The HETE Is on FFAR1 and Pancreatic Islet Cells
Research output: Contribution to journal › Journal article › Research › peer-review
It is known but generally unappreciated that the fatty acid receptor FFAR1 (GPR40) is responsible for a major part of glucose-induced insulin secretion. This puzzling fact is now explained by Tunaru et al. (2018), who demonstrate that glucose-induced 20-hydroxyeicosatetraenoic acid (20-HETE) amplifies insulin secretion through autocrine activation of FFAR1.
|Number of pages||3|
|Publication status||Published - 2018|
- Journal Article