Reversible hyperinsulinemic hypoglycemia after gastric bypass: a consequence of altered nutrient delivery

Research output: Contribution to journalJournal articleResearchpeer-review

Tracey McLaughlin, Marcia Peck, Jens Holst, Carolyn Deacon

Severe hypoglycemia after Roux-en-Y gastric bypass surgery (RYGB) is an increasingly recognized condition, characterized by neuroglycopenia and inappropriately elevated insulin concentrations that occur primarily in the postprandial state. Both pathophysiology and treatment of this disorder remain elusive, but it has been postulated that hyperplasia and/or hypertrophy of beta-cells due to morbid obesity and/or postsurgical nesidioblastosis may contribute.
Original languageEnglish
JournalJournal of Clinical Endocrinology and Metabolism
Volume95
Issue number4
Pages (from-to)1851-5
Number of pages5
ISSN0021-972X
DOIs
Publication statusPublished - Apr 2010

    Research areas

  • Adult, Blood Glucose, Body Mass Index, Female, Gastric Bypass, Gastric Inhibitory Polypeptide, Glucagon, Glucagon-Like Peptide 1, Humans, Hyperinsulinism, Hypoglycemia, Insulin, Nutritional Status, Obesity, Morbid, Postoperative Complications

ID: 32437001