The HETE Is on FFAR1 and Pancreatic Islet Cells

Research output: Contribution to journalJournal articleResearchpeer-review

It is known but generally unappreciated that the fatty acid receptor FFAR1 (GPR40) is responsible for a major part of glucose-induced insulin secretion. This puzzling fact is now explained by Tunaru et al. (2018), who demonstrate that glucose-induced 20-hydroxyeicosatetraenoic acid (20-HETE) amplifies insulin secretion through autocrine activation of FFAR1.

Original languageEnglish
JournalCell Metabolism
Issue number2
Pages (from-to)273-275
Number of pages3
Publication statusPublished - 2018

    Research areas

  • Journal Article

ID: 189764824