Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects

Research output: Contribution to journalJournal articleResearchpeer-review

A P Gjesing, G Andersen, A Albrechtsen, C Glümer, K Borch-Johnsen, T Jørgensen, T Hansen, O Pedersen

Activation of the beta(1)-adrenergic receptor (ADRB1) causes increased lipolysis in adipose tissue and enhances cardiac output. Analysis of the association of the functional ADRB1 Arg389Gly variant with obesity and hypertension has given ambiguous results. To clarify the potential impact of this variant on obesity and hypertension in the general population, we examined the Arg389Gly variant in a relatively large-scale population-based study.
Original languageEnglish
JournalDiabetic Medicine
Volume24
Issue number4
Pages (from-to)392-7
Number of pages6
ISSN0742-3071
DOIs
Publication statusPublished - Apr 2007

    Research areas

  • Adult, Aged, Alleles, Denmark, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Epidemiologic Studies, Female, Genotype, Humans, Hypertension, Male, Middle Aged, Obesity, Polymorphism, Genetic, Receptors, Adrenergic, beta-1

ID: 45583425