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The association between malaria parasitaemia, erythrocyte polymorphisms, malnutrition and anaemia in children less than 10 years in Senegal: a case control study

Research output: Contribution to journalJournal article

Roger C K Tine, Magatte Ndiaye, Helle Holm Hansson, Cheikh T Ndour, Babacar Faye, Michael Alifrangis, K Sylla, Jean L Ndiaye, Pascal Magnussen, Ib C Bygbjerg, Oumar Gaye

BACKGROUND:Malaria and anaemia (Haemoglobin= 11 g/dl. For each participant, a physical examination was done and anthropometric data collected prior to a biological assessment which included: malaria parasitaemia infection, intestinal worm carriage, G6PD deficiency, sickle cell disorders, and alpha-talassaemia.RESULTS:Three hundred and fifty two children 5 years (aOR=0.03, 95%CI0.01-0.08]). Stratified by age group, anaemia was significantly associated with stunting in children less than 5 years (aOR=3.1 95%CI1.4 -- 6.8]), with, sickle cell disorders (aOR=3.5 95%CI 1.4 -- 9.0]), alpha-thalassemia (or=2.4 95%CI1.1--5.3]) and stunting (aOR=3.6 95%CI 1.6--8.2]) for children above 5 years. No association was found between G6PD deficiency, intestinal worm carriage and children's gender.CONCLUSION:Malaria parasitaemia, stunting and haemoglobin genetic disorders represented the major causes of anaemia among study participants. Anaemia control in this area could be achieved by developing integrated interventions targeting both malaria and malnutrition.
Original languageEnglish
JournalBMC Research Notes
Volume5
Issue number1
Pages (from-to)565
Number of pages1
ISSN1756-0500
DOIs
StatePublished - 2012

    Research areas

  • Anemia, Anemia, Sickle Cell, Animals, Case-Control Studies, Child, Child, Preschool, Entamoeba, Erythrocytes, Female, Giardia lamblia, Glucosephosphate Dehydrogenase, Hemoglobins, Humans, Infant, Malaria, Male, Malnutrition, Parasitemia, Polymorphism, Genetic, Risk Factors, Schistosoma haematobium, Schistosoma mansoni, Senegal, Strongyloides stercoralis, alpha-Thalassemia

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