The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals

Research output: Contribution to journalJournal articleResearchpeer-review

N Grarup, M Overvad, T Sparsø, D R Witte, C Pisinger, Torben Jørgensen, T Yamauchi, K Hara, S Maeda, T Kadowaki, T Hansen, Oluf Pedersen

A genome-wide association study in the Japanese population reported two genome-wide significant loci associated with type 2 diabetes of which the VPS13C/C2CD4A/C2CD4B locus was replicated in Europeans. We looked for potential associations between the diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant and diabetes-related intermediary traits.
Original languageEnglish
JournalDiabetologica
Volume54
Issue number4
Pages (from-to)789-94
Number of pages6
ISSN1432-0428
DOIs
Publication statusPublished - 2011

ID: 33506255