The effect of sertindole on QTD and TPTE
Research output: Contribution to journal › Journal article › Research › peer-review
J Nielsen, M P Andersen, Claus Graff, Jørgen K. Kanters, Thomas Bork Hardahl, J Dybbro, Johannes J. Struijk, J M Meyer, E Toft
Recent research suggests that other surrogate markers than QTc, including QTc dispersion and Tpeak-Tend, may better correlate with cardiac arrhythmia risk. While sertindole significantly prolongs the QTc interval, the effects on other markers of arrhythmia risk, such as QTc dispersion and Tpeak-Tend are unknown.
|Book series||Acta Psychiatrica Scandinavica. Supplementum|
|Number of pages||4|
|Publication status||Published - 1 May 2010|
- Adult, Antipsychotic Agents, Denmark, Electrocardiography, Female, Heart Rate, Humans, Imidazoles, Indoles, Long QT Syndrome, Male, Middle Aged, Prospective Studies, Safety-Based Drug Withdrawals, Schizophrenia, Signal Processing, Computer-Assisted, Torsades de Pointes