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Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials: a meta-analysis of randomized controlled trials

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Standard

Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials : a meta-analysis of randomized controlled trials. / Christensen, R.; Lorenzen, Janne Kunchel; Svith, Carina Roholm; Bartels, E.M.; Melanson, E.L.; Saris, W.H.; Tremblay, A.; Astrup, Arne.

In: Obesity Reviews, Vol. 10, No. 4, 2009, p. 475-486.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Christensen, R, Lorenzen, JK, Svith, CR, Bartels, EM, Melanson, EL, Saris, WH, Tremblay, A & Astrup, A 2009, 'Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials: a meta-analysis of randomized controlled trials' Obesity Reviews, vol. 10, no. 4, pp. 475-486. https://doi.org/10.1111/j.1467-789X.2009.00599.x

APA

Christensen, R., Lorenzen, J. K., Svith, C. R., Bartels, E. M., Melanson, E. L., Saris, W. H., ... Astrup, A. (2009). Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials: a meta-analysis of randomized controlled trials. Obesity Reviews, 10(4), 475-486. https://doi.org/10.1111/j.1467-789X.2009.00599.x

Vancouver

Christensen R, Lorenzen JK, Svith CR, Bartels EM, Melanson EL, Saris WH et al. Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials: a meta-analysis of randomized controlled trials. Obesity Reviews. 2009;10(4):475-486. https://doi.org/10.1111/j.1467-789X.2009.00599.x

Author

Christensen, R. ; Lorenzen, Janne Kunchel ; Svith, Carina Roholm ; Bartels, E.M. ; Melanson, E.L. ; Saris, W.H. ; Tremblay, A. ; Astrup, Arne. / Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials : a meta-analysis of randomized controlled trials. In: Obesity Reviews. 2009 ; Vol. 10, No. 4. pp. 475-486.

Bibtex

@article{2ac304307ab011de8bc9000ea68e967b,
title = "Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials: a meta-analysis of randomized controlled trials",
abstract = "Observational studies have found that dietary calcium intake is inversely related to body weight and body fat mass. One explanatory mechanism is that dietary calcium increases faecal fat excretion. To examine the effect of calcium from dietary supplements or dairy products on quantitative faecal fat excretion, we performed a systematic review with meta-analysis. We included randomized, controlled trials of calcium (supplements or dairy) in healthy subjects, where faecal fat excretion was measured. Meta-analyses used random-effects models with changes in faecal fat excreted expressed as standardized mean differences, as the studies assessed the same outcome but measured in different ways. An increased calcium intake resulted in increased excretion of faecal fat by a standardized mean difference of 0.99 (95{\%} confidence intervals: 0.63-1.34; P < 0.0001; expected to correspond to approximately 2g day(-1)) with moderate heterogeneity (I(2) = 49.5{\%}) indicating some inconsistency in trial outcomes. However, the dairy trials showed homogeneous outcomes (I(2)=0{\%}) indicating consistency among these trials. We estimated that increasing the dairy calcium intake by 1241 mg day(-1) resulted in an increase in faecal fat of 5.2 (1.6-8.8) g day(-1). In conclusion, dietary calcium has the potential to increase faecal fat excretion to an extent that could be relevant for prevention of weight (re-)gain. Long-term studies are required to establish its potential contribution.",
author = "R. Christensen and Lorenzen, {Janne Kunchel} and Svith, {Carina Roholm} and E.M. Bartels and E.L. Melanson and W.H. Saris and A. Tremblay and Arne Astrup",
note = "Keywords: Adolescent; Adult; Calcium, Dietary; Child; Dairy Products; Dietary Supplements; Fatty Acids; Feces; Female; Humans; Lipid Metabolism; Male; Middle Aged; Obesity; Randomized Controlled Trials as Topic; Young Adult",
year = "2009",
doi = "10.1111/j.1467-789X.2009.00599.x",
language = "English",
volume = "10",
pages = "475--486",
journal = "Obesity Reviews",
issn = "1467-7881",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials

T2 - Obesity Reviews

AU - Christensen,R.

AU - Lorenzen,Janne Kunchel

AU - Svith,Carina Roholm

AU - Bartels,E.M.

AU - Melanson,E.L.

AU - Saris,W.H.

AU - Tremblay,A.

AU - Astrup,Arne

N1 - Keywords: Adolescent; Adult; Calcium, Dietary; Child; Dairy Products; Dietary Supplements; Fatty Acids; Feces; Female; Humans; Lipid Metabolism; Male; Middle Aged; Obesity; Randomized Controlled Trials as Topic; Young Adult

PY - 2009

Y1 - 2009

N2 - Observational studies have found that dietary calcium intake is inversely related to body weight and body fat mass. One explanatory mechanism is that dietary calcium increases faecal fat excretion. To examine the effect of calcium from dietary supplements or dairy products on quantitative faecal fat excretion, we performed a systematic review with meta-analysis. We included randomized, controlled trials of calcium (supplements or dairy) in healthy subjects, where faecal fat excretion was measured. Meta-analyses used random-effects models with changes in faecal fat excreted expressed as standardized mean differences, as the studies assessed the same outcome but measured in different ways. An increased calcium intake resulted in increased excretion of faecal fat by a standardized mean difference of 0.99 (95% confidence intervals: 0.63-1.34; P < 0.0001; expected to correspond to approximately 2g day(-1)) with moderate heterogeneity (I(2) = 49.5%) indicating some inconsistency in trial outcomes. However, the dairy trials showed homogeneous outcomes (I(2)=0%) indicating consistency among these trials. We estimated that increasing the dairy calcium intake by 1241 mg day(-1) resulted in an increase in faecal fat of 5.2 (1.6-8.8) g day(-1). In conclusion, dietary calcium has the potential to increase faecal fat excretion to an extent that could be relevant for prevention of weight (re-)gain. Long-term studies are required to establish its potential contribution.

AB - Observational studies have found that dietary calcium intake is inversely related to body weight and body fat mass. One explanatory mechanism is that dietary calcium increases faecal fat excretion. To examine the effect of calcium from dietary supplements or dairy products on quantitative faecal fat excretion, we performed a systematic review with meta-analysis. We included randomized, controlled trials of calcium (supplements or dairy) in healthy subjects, where faecal fat excretion was measured. Meta-analyses used random-effects models with changes in faecal fat excreted expressed as standardized mean differences, as the studies assessed the same outcome but measured in different ways. An increased calcium intake resulted in increased excretion of faecal fat by a standardized mean difference of 0.99 (95% confidence intervals: 0.63-1.34; P < 0.0001; expected to correspond to approximately 2g day(-1)) with moderate heterogeneity (I(2) = 49.5%) indicating some inconsistency in trial outcomes. However, the dairy trials showed homogeneous outcomes (I(2)=0%) indicating consistency among these trials. We estimated that increasing the dairy calcium intake by 1241 mg day(-1) resulted in an increase in faecal fat of 5.2 (1.6-8.8) g day(-1). In conclusion, dietary calcium has the potential to increase faecal fat excretion to an extent that could be relevant for prevention of weight (re-)gain. Long-term studies are required to establish its potential contribution.

U2 - 10.1111/j.1467-789X.2009.00599.x

DO - 10.1111/j.1467-789X.2009.00599.x

M3 - Journal article

VL - 10

SP - 475

EP - 486

JO - Obesity Reviews

JF - Obesity Reviews

SN - 1467-7881

IS - 4

ER -

ID: 13367801