 52, 6, p. 681-706 26 p.Research output: Contribution to journal › Review › Research › peer-review
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Recurrences after intensity modulated radiotherapy for head and neck squamous cell carcinoma more likely to originate from regions with high baseline [18F]-FDG uptake
Due, A. K., Vogelius, Ivan R. , Aznar, M. C., Bentzen, S. M., Berthelsen, A. K., Korreman, S. S., Loft, A., Kristensen, C. A. & Specht, Lena, 1 Jun 2014, In: Radiotherapy & Oncology. 111, 3, p. 360-365Research output: Contribution to journal › Journal article › Research › peer-review
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Methodologies for localizing loco-regional hypopharyngeal carcinoma recurrences in relation to FDG-PET positive and clinical radiation therapy target volumes
Due, A. K., Korreman, S. S., Bentzen, S., Tomé, W., Bender, E., Aznar, M. C., Vogelius, I., Berthelsen, A. K., Kristensen, C. A., Specht, Lena & Bentzen, S., 1 Oct 2010, In: Acta Oncologica. 49, 7, p. 984-90 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PET/CT surveillance in patients with Hodgkin lymphoma in first remission is associated with low positive predictive value and high costs
El-Galaly, T. C., Mylam, K. J., Brown, P., Specht, Lena, Christiansen, I., Munksgaard, L., Johnsen, H. E., Loft, A., Bukh, A., Iyer, V. V., Lerberg Nielsen, A., Hutchings, M. & Loft, A., 2012, In: Haematologica. 2012;97(6):931-6Research output: Contribution to journal › Journal article › Research › peer-review
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Routine Bone Marrow Biopsy Has Little or No Therapeutic Consequence for Positron Emission Tomography/Computed Tomography-Staged Treatment-Naive Patients With Hodgkin Lymphoma
El-Galaly, T. C., d'Amore, F., Mylam, K. J., de Nully Brown, P., Bøgsted, M., Bukh, A., Specht, Lena, Loft, A., Iyer, V. V., Hjorthaug, K., Nielsen, A. L., Christiansen, I., Madsen, C. Ø., Johnsen, H. E. & Hutchings, M., 2012, In: Journal of Clinical Oncology. 30, 36, p. 4508-14Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ultrasonic mirror image from ruthenium plaque facilitates calculation of uveal melanoma treatment dose
Espensen, C. A., Jensen, P. K., Fog, L. S., Appelt, A. L., Klemp, Kristian, Fledelius, H. C., Specht, Lena & Kiilgaard, Jens Folke, Sep 2017, In: British Journal of Ophthalmology. 101, 9, p. 1206-1210 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A step and shoot intensity modulated technique for total body irradiation
Fog, L. S., Hansen, V. N., Kjær-kristoffersen, F., Berlon, T. E., Petersen, P. M., Mandeville, H. & Specht, Lena, 2019, In: Technical Innovations & Patient Support in Radiation Oncology. 10, p. 1-7Research output: Contribution to journal › Journal article › Research › peer-review
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Brentuximab Vedotin Plus AVD for First-Line Treatment of Early-Stage Unfavorable Hodgkin Lymphoma (BREACH): A Multicenter, Open-Label, Randomized, Phase II Trial
Fornecker, L. M., Lazarovici, J., Aurer, I., Casasnovas, R. O., Gac, A. C., Bonnet, C., Bouabdallah, K., Feugier, P., Specht, L., Molina, L., Touati, M., Borel, C., Stamatoullas, A., Nicolas-Virelizier, E., Pascal, L., Lugtenburg, P., Di Renzo, N., Vander Borght, T., Traverse-Glehen, A., Dartigues, P. & 5 others, , 2023, In: Journal of Clinical Oncology. 41, 2, p. 327-335 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Does hyperbaric oxygen treatment have the potential to increase salivary flow rate and reduce xerostomia in previously irradiated head and neck cancer patients? A pilot study
Forner, L., Hansen, O. H., von Brockdorff, A. S., Specht, Lena, Andersen, E., Jansen, E. C., Hillerup, S., Nauntofte, B. & Jensen, S. B., 1 Jun 2011, In: Oral Oncology. 47, 6, p. 546-551 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperbaric oxygen treatment of mandibular osteoradionecrosis: Combined data from the two randomized clinical trials DAHANCA-21 and NWHHT2009-1
Forner, L. E., Dieleman, F. J., Shaw, R. J., Kanatas, A., Butterworth, C. J., Kjeller, G., Alsner, J., Overgaard, J., Hillerup, S., Hyldegaard, Ole, Arnell, P., von Buchwald, Christian, Kaanders, J. H. A. M., Smeele, L. E., Specht, Lena, Johansen, J., Witjes, M. J. H., Merkx, M. A. W. & Jansen, E. C., Jan 2022, In: Radiotherapy and Oncology. 166, p. 137-144 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Second malignancy risk associated with treatment of Hodgkin's lymphoma: meta-analysis of the randomised trials
Franklin, J., Pluetschow, A., Paus, M., Specht, L., Anselmo, A-P., Aviles, A., Biti, G., Bogatyreva, T., Bonadonna, G., Brillant, C., Cavalieri, E., Diehl, V., Eghbali, H., Fermé, C., Henry-Amar, M., Hoppe, R., Howard, S., Meyer, R., Niedzwiecki, D., Pavlovsky, S. & 8 others, , 2006, In: Annals of Oncology. 17, 12, p. 1749-60 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemotherapy, radiotherapy and combined modality for Hodgkin's disease, with emphasis on second cancer risk
Franklin, J. G., Paus, M. D., Pluetschow, A., Specht, Lena, Franklin, J. G., Paus, M. D., Pluetschow, A. & Specht, Lena, 1 Jan 2005, In: Cochrane Database of Systematic Reviews. 4, p. CD003187Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody response to pneumococcal vaccine in patients with early stage Hodgkin's disease
Frederiksen, B., Specht, Lena, Henrichsen, J., Pedersen, F. K. & Pedersen-Bjergaard, J., 1989, In: European Journal of Haematology. 43, 1, p. 45-49 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early interim 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography is prognostically superior to international prognostic score in advanced-stage Hodgkin's lymphoma: a report from a joint Italian-Danish study
Gallamini, A., Hutchings, M., Rigacci, L., Specht, L., Merli, F., Hansen, M., Patti, C., Loft, A., Di Raimondo, F., D'Amore, F., Biggi, A., Vitolo, U., Stelitano, C., Sancetta, R., Trentin, L., Luminari, S., Iannitto, E., Viviani, S., Pierri, I., Levis, A. & 20 others, , 20 Aug 2007, In: Journal of Clinical Oncology. 25, 24, p. 3746-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increasing incidence of base of tongue cancers from 2000 to 2010 due to HPV: the largest demographic study of 210 Danish patients
Garnaes, E., Kiss, K., Andersen, L., Therkildsen, M. H., Franzmann, M. B., Filtenborg-Barnkob, B., Hoegdall, E., Lajer, C. B., Andersen, E., Specht, Lena, Joenson, L., Frederiksen, K., Friis-Hansen, Lennart Jan, Nielsen, Finn Cilius, Kjær, Susanne Krüger, Norrild, B. & von Buchwald, Christian, 30 Jun 2015, In: B J C. 113, 1, p. 131-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A high and increasing HPV prevalence in tonsillar cancers in Eastern Denmark, 2000-2010: The largest registry-based study to date
Garnaes, E., Kiss, K., Andersen, L., Therkildsen, M. H., Franzmann, M. B., Filtenborg-Barnkob, B., Høgdall, Estrid Vilma Solyom, Krenk, L., Josiassen, M., Lajer, C. B., Specht, Lena, Frederiksen, K., Friis-Hansen, Lennart Jan, Nielsen, Finn Cilius, Kjær, Susanne Krüger, Norrild, B. & von Buchwald, Christian, 1 May 2015, In: International journal of cancer. Journal international du cancer. 136, 9, p. 2196-203 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Double positivity for HPV DNA/p16 in tonsillar and base of tongue cancer improves prognostication: Insights from a large population-based study
Garnaes, E., Frederiksen, K., Kiss, K., Andersen, L., Therkildsen, M. H., Franzmann, M. B., Specht, Lena, Andersen, E., Norrild, B., Kjær, Susanne Krüger & von Buchwald, Christian, 1 Dec 2016, In: International Journal of Cancer. 139, 11, p. 2598-2605 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Target definitions for Hodgkin lymphoma: the involved node radiation field concept
Girinsky, T., Ghalibafian, M. & Specht, Lena, 2011, Radiotherapy for Hodgkin lymphoma. Specht, L. & Yahalom, J. (eds.). Berlin: Springer, p. 91-122 32 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Involved-node radiotherapy (INRT) in patients with early Hodgkin lymphoma: concepts and guidelines
Girinsky, T., van der Maazen, R., Specht, Lena, Aleman, B., Poortmans, P., Lievens, Y., Meijnders, P., Ghalibafian, M., Meerwaldt, J. & Noordijk, E., 2006, In: Radiotherapy & Oncology. 79, 3, p. 270-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The conundrum of Hodgkin lymphoma nodes: to be or not to be included in the involved node radiation fields. The EORTC-GELA lymphoma group guidelines
Girinsky, T., Specht, L., Ghalibafian, M., Edeline, V., Bonniaud, G., Van Der Maazen, R., Aleman, B., Paumier, A., Meijnders, P., Lievens, Y., Noordijk, E., Poortmans, P., EORTC-GELA Lymphoma Group, Girinsky, T., Specht, L., Ghalibafian, M., Edeline, V., Bonniaud, G., Van Der Maazen, R., Aleman, B. & 6 others, , 1 Aug 2008, In: Radiotherapy & Oncology. 88, 2, p. 202-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Centraliseret efterkontrol af patienter behandlet for hoved-halskraeft
Grau, C., Specht, Lena, Hansen, H. S., Overgaard, M. & Overgaard, J., 17 Feb 1997, In: Ugeskrift for Laeger. 159, 8, p. 1104-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
[Centralized follow-up of patients treated for head and neck cancer]
Grau, C., Specht, Lena, Hansen, H. S., Overgaard, M. & Overgaard, J., 1997, In: Ugeskrift for læger. 159, 8, p. 1104-1108 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Time to Treatment Initiation in Patients with Human Papillomavirus-positive and -negative Oropharyngeal Squamous Cell Carcinoma
Grønhøj, C., Jensen, D., Dehlendorff, C., Nørregaard, C., Andersen, E., Specht, Lena, Charabi, Birgitte Wittenborg & von Buchwald, Christian, 2018, In: Clinical Oncology. 30, 6, p. 375-381 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-in-man mesenchymal stem cells for radiation-induced xerostomia (MESRIX): study protocol for a randomized controlled trial.
Grønhøj, C., Jensen, D. H., Glovinski, P. V., mpw981, M., Jensen, A. B., Oliveri, R. S., Specht, Lena, Thomsen, C., Darkner, Sune, Kiss, K., Fischer-Nielsen, A. & von Buchwald, Christian, 2017, In: Trials. 18, 1, 10 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deep sequencing of human papillomavirus positive loco-regionally advanced oropharyngeal squamous cell carcinomas reveals novel mutational signature
Grønhøj, C., Jensen, D. H., Agander, T., Kiss, K., Høgdall, Estrid Vilma Solyom, Specht, Lena, Bagger, F. O., Nielsen, Finn Cilius & von Buchwald, Christian, 2018, In: BMC Cancer. 18, 1, p. 1-10 10 p., 640.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safety and Efficacy of Mesenchymal Stem Cells for Radiation-Induced Xerostomia: A Randomized, Placebo-Controlled Phase 1/2 Trial (MESRIX)
Grønhøj, C., Jensen, D. H., Vester-Glowinski, Peter Viktor, Jensen, S. B., Bardow, A., Oliveri, R. S., Fog, L. M., Specht, Lena, Thomsen, C., Darkner, Sune, Jensen, M., Müller, V., Kiss, K., Agander, T., Andersen, E., Fischer-Nielsen, A. & von Buchwald, Christian, 1 Jul 2018, In: International Journal of Radiation Oncology, Biology, Physics. 101, 3, p. 581-592 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Geometric distortions of diffusion weighted imaging of the head/neck in combined PET/MR: optimization of image acquisition and post-processing correction for oncology applications
Hansen, Adam Espe, Rasmussen, J., Johannesen, H. H., Engberg, A. M., Andersen, F. L., Specht, Lena, Kjær, Andreas, Højgaard, Liselotte, Beyer, T. & Fischer, Barbara Malene Bjerregaard, Jul 2014, In: E J N M M I Physics. 1, Suppl 1, 2 p., A76.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
MiR-21 expression in the tumor stroma of oral squamous cell carcinoma: an independent biomarker of disease free survival
Hedbäck, N., Jensen, D. H., Specht, Lena, Fiehn, A. K., Therkildsen, M. H., Friis-Hansen, Lennart Jan, Dabelsteen, Erik & von Buchwald, Christian, 2014, In: PLOS ONE. 9, 4, p. 1-11 11 p., e95193.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemotherapy alone versus chemotherapy plus radiotherapy for early stage Hodgkin lymphoma
Herbst, C., Rehan, F. A., Skoetz, N., Bohlius, J., Brillant, C., Schulz, H., Monsef, I., Specht, Lena & Engert, A., 1 Jan 2011, In: Cochrane Database of Systematic Reviews. 2, p. CD007110Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined modality treatment improves tumor control and overall survival in patients with early stage Hodgkin's lymphoma: a systematic review
Herbst, C., Rehan, F. A., Brillant, C., Bohlius, J., Skoetz, N., Schulz, H., Monsef, I., Specht, Lena, Engert, A., Herbst, C., Rehan, F. A., Brillant, C., Bohlius, J., Skoetz, N., Schulz, H., Monsef, I., Specht, Lena & Engert, A., 1 Mar 2010, In: Haematologica. 95, 3, p. 494-500 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Iatrogenic cerebral radiation necrosis
Hilton, C. M. H., Specht, Lena, Lund, Eva Løbner, Martens, P. C., Schmidt, G. & Krarup, L. H., 2021, In: Practical Neurology. 21, 5, p. 427-430 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Total Body Irradiation in Haematopoietic Stem Cell Transplantation for Paediatric Acute Lymphoblastic Leukaemia: Review of the Literature and Future Directions
Hoeben, B. A. W., Wong, J. Y. C., Fog, L. S., Losert, C., Filippi, A. R., Bentzen, S. M., Balduzzi, A. & Specht, Lena, 2021, In: Frontiers in Pediatrics. 9, 28 p., 774348.Research output: Contribution to journal › Review › Research › peer-review
- Published
Does transfusion improve the outcome for HNSCC patients treated with radiotherapy? - Results from the randomized DAHANCA 5 and 7 trials
Hoff, C. M., Lassen, P., Eriksen, J. G., Hansen, H. S., Specht, Lena, Overgaard, M., Grau, C., Johansen, J., Bentzen, J., Andersen, L., Evensen, J. F. & Overgaard, J., 1 Oct 2011, In: Acta Oncologica. 50, 7, p. 1006-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in radiotherapy delivery and outcome due to contouring variation
Hollensen, C., Persson, Gitte F., Højgaard, Liselotte, Specht, Lena & Larsen, R., 2013, Clinical Image-Based Procedures: From Planning to Intervention - International Workshop, CLIP 2012, Held in Conjunction with MICCAI 2012, Revised Selected Papers. Springer Verlag, p. 122-129 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol. 7761 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Proton therapy for Hodgkin lymphoma
Hoppe, B., Slopsema, R. & Specht, Lena, 2011, Radiotherapy for Hodgkin lymphoma. Specht, L. & Yahalom, J. (eds.). Berlin: Springer, p. 197-203 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Survival analysis of patients with clinical stages I or II Hodgkin's disease who have relapsed after initial treatment with radiotherapy alone
Horwich, A., Specht, Lena & Ashley, S., 1997, In: European Journal of Cancer. 33, 6, p. 848-853 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Volume of abnormal tumour tissue on FDG-PET - a predictor of progression-free survival in Hodgkin lymphoma?
Hutchings, M., Berthelsen, A. K., Jakobsen, A. L. & Specht, Lena, 2005Research output: Other contribution › Research
- Published
FDG-PET in the clinical management of Hodgkin lymphoma
Hutchings, M., Eigtved, A. I. & Specht, Lena, 2004, In: Critical Reviews in Oncology/Hematology. 52, 1, p. 19-32 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FDG-PET after two cycles of chemotherapy predicts treatment failure and progression-free survival in Hodgkin lymphoma
Hutchings, M., Loft, A., Hansen, M., Pedersen, L. M., Buhl, T., Jurlander, J., Buus, S., Keiding, S., D'Amore, F., Boesen, A., Berthelsen, A. K. & Specht, Lena, 2005, In: Blood. 107, 1, p. 52-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Different histopathological subtypes of Hodgkin lymphoma show significantly different levels of FDG uptake
Hutchings, M., Loft, A., Hansen, M., Ralfkiaer, E., Specht, Lena, Hutchings, M., Jakobsen, A. L., Hansen, M., Ralfkiaer, E. & Specht, Lena, 1 Sep 2006, In: Hematological Oncology. 24, 3, p. 146-50 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical impact of FDG-PET/CT in the planning of radiotherapy for early-stage Hodgkin lymphoma
Hutchings, M., Loft, A., Hansen, M., Berthelsen, A. K., Specht, Lena, Hutchings, M., Jakobsen, A. L., Hansen, M., Berthelsen, A. K. & Specht, Lena, 1 Mar 2007, In: European Journal of Haematology. 78, 3, p. 206-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vivo Treatment Sensitivity Testing With Positron Emission Tomography/Computed Tomography After One Cycle of Chemotherapy for Hodgkin Lymphoma
Hutchings, M., Kostakoglu, L., Zaucha, J. M., Malkowski, B., Biggi, A., Danielewicz, I., Loft, A., Specht, Lena, Lamonica, D., Czuczman, M. S., Nanni, C., Zinzani, P. L., Diehl, L., Stern, R. & Coleman, M., 1 Sep 2014, In: Journal of Clinical Oncology. 32, 25, p. 2705-2711 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PET/CT in the management of haematological malignancies
Hutchings, M., Specht, Lena, Hutchings, M. & Specht, Lena, 1 May 2008, In: European Journal of Haematology. Supplementum. 80, 5, p. 369-80 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Position emission tomography with or without computed tomography in the primary staging of Hodgkin's lymphoma
Hutchings, M., Loft, A., Hansen, M., Pedersen, L. M., Berthelsen, A. K., Keiding, S., D'Amore, F., Boesen, A., Roemer, L. & Specht, Lena, 2006, In: Haematologica. 91, 4, p. 482-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the relation between improved loco-regional control and disease-free survival in head-and-neck cancer
Håkansson, K., Rasmussen, J. H., Bentzen, S. M., Friborg, Jeppe Tang, Specht, Lena & Vogelius, Ivan R. , 2019, In: Acta Oncologica. 58, 3, p. 390-392 3 p.Research output: Contribution to journal › Comment/debate › Research
- Published
A comparison of loco-regional relapse pattern in HPV positive vs negative oropharyngeal cancers following radiotherapy: relation to pretreatment FDG-PET and radiotherapy target volumes
Håkansson, K., Lindegaard, A. M., Bernsdorf, M., Gothelf, A., Kristensen, C. A., Specht, Lena, Friborg, Jeppe Tang & Vogelius, Ivan R. , 2023, In: Acta Oncologica. 62, 9, p. 1028-1035 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A failure-type specific risk prediction tool for selection of head-and-neck cancer patients for experimental treatments
Håkansson, K., Rasmussen, J. H., Rasmussen, G. B., Friborg, J., Gerds, Thomas Alexander, Fischer, Barbara Malene Bjerregaard, L. Andersen, F., M. Bentzen, S., Specht, Lena & Vogelius, Ivan R. , Nov 2017, In: Oral Oncology. 74, p. 77-82 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radiation dose-painting with protons vs. photons for head-and-neck cancer
Håkansson, K., Smulders, B., Specht, Lena, Zhu, M., Friborg, Jeppe Tang, Rasmussen, J. H., Bentzen, S. M. & Vogelius, I. R., 2020, In: Acta Oncologica. 59, 5, p. 525-533Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PET/CT in head and neck cancer
Højgaard, Liselotte & Specht, Lena, 2007, In: European Journal of Nuclear Medicine and Molecular Imaging. 34, 9, p. 1329-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modern Radiation Therapy for Nodal Non-Hodgkin Lymphoma—Target Definition and Dose Guidelines From the International Lymphoma Radiation Oncology Group
Illidge, T., Specht, Lena, Yahalom, J., Aleman, B., Berthelsen, A. K., Constine, L., Dabaja, B., Dharmarajan, K., Ng, A., Ricardi, U., Wirth, A. & International Lymphoma Radiation Oncology Group, I. L. R. O. G., 2014, In: International Journal of Radiation Oncology, Biology, Physics. 89, 1, p. 49-58 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lymphoma: advances in imaging and radiotherapy – introductory editorial
Illidge, T., Mikhaeel, N. G., Specht, Lena & Yahalom, J., 2021, In: British Journal of Radiology. 94, 1127, 2 p., 20219005.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Incidence and survival of hypopharyngeal cancer: a Danish Nation-Wide Study from 1980 to 2014
Jakobsen, K. K., Wingstrand, V. L., Jensen, J. S., Grønhøj, C., Jensen, D. H., Karnov, K., Agander, T. K., Specht, Lena & von Buchwald, Christian, 2019, In: Acta Oncologica. 58, 11, p. 1570-1576 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increasing incidence and survival of head and neck cancers in Denmark: a nation-wide study from 1980 to 2014
Jakobsen, K. K., Grønhøj, C., Jensen, D. H., Karnov, K. K. S., Agander, T. K., Specht, Lena & von Buchwald, Christian, 2018, In: Acta Oncologica. 57, 9, p. 1143-1151 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular profiling of tumour budding implicates TGFβ-mediated epithelial–mesenchymal transition as a therapeutic target in oral squamous cell carcinoma
Jensen, D. H., Dabelsteen, Erik, Specht, Lena, Fiehn, A. M., Therkildsen, M. H., Jønson, L., Vikesaa, J., Nielsen, Finn Cilius & von Buchwald, Christian, Aug 2015, In: Journal of Pathology. 236, 4, p. 505-516 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human papillomavirus in head and neck squamous cell carcinoma of unknown primary is a common event and a strong predictor of survival
Jensen, D. H., Hedback, N., Specht, Lena, Høgdall, E., Andersen, E., Therkildsen, M. H., Friis-Hansen, Lennart Jan, Norrild, B. & von Buchwald, Christian, 2014, In: PLOS ONE. 9, 11, p. 1-8 8 p., e110456.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mesenchymal stem cell therapy for salivary gland dysfunction and xerostomia: a systematic review of preclinical studies
Jensen, D. H., Oliveri, R. S., Trojahn-Kølle, S., Fischer-Nielsen, A., Specht, Lena, Jensen, A. B. & von Buchwald, Christian, 2014, In: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology. 117, 3, p. 335-342 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incidence and survival of oropharyngeal cancer in Denmark: a nation-wide, population-based study from 1980 to 2014
Jensen, J. S., Jensen, D. H., Grønhøj, C., Karnov, K. K. S., Nørregaard, C., Agander, T. K., Specht, Lena & von Buchwald, Christian, 2018, In: Acta Oncologica. 57, 2, p. 269-275Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early non-cancer mortality risk prediction after curative-intent radiotherapy or chemoradiotherapy for head and neck squamous cell carcinoma
Jensen, K. H., Vogelius, Ivan R. , Bernsdorf, M., Gothelf, A., Kristensen, C. A., Maare, C., Andersen, E., Specht, Lena & Friborg, Jeppe Tang, Jun 2022, In: Radiotherapy and Oncology. 171, p. 1-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Survival of head and neck cancer in Greenland
Jensen, R. G., Friborg, J., Rosborg, J., Specht, Lena, Brofeldt, S., Hamilton Therkildsen, M. & Homøe, Preben, 1 Sep 2010, In: International Journal of Circumpolar Health. 69, 4, p. 373-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correlation between HPV status at T and N sites of oropharyngeal squamous cell carcinomas
Josiassen, M. V., Charabi, Birgitte Wittenborg, Lajer, C. B., Garnaes, E., Hamilton Therkildsen, M., Norrild, B., Specht, Lena, Nielsen, Finn Cilius & von Buchwald, Christian, Dec 2017, In: Acta Oto-Laryngologica. 137, 12, p. 1260-1264 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 917341
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Immunohistochemical biomarkers and FDG uptake on PET/CT in head and neck squamous cell carcinoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
332
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First-in-man mesenchymal stem cells for radiation-induced xerostomia (MESRIX): study protocol for a randomized controlled trial.
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
188
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Deep inspiration breath-hold radiotherapy for lung cancer: impact on image quality and registration uncertainty in cone beam CT image guidance
Research output: Contribution to journal › Journal article › Research › peer-review
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