Anne Tybjærg-Hansen

Anne Tybjærg-Hansen

Clinical Professor

Member of:

  • Clinical Biochemistry


  1. 2012
  2. Published

    Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays

    Smith, F. A., Howard, P., Shah, S., Eriksson, P., Stender, S., Giambartolomei, C., Folkersen, L. W., Tybjærg-Hansen, Anne, Kumari, M., Palmen, J., Hingorani, A. D., Talmud, P. J. & Humphries, S. E., 2012, In: P L o S Genetics. 8, 8, p. e1002908

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Lipoprotein distribution and serum concentrations of 7α-hydroxy-4-cholesten-3-one and bile acids: effects of monogenic disturbances in high-density lipoprotein metabolism

    Steiner, C., Holleboom, A. G., Karuna, R., Motazacker, M. M., Kuivenhoven, J. A., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Rohrer, L., Rentsch, K. M. & von Eckardstein, A., 2012, In: Clinical Science. 122, 8, p. 385-96 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    ß2 -adrenergic receptor Thr164IIe polymorphism, blood pressure and ischaemic heart disease in 66¿750 individuals

    Thomsen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Internal Medicine. 271, 3, p. 305-14 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    ß2-adrenergic receptor polymorphisms, asthma and COPD: two large population-based studies

    Thomsen, M., Nordestgaard, Børge, Sethi, A. A., Tybjærg-Hansen, Anne & Dahl, M., 2012, In: European Respiratory Journal. 39, 3, p. 558-66 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    β(2) -adrenergic receptor Thr164IIe polymorphism, blood pressure and ischaemic heart disease in 66 750 individuals

    Thomsen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Internal Medicine. 271, 3, p. 305-14

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    β2-Adrenergic receptor polymorphisms, asthma and COPD: two large population-based studies

    Thomsen, M., Nordestgaard, Børge, Sethi, A. A., Tybjærg-Hansen, Anne & Dahl, M., 2012, In: European Respiratory Journal. 39, 3, p. 558-66

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    ß2-adrenergic receptor Thr164Ile polymorphism, obesity, and diabetes: comparison with FTO, MC4R, and TMEM18 polymorphisms in more than 64,000 individuals

    Thomsen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 6, p. E1074-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    β2-adrenergic receptor Thr164Ile polymorphism, obesity, and diabetes: comparison with FTO, MC4R, and TMEM18 polymorphisms in more than 64,000 individuals

    Thomsen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 6, p. E1074-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis

    Tybjærg-Hansen, Anne, Jørgensen, T. & Emerging Risk Factors Collaboration, E. R. F. C., 2012, In: International Journal of Epidemiology. 41, 5, p. 1419-33 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

    Voight, B. F., Peloso, G. M., Orho-Melander, M., Frikke-Schmidt, R., Barbalic, M., Jensen, M. K., Hindy, G., Hólm, H., Ding, E. L., Johnson, T., Schunkert, H., Samani, N. J., Clarke, R., Hopewell, J. C., Thompson, J. F., Li, M., Thorleifsson, G., Newton-Cheh, C., Musunuru, K., Pirruccello, J. P. & 106 others, Saleheen, D., Chen, L., Stewart, A. F. R., Schillert, A., Thorsteinsdottir, U., Thorgeirsson, G., Anand, S., Engert, J. C., Morgan, T., Spertus, J., Stoll, M., Berger, K., Martinelli, N., Girelli, D., McKeown, P. P., Patterson, C. C., Epstein, S. E., Devaney, J., Burnett, M., Mooser, V., Ripatti, S., Surakka, I., Nieminen, M. S., Sinisalo, J., Lokki, M., Perola, M., Havulinna, A., de Faire, U., Gigante, B., Ingelsson, E., Zeller, T., Wild, P., de Bakker, P. I. W., Klungel, O. H., Maitland-van der Zee, A., Peters, B. J. M., de Boer, A., Grobbee, D. E., Kamphuisen, P. W., Deneer, V. H. M., Elbers, C. C., Onland-Moret, N. C., Hofker, M. H., Wijmenga, C., Verschuren, W. M. M., Boer, J. M. A., van der Schouw, Y. T., Rasheed, A., Frossard, P., Demissie, S., Willer, C., Do, R., Ordovas, J. M., Abecasis, G. R., Boehnke, M., Mohlke, K. L., Daly, M. J., Guiducci, C., Burtt, N. P., Surti, A., Gonzalez, E., Purcell, S., Gabriel, S., Marrugat, J., Peden, J., Erdmann, J., Diemert, P., Willenborg, C., König, I. R., Fischer, M., Hengstenberg, C., Ziegler, A., Buysschaert, I., Lambrechts, D., Van de Werf, F., Fox, K. A., El Mokhtari, N. E., Rubin, D., Schrezenmeir, J., Schreiber, S., Schäfer, A., Danesh, J., Blankenberg, S., Roberts, R., McPherson, R., Watkins, H., Hall, A. S., Overvad, K., Rimm, E., Boerwinkle, E., Tybjærg-Hansen, Anne, Cupples, L. A., Reilly, M. P., Melander, O., Mannucci, P. M., Ardissino, D., Siscovick, D., Elosua, R., Stefansson, K., O'Donnell, C. J., Salomaa, V., Rader, D. J., Peltonen, L., Schwartz, S. M., Altshuler, D. & Kathiresan, S., 2012, In: Lancet. 380, 9841, p. 572-80 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium

    Wassel, C. L., Lamina, C., Nambi, V., Coassin, S., Mukamal, K. J., Ganesh, S. K., Jacobs, D. R., Franceschini, N., Papanicolaou, G. J., Gibson, Q., Yanek, L. R., van der Harst, P., Ferguson, J. F., Crawford, D. C., Waite, L. L., Allison, M. A., Criqui, M. H., McDermott, M. M., Mehra, R., Cupples, L. A. & 41 others, Hwang, S., Redline, S., Kaplan, R. C., Heiss, G., Rotter, J. I., Boerwinkle, E., Taylor, H. A., Eraso, L. H., Haun, M., Li, M., Meisinger, C., O'Connell, J. R., Shuldiner, A. R., Tybjærg-Hansen, Anne, Frikke-Schmidt, R., Kollerits, B., Rantner, B., Dieplinger, B., Stadler, M., Mueller, T., Haltmayer, M., Klein-Weigel, P., Summerer, M., Wichmann, H., Asselbergs, F. W., Navis, G., Leach, I. M., Brown-Gentry, K., Goodloe, R., Assimes, T. L., Becker, D. M., Cooke, J. P., Absher, D. M., Olin, J. W., Mitchell, B. D., Reilly, M. P., Mohler, E. R., North, K. E., Reiner, A. P., Kronenberg, F. & Murabito, J. M., 2012, In: Atherosclerosis. 222, 1, p. 138-47 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Short Telomere Length, Myocardial Infarction, Ischemic Heart Disease, and Early Death

    Weischer, M., Bojesen, Stig Egil, Cawthon, R. M., Freiberg, J. J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 32, p. 822-29

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2013
  15. Published

    GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm

    Bottolo, L., Chadeau-Hyam, M., Hastie, D. I., Zeller, T., Liquet, B., Newcombe, P., Yengo, L., Wild, P. S., Schillert, A., Ziegler, A., Nielsen, S. F., Butterworth, A. S., Ho, W. K., Castagné, R., Munzel, T., Tregouet, D., Falchi, M., Cambien, F., Nordestgaard, B., Fumeron, F. & 7 others, Tybjærg-Hansen, Anne, Froguel, P., Danesh, J., Petretto, E., Blankenberg, S., Tiret, L. & Richardson, S., 2013, In: P L o S Genetics. 9, 8, p. 1-17 17 p., e1003657.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    25-hydroxyvitamin D concentrations and risk of venous thromboembolism in the general population with 18,791 participants

    Brøndum-Jacobsen, P., Benn, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2013, In: Journal of Thrombosis and Haemostasis. 11, 3, p. 423-431

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published
  18. Published

    Total mortality by elevated transferrin saturation in patients with diabetes

    Ellervik, Christina, Andersen, H. U., Tybjærg-Hansen, Anne, Frandsen, M. M., Birgens, H., Nordestgaard, Børge & Mandrup-Poulsen, Thomas, Sep 2013, In: Diabetes Care. 36, 9, p. 2646-54 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Secretory Phospholipase A2-IIA and Cardiovascular Disease

    Holmes, M. V., Simon, T., Exeter, H. J., Folkersen, L. W., Asselbergs, F. W., Guardiola, M., Cooper, J. A., Palmen, J., Hubacek, J. A., Carruthers, K. F., Horne, B. D., Brunisholz, K. D., Mega, J. L., van Iperen, E. P. A., Li, M., Leusink, M., Trompet, S., Verschuren, J. J. W., Hovingh, G. K., Dehghan, A. & 93 others, Nelson, C. P., Kotti, S., Danchin, N., Scholz, M., Haase, C. L., Rothenbacher, D., Swerdlow, D. I., Kuchenbaecker, K. B., Staines-Urias, E., Goel, A., van 't Hooft, F., Gertow, K., de Faire, U., Panayiotou, A. G., Tremoli, E., Baldassarre, D., Veglia, F., Holdt, L. M., Beutner, F., Gansevoort, R. T., Navis, G. J., Mateo Leach, I., Breitling, L. P., Brenner, H., Thiery, J., Dallmeier, D., Franco-Cereceda, A., Boer, J. M. A., Stephens, J. W., Hofker, M. H., Tedgui, A., Hofman, A., Uitterlinden, A. G., Adamkova, V., Pitha, J., Onland-Moret, N. C., Cramer, M. J., Nathoe, H. M., Spiering, W., Klungel, O. H., Kumari, M., Whincup, P. H., Morrow, D. A., Braund, P. S., Hall, A. S., Olsson, A. G., Doevendans, P. A., Trip, M. D., Tobin, M. D., Hamsten, A., Watkins, H., Koenig, W., Nicolaides, A. N., Teupser, D., Day, I. N. M., Carlquist, J. F., Gaunt, T. R., Ford, I., Sattar, N., Tsimikas, S., Schwartz, G. G., Lawlor, D. A., Morris, R. W., Sandhu, M. S., Poledne, R., Maitland-van der Zee, A. H., Khaw, K., Keating, B. J., van der Harst, P., Price, J. F., Mehta, S. R., Yusuf, S., Witteman, J. C. M., Franco, O. H., Jukema, J. W., de Knijff, P., Tybjærg-Hansen, Anne, Rader, D. J., Farrall, M., Samani, N. J., Kivimaki, M., Fox, K. A. A., Humphries, S. E., Anderson, J. L., Boekholdt, S. M., Palmer, T. M., Eriksson, P., Paré, G., Hingorani, A. D., Sabatine, M. S., Mallat, Z., Casas, J. P. & Talmud, P. J., 2013, In: Journal of the American College of Cardiology. 62 , 21, p. 1966–1976 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy

    Hornstrup, L. S., Frikke-Schmidt, R., Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jun 2013, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 33, 6, p. 1441-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Extreme lipoprotein(a) levels and improved cardiovascular risk prediction

    Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 19 Mar 2013, In: Journal of the American College of Cardiology. 61, 11, p. 1146-56 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals

    Khan, T. A., Shah, T., Prieto, D., Zhang, W., Price, J., Fowkes, G. R., Cooper, J., Talmud, P. J., Humphries, S. E., Sundstrom, J., Hubacek, J. A., Ebrahim, S., Lawlor, D. A., Ben-Shlomo, Y., Abdollahi, M. R., Slooter, A. J. C., Szolnoki, Z., Sandhu, M., Wareham, N., Frikke-Schmidt, R. & 29 others, Tybjærg-Hansen, Anne, Fillenbaum, G., Heijmans, B. T., Katsuya, T., Gromadzka, G., Singleton, A., Ferrucci, L., Hardy, J., Worrall, B., Rich, S. S., Matarin, M., Whittaker, J., Gaunt, T. R., Whincup, P., Morris, R., Deanfield, J., Donald, A., Davey Smith, G., Kivimaki, M., Kumari, M., Smeeth, L., Khaw, K., Nalls, M., Meschia, J., Sun, K., Hui, R., Day, I., Hingorani, A. D. & Casas, J. P., 2013, In: International Journal of Epidemiology. 42, 2, p. 475-492 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Elevated Fibrinogen Levels Associate with Risk of Pulmonary Embolism, but not with Deep Venous Thrombosis

    Klovaite, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, M., 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 3, p. 286-93

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study

    Lawlor, D. A., Nordestgaard, Børge, Benn, Marianne, Zuccolo, L., Tybjærg-Hansen, Anne & Davey Smith, G., 14 Mar 2013, In: European Heart Journal (Online).

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    AT1 mutations and risk of atrial fibrillation based on genotypes from 71,000 individuals from the general population

    Marott, S. C. W., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, M., 2013, In: British Journal of Clinical Pharmacology. p. Epub ahead of print

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    YKL-40 levels and atrial fibrillation in the general population

    Marott, S. C. W., Benn, M., Johansen, J. S., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2013, In: International Journal of Cardiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease Consensus Statement of the European Atherosclerosis Society

    Nordestgaard, B. G., Chapman, M. J., Humphries, S. E., Ginsberg, H. N., Masana, L., Descamps, O. S., Wiklund, O., Hegele, R. A., Raal, F. J., Defesche, J. C., Wiegman, A., Santos, R. D., Watts, G. F., Parhofer, K. G., Hovingh, G. K., Kovanen, P. T., Boileau, C., Averna, M., Borén, J., Bruckert, E. & 9 others, Catapano, A. L., Kuivenhoven, J. A., Pajukanta, P., Ray, K., Stalenhoef, A. F. H., Stroes, E., Taskinen, M., Tybjærg-Hansen, Anne & Panel, E. A. S. C., 2013, In: European Heart Journal. 34, 45, p. 3478-3490

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 924951