Toxicity of chlorhexidine irrigation in chronic postpneumonectomy empyema

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A Friis-Møller, S Brynitz, Per Jess

Three patients with chronic Staphylococcus aureus empyema following pneumonectomy were treated with continuous chlorhexidine (0.02%) irrigation of the cavity. The empyema became sterile, but after a few days symptoms of cerebral intoxication appeared in all three patients. The symptoms resolved when the treatment was discontinued. Use of continuous chlorhexidine irrigation treatment of large wounds and cavities is therefore to be discouraged.
Original languageEnglish
JournalScandinavian Journal of Thoracic and Cardiovascular Surgery
Volume18
Issue number3
Pages (from-to)243-4
Number of pages2
ISSN0036-5580
Publication statusPublished - 1 Jan 1984
Externally publishedYes

ID: 32645465