Should the indications for prenatal chromosome analysis be changed?

Research output: Contribution to journalJournal articleResearchpeer-review

J Philip, J Bang, Mette Madsen

Amniocentesis for chromosome analysis was performed in 1086 pergnant women, 739 of whom had an increased risk of giving birth to a child with chromosome abnormalities. Such abnormalities were found in almost identical proportions among the fetuses with an increased risk (1.2%) and among those with no increased risk (1.4%). Findings in several other studies seem to confirm that there is no significant difference between the risk groups in the proportion of abnormalities found. This suggests that our current risk groups may not be the right ones, but a much larger study is needed to confirm this.
Original languageEnglish
JournalBritish medical journal
Issue number6095
Pages (from-to)1117-9
Number of pages2
Publication statusPublished - 1977

Bibliographical note

Keywords: Amniocentesis; Chromosome Aberrations; Chromosome Disorders; Evaluation Studies as Topic; Female; Fetal Diseases; Humans; Pregnancy; Prenatal Diagnosis; Risk

ID: 4853578