Differential nongenetic impact of birth weight versus third-trimester growth velocity on glucose metabolism and magnetic resonance imaging abdominal obesity in young healthy twins
Research output: Contribution to journal › Journal article
Low birth weight is associated with type 2 diabetes, which to some extent may be mediated via abdominal adiposity and insulin resistance. Fetal growth velocity is high during the third trimester, constituting a potential critical window for organ programming. Intra-pair differences among monozygotic twins are instrumental in determining nongenetic associations between early environment and adult metabolic phenotype.
|Journal||Journal of Clinical Endocrinology and Metabolism|
|Number of pages||9|
|Publication status||Published - 2011|
- Adolescent, Birth Weight, Body Composition, Female, Glucose, Glucose Clamp Technique, Humans, Infant, Low Birth Weight, Infant, Newborn, Insulin, Insulin Resistance, Male, Obesity, Abdominal, Sex Factors, Twins, Young Adult