Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

Research output: Contribution to journalJournal articleResearchpeer-review

T W Boesgaard, N Grarup, Torben Jørgensen, Knut Borch-Johnsen, T Hansen, Oluf Pedersen, Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC)

A meta-analysis of 21 genome-wide association studies identified 11 novel genetic loci implicated in fasting glucose homeostasis. We aimed to evaluate the impact of these variants on insulin release and insulin sensitivity estimated from OGTTs.
Original languageEnglish
Issue number8
Pages (from-to)1647-55
Number of pages9
Publication statusPublished - 1 Aug 2010

    Research areas

  • Denmark, Diacylglycerol Kinase, Female, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Glucose, Humans, Insulin-Secreting Cells, Male, Middle Aged, Receptors, Adrenergic, alpha-2, Transcription Factors

ID: 33501934