Michael Askvad Sørensen
Associate Professor
- 1989
- Published
Codon usage determines translation rate in Escherichia coli
Sørensen, Michael Askvad, Kurland, C. G. & Pedersen, Steen, 1989, In: Journal of Molecular Biology. 207, 2, p. 365-77 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
- Published
Measurement of translation rates in vivo at individual codons and implication of these rate differences for gene expression
Sørensen, Michael Askvad, Jensen, K. F. & Pedersen, Steen, 1990, Post-Transcriptional Control of Gene Expression. NATO Asi Series, vol 49. Vol. 49. p. 207-216Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- 1991
- Published
Absolute in vivo translation rates of individual codons in Escherichia coli: The two glutamic acid codons GAA and GAG are translated with a threefold difference in rate
Sørensen, Michael Askvad & Pedersen, Steen, 1991, In: Journal of Molecular Biology. 222, 2, p. 265-280Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cysteine, Even in Low Concentrations, Induces Transient Amino Acid Starvation in Escherichia coli
Sørensen, Michael Askvad & Pedersen, Steen, 1991, In: J. Bacteriol.. Vol.173, no.16, p. 5244-46Research output: Contribution to journal › Journal article › Research › peer-review
- 1992
- Published
The rates of macromolecular chain elongation modulate the initiation frequences for transcription and translation in Escherichia coli
Sørensen, Michael Askvad, Vogel, U., Jensen, K. F. & Pedersen, Steen, 1992, In: Antonie van Leeuwenhoek. International Journal of General and Molecular Microbiology. 63, p. 323-331Research output: Contribution to journal › Journal article › Research
- Published
Decreasing transcription elongation rate in Escherichia coli exposed to amino acid starvation
Vogel, U., Sørensen, Michael Askvad, Pedersen, Steen, Jensen, K. F. & Kilstrup, M., 1992, In: Molecular Microbiology. 6, 15, p. 2191-2200Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Isolation and characterization of mutants with impaired regulation of rpsA, the gene encoding ribosomal protein S1 of Escherichia coli
Rasmussen, M. D., Sørensen, Michael Askvad & Pedersen, Steen, 1993, In: Molecular Genetics and Genomics. 240, p. 23-28Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis of proteins in Escherichia coli is limited by the concentration of free ribosomes
Vind, J., Sørensen, Michael Askvad, Rasmussen, M. D. & Pedersen, Steen, 1993, In: Journal of Molecular Biology. Vol. 231, p. 678-688Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
High Concentrations of ppGpp Decrease the RNA Chain Growth Rate. Implications for Protein Synthesis and Translation Fidelity During Amino Acid Starvation in Escherichia coli
Sørensen, Michael Askvad, Jensen, K. F. & Pedersen, Steen, 1994, In: Journal of Molecular Biology. Vol 236, p. 441-454Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
The modification of the wobble base of tRNA(Glu) modulates the translation rate of glutamic acid codons in vivo
Krüger, M. K., Pedersen, Steen, Hagervall, T. G. & Sørensen, Michael Askvad, 4 Dec 1998, In: Journal of Molecular Biology. 284, 3, p. 621-631 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aminoacylation of hypomodified tRNAGlu in vivo
Krüger, M. K. & Sørensen, Michael Askvad, 1998, In: Journal of Molecular Biology. 284, 3, p. 609-620Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The modification of the wobble base of tRNAGlu modulates the translation rate of glutamic acid codons in vivo
Krüger, M. K., Pedersen, Steen, Hagervall, T. G. & Sørensen, Michael Askvad, 1998, In: J. Mol. Biol.. 284, p. 609-620Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of the Peptide Elongation Rate in vivo
Sørensen, Michael Askvad & Pedersen, Steen, 1998, Protein Synthesis: Methods and protocols. Totowa, N.J., U.S.A.: Humana Press, p. 129-142Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Ribosomal Protein S1 required for translation of most, if not all, natural mRNAs in Escherichia coli in vivo
Sørensen, Michael Askvad, Fricke, J. & Pedersen, Steen, 1998, In: Journal of Molecular Biology. 280, p. 561-569Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Charging Levels of Four tRNA Species in Escherichia coli Rel+ and REL- Strains during Amino Acid Starvation: A Simple Model for the Effect of ppGpp on Translational Accuracy
Sørensen, Michael Askvad, 2001, In: Journal of Molecular Biology. 307, 3, p. 785-798Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Selective charging of tRNA isoacceptors induced by amino-acid starvation
Dittmar, K. A., Sørensen, Michael Askvad, Elf, J., Ehrenberg, M. & Pan, T., 2005, In: EMBO Reports. 6, 2, p. 151–157Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Over Expression of a tRNALeu Isoacceptor Changes Charging Pattern of Leucine tRNAs and Reveals New Codon Reading
Sørensen, Michael Askvad, Elf, J., Bouakaz, E., Tenson, T., Sanyal, S., Björk, G. R. & Ehrenberg, M., 2005, In: Journal of Molecular Biology. 354, 1, p. 16-24Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Pseudouridylation of helix 69 of 23S rRNA is necessary for an effective translation termination.
Ejby, M., Sørensen, Michael Askvad & Pedersen, Steen, 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 49, p. 19410-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correlation between mechanical strength of messenger RNA pseudoknots and ribosomal frameshifting.
Hansen, T. M., Reihani, S. N. S., Oddershede, L. B. & Sørensen, Michael Askvad, 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 14, p. 5830-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
mRNA pseudoknot structures can act as ribosomal roadblocks
Hansen, J. T., Oddershede, L. B. & Sørensen, Michael Askvad, 2012, In: Nucleic Acids Research. 40, 1, p. 303-313 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
A novel complex: a quantum dot conjugated to an active T7 RNA Polymerase
Eriksen, M., Horvath, P., Sørensen, Michael Askvad, Semsey, S., Oddershede, L. B. & Jauffred, Liselotte, 2013, In: Journal of Nanomaterials. 2013, 9 p., 468105.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Force spectroscopy of DNA and RNA: structure and kinetics from single-molecule experiments
Ettlinger, R. B., Sørensen, Michael Askvad & Oddershede, L. B., 2014, Nucleic Acid Nanotechnology. Springer, Vol. 29. p. 23-52 31 p. (Nucleic Acids and Molecular Biology, Vol. 29).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2016
- Published
Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Encoded mRNases
Tian, C., Roghanian, Mohammad, Jørgensen, M. G., Sneppen, Kim, Sørensen, Michael Askvad, Gerdes, K. & Mitarai, Namiko, Jul 2016, In: Journal of Bacteriology. 198, 14, p. 1918-1926Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Prophages and growth dynamics confound experimental results with antibiotic-tolerant persister cells
Harms, A., Fino, C., Sørensen, Michael Askvad, Semsey, S. & Gerdes, K., 12 Dec 2017, In: mBio. 8, 6, 18 p., e01964-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of the abundance and charging levels of transfer RNAs in Escherichia coli
Stenum, T. S., Sørensen, Michael Askvad & Svenningsen, Sine Lo, 22 Aug 2017, In: Journal of Visualized Experiments. 126, e56212.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transfer RNA is highly unstable during early amino acid starvation in Escherichia coli
Svenningsen, Sine Lo, Kongstad, M., Stenum, T. S., Muñoz Gomez, A. J. & Sørensen, Michael Askvad, Jan 2017, In: Nucleic Acids Research. 45, 2, p. 793-804 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Ribosome Hibernation
Prossliner, T., Winther, K. S., Sørensen, Michael Askvad & Gerdes, K., 2018, In: Annual Review of Genetics. 52, p. 321-348Research output: Contribution to journal › Review › Research › peer-review
- Published
Transfer RNA instability as a stress response in Escherichia coli: rapid dynamics of the tRNA pool as a function of demand
Sørensen, Michael Askvad, Fehler, A. O. & Svenningsen, Sine Lo, 2018, In: RNA Biology. 15, 4/5, p. 586-593 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Short-term kinetics of rRNA degradation in Escherichia coli upon starvation for carbon, amino acid, or phosphate
Fessler, M., Gummesson, Bertil, Charbon, Godefroid, Svenningsen, Sine Lo & Sørensen, Michael Askvad, 2020, In: Molecular Microbiology. 113, 5, p. 951-963 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Valine-Induced Isoleucine Starvation in Escherichia coli K-12 Studied by Spike-In Normalized RNA Sequencing
Gummesson, Bertil, Shah, S. A., Borum, A. S., Fessler, M., Mitarai, Namiko, Sørensen, Michael Askvad & Svenningsen, Sine Lo, 2020, In: Frontiers in Genetics. 11, 17 p., 144.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Hibernation factors directly block ribonucleases from entering the ribosome in response to starvation: [+ erratum]
Prossliner, T., Gerdes, K., Sørensen, Michael Askvad & Winther, K. S., 2021, In: Nucleic Acids Research. 49, 4, p. 2226-2239 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Three Ribosomal Operons of Escherichia coli Contain Genes Encoding Small RNAs That Interact With Hfq and CsrA in vitro
Stenum, T. S., Kongstad, M., Holmqvist, E., Kallipolitis, B., Svenningsen, Sine Lo & Sørensen, Michael Askvad, 2021, In: Frontiers in Microbiology. 12, 18 p., 625585.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polyamines are Required for tRNA Anticodon Modification in Escherichia coli
Winther, K. S., Sørensen, Michael Askvad & Svenningsen, Sine Lo, 2021, In: Journal of Molecular Biology. 433, 15, 14 p., 167073.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Escherichia coli protein synthesis is limited by mRNA availability rather than ribosomal capacity during phosphate starvation
Espinosa, R., Sørensen, Michael Askvad & Svenningsen, Sine Lo, 2022, In: Frontiers in Microbiology. 13, 13 p., 989818.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct Survival, Growth Lag, and rRNA Degradation Kinetics during Long-Term Starvation for Carbon or Phosphate
Himeoka, Y., Gummesson, Bertil, Sørensen, Michael Askvad, Svenningsen, Sine Lo & Mitarai, Namiko, 20 Apr 2022, In: mSphere. 7, 3, 12 p., e01006-21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Existence of log-phase Escherichia coli persisters and lasting memory of a starvation pulse
Svenningsen, Mikkel Skjoldan, Svenningsen, Sine Lo, Sørensen, Michael Askvad & Mitarai, Namiko, 2022, In: Life Science Alliance. 5, 2, 9 p., e202101076.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin-antitoxin system
Bærentsen, R. L., Nielsen, S. V., Skjerning, R. B., Lyngsø, J., Bisiak, F., Pedersen, J. S., Gerdes, K., Sørensen, Michael Askvad & Brodersen, D. E., 2023, In: eLife. 12, 20 p., RP90400.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3948
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A novel complex: a quantum dot conjugated to an active T7 RNA Polymerase
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
239
downloads
Prophages and growth dynamics confound experimental results with antibiotic-tolerant persister cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
139
downloads
Transfer RNA is highly unstable during early amino acid starvation in Escherichia coli
Research output: Contribution to journal › Journal article › Research › peer-review
Published