Resistance exercise-induced hypertrophy: A potential role for rapamycin-insensitive mTOR
Research output: Contribution to journal › Review › Research › peer-review
Riki Ogasawara, Thomas Elbenhardt Jensen, Craig A Goodman, Troy A Hornberger
The mechanistic target of rapamycin (mTOR) exerts both rapamycin-sensitive and rapamycin-insensitive signaling events, and the rapamycin-sensitive components of mTOR signaling have been widely implicated in the pathway through which resistance exercise induces skeletal muscle hypertrophy. This review explores the hypothesis that rapamycin-insensitive components of mTOR signaling also contribute to this highly important process.
Summary: This review examines whether both rapamycin-sensitive, and rapamycin-insensitive, components of mTOR signaling contribute to the hypertrophic effects of resistance exercise.
|Journal||Exercise and Sport Sciences Reviews|
|Number of pages||7|
|Publication status||Published - 2019|
- The Faculty of Science - Exercise, Hypertrophy, Protein synthesis, mTOR, mTORC1, mTORC2, Rapamycin