Increased muscle interstitial levels of inflammatory cytokines in polymyalgia rheumatica
Research output: Contribution to journal › Journal article › Research › peer-review
Polymyalgia rheumatica (PMR) is characterized by aching of the proximal muscles and increased blood levels of markers of inflammation. Despite the muscle complaints, the current view is that symptoms are caused by inflammation in synovial structures. The purpose of this study was to elucidate the disease mechanisms in symptomatic muscles by measuring interstitial levels of cytokines before and after prednisolone treatment.
|Journal||Arthritis & Rheumatism|
|Number of pages||8|
|Publication status||Published - 2010|
- Aged, Aged, 80 and over, C-Reactive Protein, Chemokine CCL2, Cytokines, Female, Glucocorticoids, Humans, Interleukin-1alpha, Interleukin-1beta, Interleukin-6, Interleukin-8, Male, Middle Aged, Muscle, Skeletal, Polymyalgia Rheumatica, Prednisolone, Tumor Necrosis Factor-alpha