Benjamin Skov Kaas-Hansen
Assistant lecturer
Section of Biostatistics
Øster Farimagsgade 5 opg. B
1353 København K
- Published
Effects of restrictive fluid therapy on the time to resolution of hyperlactatemia in ICU patients with septic shock. A secondary post hoc analysis of the CLASSIC randomized trial
Ahlstedt, C., Sivapalan, P., Kriz, M., Jacobson, G., Sylvest Meyhoff, T., Kaas-Hansen, Benjamin Skov, Holm, M., Hollenberg, J., Nalos, M., Rooijackers, O., Møller, Morten Hylander, Cronhjort, M., Perner, Anders & Grip, J., 2024, In: Intensive Care Medicine. 50, 5, p. 678-686 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study
Burn, E., You, S. C., Sena, A. G., Kostka, K., Abedtash, H., Abrahão, M. T. F., Alberga, A., Alghoul, H., Alser, O., Alshammari, T. M., Aragon, M., Areia, C., Banda, J. M., Cho, J., Culhane, A. C., Davydov, A., DeFalco, F. J., Duarte-Salles, T., DuVall, S., Falconer, T. & 49 others, , 2020, In: Nature Communications. 11, 1, 11 p., 5009.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design considerations in clinical trials with adaptive stopping, arm-dropping and randomisation
Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, T., Schjorring, O., Andersen, L., Perner, Anders, Jensen, A. & Møller, M., 2022, p. S88-S89. 2 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Heterogeneity of treatment effect of prophylactic pantoprazole in adult ICU patients: a post hoc analysis of the SUP-ICU trial
Granholm, A., Marker, S., Krag, M., Zampieri, F. G., Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, van der Horst, I. C. C., Lange, Theis, Wetterslev, J., Perner, Anders & Møller, Morten Hylander, 2020, In: Intensive Care Medicine. 46, p. 717–726 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient-important outcomes other than mortality in recent ICU trials: protocol for a scoping review
Granholm, A., Kaas-Hansen, Benjamin Skov, Kjaer, M. N., Anthon, C. T., Sivapalan, P., Schjørring, O. L., Andersen, L. W., Mathiesen, Ole, Strøm, T., Jensen, Aksel Karl Georg, Perner, Anders & Møller, Morten Hylander, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 7, p. 1002-1007 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of days alive without life support and similar count outcomes in randomised clinical trials – an overview and comparison of methodological choices and analysis methods
Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, Theis, Munch, M. W., Harhay, M. O., Zampieri, F. G., Perner, Anders, Møller, Morten Hylander & Jensen, Aksel Karl Georg, 2023, In: BMC Medical Research Methodology. 23, 1, 12 p., 139.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Empirical meropenem versus piperacillin/tazobactam for adult patients with sepsis (EMPRESS) trial: Protocol
Granholm, A., Munch, M. W., Meier, N., Sjövall, F., Helleberg, Marie, Hertz, Frederik Boëtius, Kaas-Hansen, Benjamin Skov, Thorsen-Meyer, H. C., Andersen, L. W., Rasmussen, B. S., Andersen, J. S., Albertsen, T. L., Kjær, M. B. N., Jensen, Aksel Karl Georg, Lange, Theis, Perner, Anders & Møller, Morten Hylander, 2024, (Accepted/In press) In: Acta Anaesthesiologica Scandinavica.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Effects of sceptical priors on the performance of adaptive clinical trials with binary outcomes
Granholm, A., Lange, Theis, Harhay, M. O., Perner, Anders, Møller, Morten Hylander & Kaas-Hansen, Benjamin Skov, 2024, (E-pub ahead of print) In: Pharmaceutical Statistics. 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Health-related quality of life and days alive without life support or out of hospital: protocol
Granholm, A., Schjørring, O. L., Jensen, Aksel Karl Georg, Kaas-Hansen, Benjamin Skov, Munch, M. W., Klitgaard, T. L., Crescioli, E., Kjaer, M. N., Strøm, T., Perner, Anders, Rasmussen, B. S. & Møller, Morten Hylander, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 2, p. 295-301 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneity of treatment effect of stress ulcer prophylaxis in ICU patients: A secondary analysis protocol
Granholm, A., Marker, S., Krag, M., Zampieri, F. G., Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, van der Horst, I. C. C., Lange, Theis, Wetterslev, J., Perner, Anders & Møller, Morten Hylander, 2019, In: Acta Anaesthesiologica Scandinavica. 63, 9, p. 1251-1256 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of duration of follow-up and lag in data collection on the performance of adaptive clinical trials
Granholm, A., Lange, Theis, Harhay, M. O., Jensen, Aksel Karl Georg, Perner, Anders, Møller, Morten Hylander & Kaas-Hansen, Benjamin Skov, 2023, In: Pharmaceutical Statistics. 23, 2, p. 138-150 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An overview of methodological considerations regarding adaptive stopping, arm dropping and randomisation in clinical trials
Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, Theis, Schjørring, O. L., Andersen, L. W., Perner, Anders, Jensen, Aksel Karl Georg & Møller, Morten Hylander, 2023, In: Journal of Clinical Epidemiology. 153, p. 45-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between days alive without life support/out of hospital and health-related quality of life
Granholm, A., Schjorring, O. L., Jensen, Aksel Karl Georg, Kaas-Hansen, Benjamin Skov, Munch, M. W., Klitgaard, T. L., Crescioli, E., Kjaer, M. N., Strom, T., Lange, Theis, Perner, Anders, Rasmussen, B. S. & Møller, Morten Hylander, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 6, p. 762-771 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient-Important Outcomes Other Than Mortality in Contemporary ICU Trials: A Scoping Review
Granholm, A., Anthon, C. T., Kjær, M. N., Maagaard, M., Kaas-Hansen, Benjamin Skov, Sivapalan, P., Schjørring, O. L., Andersen, L. W., Mathiesen, Ole, Strøm, T., Jensen, Aksel Karl Georg, Perner, Anders & Møller, Morten Hylander, 2022, In: Critical Care Medicine. 50, 10, p. e759-e771 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
adaptr: an R package for simulating and comparing adaptive clinical trials
Granholm, A., Jensen, Aksel Karl Georg, Lange, Theis & Kaas-Hansen, Benjamin Skov, 2022, In: Journal of Open Source Software. 7, 72, 1 p., 4284.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Different Original and Biosimilar TNF Inhibitors Similarly Reduce Joint Destruction in Rheumatoid Arthritis-A Network Meta-Analysis of 36 Randomized Controlled Trials
Graudal, N., Kaas-Hansen, Benjamin Skov, Guski, L., Hubeck-Graudal, T., Welton, N. J. & Jürgens, Gesche, 2019, In: International Journal of Molecular Sciences. 20, 18, 19 p., 4350.Research output: Contribution to journal › Review › Research › peer-review
- Published
Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients
Jimenez-Solem, E., Petersen, T. S., Hansen, C., Hansen, C., Lioma, C., Igel, C., Boomsma, W., Krause, O., Lorenzen, S., Selvan, R., Petersen, J., Nyeland, M. E., Ankarfeldt, M. Z., Virenfeldt, G. M., Winther-Jensen, M., Linneberg, A., Ghazi, M. M., Detlefsen, N., Lauritzen, A. D., Smith, A. G. & 15 others, , 2021, In: Scientific Reports. 11, 1, 12 p., 3246.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Routine Cytochrome P450 2D6 and 2C19 Genotyping on Antipsychotic Drug Persistence in Patients With Schizophrenia: A Randomized Clinical Trial
Jürgens, Gesche, Andersen, Stig Ejdrup, Rasmussen, H. B., Werge, Thomas, Jensen, H. D., Kaas-Hansen, Benjamin Skov & Nordentoft, Merete, 1 Dec 2020, In: JAMA Network Open. 3, 12, p. e2027909Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is the CYP2D6 Genotype Associated with Antipsychotic-Induced Weight Gain?
Jürgens, Gesche, Kaas-Hansen, Benjamin Skov, Nordentoft, Merete, Werge, Thomas & Andersen, Stig Ejdrup, Oct 2022, In: Journal of Personalized Medicine. 12, 10, 12 p., 1728.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eliciting drug safety signals from patient records: a language-agnostic approach
Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodriguez, C., Thorsen-Meyer, H., Gentile, S., Nielsen, A., Brunak, Søren, Jürgens, Gesche & Andersen, S., 2022, p. S15-S16. 2 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Causal inference for planning randomised critical care trials: protocol for a scoping review
Kaas-Hansen, Benjamin Skov, Granholm, A., Anthon, C. T., Kjær, M. N., Sivapalan, P., Maagaard, M., Schjørring, O. L., Fagerberg, S. K., Ellekjær, K. L., Mølgaard, J., Ekstrøm, Claus Thorn, Møller, Morten Hylander & Perner, Anders, Oct 2022, In: Acta Anaesthesiologica Scandinavica. 66, 10, p. 1274–1278 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Health-related quality of life trajectories in critical illness: Protocol for a Monte Carlo simulation study
Kaas-Hansen, Benjamin Skov, Kjaer, M. N., Møller, Morten Hylander, Jensen, Aksel Karl Georg, Larsen, M. E., Cuthbertson, B. H., Perner, Anders & Granholm, A., 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records
Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodríguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, In: Basic & clinical pharmacology & toxicology. 131, 4, p. 282-293 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identifying patients at high risk of inappropriate drug dosing in periods with renal dysfunction
Kaas-Hansen, Benjamin Skov, Rodriguez, C. L., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2021, medRxiv.Research output: Working paper › Preprint
- Published
Severe Violence in Eastern Jutland 2003-2014
Kaas-Hansen, Benjamin Skov & Hansen, O. I., 2016.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records
Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodrìguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, Authorea, (Authorea Preprints).Research output: Working paper › Preprint
- Published
Severe violence in Eastern Jutland 2003-2014: a pilot study [v1; not peer reviewed]: A pilot study [v1; not peer reviewed]
Kaas-Hansen, Benjamin Skov, 7 Nov 2015.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Real-world causal evidence for planned predictive enrichment in critical care trials: A scoping review
Kaas-Hansen, Benjamin Skov, Granholm, A., Sivapalan, P., Anthon, C. T., Schjørring, O. L., Maagaard, M., Kjaer, M. N., Mølgaard, J., Ellekjaer, K. L., Fagerberg, S. K., Lange, Theis, Møller, Morten Hylander & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 16-25 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Machine Learning to Identify Patients at Risk of Inappropriate Dosing for Renal Risk Medications: A Critical Comment on Kaas-Hansen et al [Response to Letter]
Kaas-Hansen, Benjamin Skov, Leal Rodríguez, C., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2022, In: Clinical Epidemiology. 14, p. 765-766 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Using Machine Learning to Identify Patients at High Risk of Inappropriate Drug Dosing in Periods with Renal Dysfunction
Kaas-Hansen, Benjamin Skov, Leal Rodríguez, C., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2022, In: Clinical Epidemiology. 14, p. 213-223 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacovigilant Machine Learning in Big Data?
Kaas-Hansen, Benjamin Skov, 2022Research output: Book/Report › Ph.D. thesis › Research
- Published
Exploratory pharmacovigilance with machine learning in big patient data: a focused scoping review
Kaas-Hansen, Benjamin Skov, Gentile, S., Caioli, A. & Andersen, Stig Ejdrup, 2023, In: Basic & clinical pharmacology & toxicology. 132, 3, p. 233-241 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study
Lane, J. C. E., Weaver, J., Kostka, K., Duarte-Salles, T., Abrahao, M. T. F., Alghoul, H., Alser, O., Alshammari, T. M., Biedermann, P., Banda, J. M., Burn, E., Casajust, P., Conover, M. M., Culhane, A. C., Davydov, A., DuVall, S. L., Dymshyts, D., Fernandez-Bertolin, S., Fišter, K., Hardin, J. & 31 others, , 2020, In: The Lancet Rheumatology. 2, 11, p. e698-e711 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk of depression, suicide and psychosis with hydroxychloroquine treatment for rheumatoid arthritis: a multinational network cohort study
Lane, J. C. E., Weaver, J., Kostka, K., Duarte-Salles, T., Abrahao, M. T. F., Alghoul, H., Alser, O., Alshammari, T. M., Areia, C., Biedermann, P., Banda, J. M., Burn, E., Casajust, P., Fister, K., Hardin, J., Hester, L., Hripcsak, G., Kaas-Hansen, B. S., Khosla, S., Kolovos, S. & 29 others, , 2021, In: Rheumatology. 60, 7, p. 3222–3234 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Platform trials: Platformsforsøg
Perner, A., Kjær, M. B. N., Thorsen-Meyer, H. C., Kaas-Hansen, B. S., Munch, M. W., Collet, M. O., Bruun, C. R., Jensen, A. K., Lange, T., Albertsen, T., Pedersen, C. D., Poulsen, L. M., Mathiesen, O., Brøchner, A. C., Strøm, T., Andersen, L. W., Christensen, S., Rasmussen, B. S., Schjørring, O. L., Maagaard, M. & 2 others, , 2023, In: Ugeskrift for Laeger. 185, 41, 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
- Published
Development of a dynamic prediction model for unplanned ICU admission and mortality in hospitalized patients
Placido, Davide, Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, Reguant, R. & Brunak, Søren, 2023, In: PLOS Digital Health. 2, 6, 18 p., e0000116.Research output: Contribution to journal › Journal article › Research › peer-review
Beyond access to medicines: Eliciting high-income country support for a new global health research and development paradigm
Regmi, S., Kaas-Hansen, Benjamin Skov & Iversen, J. H., 2013, In: Journal of Global Health. 3, 2, 6 p., 020303.Research output: Contribution to journal › Review › Research › peer-review
- Published
Implementation of the COVID-19 Vulnerability Index Across an International Network of Health Care Data Sets: Collaborative External Validation Study
Reps, J. M., Kim, C., Williams, R. D., Markus, A. F., Yang, C., Salles, T. D., Falconer, T., Jonnagaddala, J., Williams, A., Fernández-Bertolín, S., DuVall, S. L., Kostka, K., Rao, G., Shoaibi, A., Ostropolets, A., Spotnitz, M. E., Zhang, L., Casajust, P., Steyerberg, E. W., Nyberg, F. & 16 others, , 2021, In: J M I R Medical Informatics. 9, 4, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug interactions in hospital prescriptions in Denmark: Prevalence and associations with adverse outcomes
Rodríguez, C. L., Kaas-Hansen, Benjamin Skov, Eriksson, R., Biel, J. H., Belling, K. G., Andersen, Stig Ejdrup & Brunak, Søren, 2022, In: Pharmacoepidemiology and Drug Safety. 31, 6, p. 632-642 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restrictive versus standard IV fluid therapy in adult ICU patients with septic shock—Bayesian analyses of the CLASSIC trial
Sivapalan, P., Meyhoff, T. S., Hjortrup, P. B., Lange, Theis, Kaas-Hansen, Benjamin Skov, Kjær, M. B. N., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2024, In: Acta Anaesthesiologica Scandinavica. 68, 2, p. 236-246 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Effects of IV fluid restriction according to site-specific intensity of standard fluid treatment-protocol
Sivapalan, P., Kaas-Hansen, Benjamin Skov, Meyhoff, T. S., Hjortrup, P. B., Kjær, M. N., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2024, (E-pub ahead of print) In: Acta Anaesthesiologica Scandinavica. 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discrete-time survival analysis in the critically ill: a deep learning approach using heterogeneous data
Thorsen-Meyer, H., Placido, Davide, Kaas-Hansen, Benjamin Skov, Nielsen, A. P., Lange, Theis, Nielsen, A. B., Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Belling, K., Perner, Anders & Brunak, Søren, 2022, In: npj Digital Medicine. 5, 10 p., 142.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic and explainable machine learning prediction of mortality in patients in the intensive care unit: a retrospective study of high-frequency data in electronic patient records
Thorsen-Meyer, H., Nielsen, A. B., Nielsen, A. P., Kaas-Hansen, Benjamin Skov, Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Dybdahl, L., Spangsege, L., Hulsen, P., Belling, K., Brunak, Søren & Perner, Anders, 2020, In: The Lancet Digital Health. 2, 4, p. e179–91 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abnormal serum levels of magnesium, phosphate, and zinc in ICU patients—Characteristics, management, and outcomes: The WhyTrace cohort study
Vesterlund, G. K., Thorsen-Meyer, H. C., Møller, Morten Hylander, Brunak, Søren, Strøm, T., Perner, Anders & Kaas-Hansen, Benjamin Skov, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 925-935 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low serum levels of magnesium, phosphate, and zinc in ICU patients. Prevalence, management, characteristics, and outcomes. Protocol and statistical analysis plan for The WhyTrace cohort study
Vesterlund, G. K., Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, Møller, Morten Hylander & Perner, Anders, May 2022, medRxiv.Research output: Working paper › Preprint
- Published
Seek COVER: using a disease proxy to rapidly develop and validate a personalized risk calculator for COVID-19 outcomes in an international network
Williams, R. D., Markus, A. F., Yang, C., Duarte-Salles, T., DuVall, S. L., Falconer, T., Jonnagaddala, J., Kim, C., Rho, Y., Williams, A. E., Machado, A. A., An, M. H., Aragón, M., Areia, C., Burn, E., Choi, Y. H., Drakos, I., Abrahão, M. T. F., Fernández-Bertolín, S., Hripcsak, G. & 28 others, , 2022, In: BMC Medical Research Methodology. 22, 13 p., 35.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 185059892
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Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
79
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Dynamic and explainable machine learning prediction of mortality in patients in the intensive care unit: a retrospective study of high-frequency data in electronic patient records
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
63
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Different Original and Biosimilar TNF Inhibitors Similarly Reduce Joint Destruction in Rheumatoid Arthritis-A Network Meta-Analysis of 36 Randomized Controlled Trials
Research output: Contribution to journal › Review › Research › peer-review
Published