Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites

Research output: Contribution to journalJournal articleResearchpeer-review

Thomas Sparsø, Meena Shaheen Hussain, Knut Borch-Johnsen, Torben Jørgensen, Sten Madsbad, Torben Hansen, Oluf Pedersen, Gitte Andersen

Calsequestrin 1 (CASQ1) is a calcium storage protein of fast-twitch skeletal muscle cells. In previous human association studies the results have been contradictory regarding the association between a CASQ1 rs2275703 polymorphism and type 2 diabetes. In the present study of the CASQ1 rs2275703 polymorphism in 7,088 Danish whites the allele frequency and genotype distribution did not differ between type 2 diabetic patients and glucose-tolerant control subjects, neither was found any association with diabetes-related quantitative traits.
Original languageEnglish
JournalMolecular Genetics and Metabolism
Issue number3
Pages (from-to)278-282
Number of pages5
Publication statusPublished - 2007

    Research areas

  • Blood Glucose, Calcium-Binding Proteins, Case-Control Studies, Denmark, Diabetes Mellitus, Type 2, Dyslipidemias, Ethnic Groups, European Continental Ancestry Group, Female, Gene Frequency, Genotype, Glucose Tolerance Test, Humans, Insulin, Male, Middle Aged, Mitochondrial Proteins, Obesity, Polymorphism, Single Nucleotide

ID: 4042542