Cord Herbert Brakebusch
Department of Biomedical Sciences
Blegdamsvej 3
2200 København N
- 1990
- Published
Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.
Engelmann, H., Holtmann, H., Brakebusch, Cord Herbert, Avni, Y. S., Sarov, I., Nophar, Y., Hadas, E., Leitner, O. & Wallach, D., 1990, In: Journal of Biological Chemistry. 265, 24, p. 14497-504 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.
Nophar, Y., Kemper, O., Brakebusch, Cord Herbert, Englemann, H., Zwang, R., Aderka, D., Holtmann, H. & Wallach, D., 1990, In: EMBO Journal. 9, 10, p. 3269-78 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
- Published
Mechanisms controlling the level of receptors for tumor necrosis factor.
Holtmann, H., Brakebusch, Cord Herbert, König, M., Klocke, R., Winzen, R., Resch, K. & Wallach, D., 1991, In: Agents and Actions. 32, 1-2, p. 106-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Soluble and cell surface receptors for tumor necrosis factor.
Wallach, D., Engelmann, H., Nophar, Y., Aderka, D., Kemper, O., Hornik, V., Holtmann, H. & Brakebusch, Cord Herbert, 1991, In: Agents and actions. Supplements. 35, p. 51-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1992
- Published
Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.
Aderka, D., Engelmann, H., Maor, Y., Brakebusch, Cord Herbert & Wallach, D., 1992, In: Journal of Experimental Medicine. 175, 2, p. 323-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor.
Brakebusch, Cord Herbert, Nophar, Y., Kemper, O., Engelmann, H. & Wallach, D., 1992, In: EMBO Journal. 11, 3, p. 943-50 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective decrease in cell surface expression and mRNA level of the 55-kDa tumor necrosis factor receptor during differentiation of HL-60 cells into macrophage-like but not granulocyte-like cells.
Winzen, R., Wallach, D., Engelmann, H., Nophar, Y., Brakebusch, Cord Herbert, Kemper, O., Resch, K. & Holtmann, H., 1992, In: Journal of Immunology. 148, 11, p. 3454-60 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity.
Bigda, J., Beletsky, I., Brakebusch, Cord Herbert, Varfolomeev, Y., Engelmann, H., Bigda, J., Holtmann, H. & Wallach, D., 1994, In: Journal of Experimental Medicine. 180, 2, p. 445-60 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor.
Brakebusch, Cord Herbert, Varfolomeev, E. E., Batkin, M. & Wallach, D., 1994, In: Journal of Biological Chemistry. 269, 51, p. 32488-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Suppression of tumor growth in vivo by local and systemic 90K level increase.
Jallal, B., Powell, J., Zachwieja, J., Brakebusch, Cord Herbert, Germain, L., Jacobs, J., Iacobelli, S. & Ullrich, A., 1995, In: Cancer Research. 55, 15, p. 3223-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional discrepancies between tumor necrosis factor and lymphotoxin alpha explained by trimer stability and distinct receptor interactions.
Schuchmann, M., Hess, S., Bufler, P., Brakebusch, Cord Herbert, Wallach, D., Porter, A., Riethmüller, G. & Engelmann, H., 1995, In: European Journal of Immunology. 25, 8, p. 2183-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Beta 1 integrin is essential for teratoma growth and angiogenesis.
Bloch, W., Forsberg, E., Lentini, S., Brakebusch, Cord Herbert, Martin, K., Krell, H. W., Weidle, U. H., Addicks, K. & Fässler, R., 1997, In: Journal of Cell Biology. 139, 1, p. 265-78 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of the 90K immunostimulator gene is controlled by a promoter with unique features.
Brakebusch, Cord Herbert, Jallal, B., Fusco, O., Iacobelli, S. & Ullrich, A., 1997, In: Journal of Biological Chemistry. 272, 6, p. 3674-82 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules.
Brakebusch, Cord Herbert, Hirsch, E., Potocnik, A. & Fässler, R., 1997, In: Journal of Cell Science. 110 ( Pt 23), p. 2895-904 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence and chromosomal localization of the mouse brevican gene.
Rauch, U., Meyer, H., Brakebusch, Cord Herbert, Seidenbecher, C., Gundelfinger, E. D., Beier, D. R. & Fässler, R., 1997, In: Genomics. 44, 1, p. 15-21 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
90K (MAC-2 BP) gene expression in breast cancer and evidence for the production of 90K by peripheral-blood mononuclear cells.
Fusco, O., Querzoli, P., Nenci, I., Natoli, C., Brakebusch, Cord Herbert, Ullrich, A. & Iacobelli, S., 1998, In: International Journal of Cancer. 79, 1, p. 23-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin.
Sasaki, T., Brakebusch, Cord Herbert, Engel, J. & Timpl, R., 1998, In: EMBO Journal. 17, 6, p. 1606-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effect on TCR:CD3 stimulation of a 90-kD glycoprotein (gp90/Mac-2BP), a member of the scavenger receptor cysteine-rich domain protein family.
Silvestri, B., Calderazzo, F., Coppola, V., Rosato, A., Iacobelli, S., Natoli, C., Ullrich, A., Sures, I., Azam, M., Brakebusch, Cord Herbert, Chieco-Bianchi, L. & Amadori, A., 1998, In: Clinical and Experimental Immunology. 113, 3, p. 394-400 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Beta1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts.
Brakebusch, Cord Herbert, Wennerberg, K., Krell, H. W., Weidle, U. H., Sallmyr, A., Johansson, S. & Fässler, R., 1999, In: Oncogene. 18, 26, p. 3852-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and functional characterization of the human 90K promoter.
Brakebusch, Cord Herbert, Sures, I., Jallal, B., Mossie, K., Fusco, O., Iacobelli, S. & Ullrich, A., 1999, In: Genomics. 57, 2, p. 268-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.
Gimond, C., van Der Flier, A., van Delft, S., Brakebusch, Cord Herbert, Kuikman, I., Collard, J. G., Fässler, R. & Sonnenberg, A., 1999, In: Journal of Cell Biology. 147, 6, p. 1325-40 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrin gene targeting.
Talts, J. F., Brakebusch, Cord Herbert & Fässler, R., 1999, In: Methods in Molecular Biology. 129, p. 153-87 34 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes.
Brakebusch, Cord Herbert, Grose, R., Quondamatteo, F., Ramirez, A., Jorcano, J. L., Pirro, A., Svensson, M., Herken, R., Sasaki, T., Timpl, R., Werner, S. & Fässler, R., 2000, In: EMBO Journal. 19, 15, p. 3990-4003 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased levels of apoptosis in the prefusion neural folds underlie the craniofacial disorder, Treacher Collins syndrome.
Dixon, J., Brakebusch, Cord Herbert, Fässler, R. & Dixon, M. J., 2000, In: Human Molecular Genetics. 9, 10, p. 1473-80 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.
Iba, K., Albrechtsen, Reidar, Gilpin, B., Frohlich, C., Loechel, F., Zolkiewska, A., Ishiguro, K., Kojima, T., Liu, W., Langford, J. K., Sanderson, R. D., Brakebusch, Cord Herbert, Fässler, R. & Wewer, Ulla M., 2000, In: Journal of Cell Biology. 149, 5, p. 1143-56 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5296
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Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency
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208
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Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice
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198
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The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells
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