Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects
Research output: Contribution to journal › Journal article › Research › peer-review
The type 2 iodothyronine deiodinase (D2) catalyzes the conversion of T(4) to the active form of thyroid hormone, which is a critical regulator of thermogenesis and glucose metabolism. A Thr92Ala polymorphism in the gene encoding D2 (DIO2) has been reported to associate with insulin resistance.
|Journal||Journal of Clinical Endocrinology and Metabolism|
|Number of pages||4|
|Publication status||Published - 2007|
- Adult, Cohort Studies, Diabetes Mellitus, Type 2, European Continental Ancestry Group, Female, Humans, Insulin Resistance, Iodide Peroxidase, Male, Middle Aged, Obesity, Phenotype, Polymorphism, Genetic