Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)

Research output: Contribution to journalJournal articleResearchpeer-review

A Verbrugghe, M Hesta, S Daminet, I Polis, Jens Juul Holst, J Buyse, B Wuyts, G P J Janssens

In six normal-weight and six obese cats, the metabolic effect of propionate absorbed from the colon was assessed. Two colonic infusions were tested in a crossover design with intervals of 4 weeks. The test solution contained 4 mmol sodium propionate per kg ideal body weight in a 0.2% NaCl solution. Normal saline was given as control solution. Solutions were infused into the hindgut over 30 min. Blood samples were obtained prior to and at various time points after starting the infusion. As body condition did not affect evaluated parameters, all data were pooled. Plasma glucose concentrations showed differences neither over time nor during or after infusion with propionate or control. Plasma amino acid concentrations rose over time (p 
Original languageEnglish
JournalJournal of Animal Physiology and Animal Nutrition (Online)
Issue number6
Pages (from-to)1054-64
Number of pages11
Publication statusPublished - Dec 2012

    Research areas

  • Absorption, Animal Feed, Animal Nutritional Physiological Phenomena, Animals, Cats, Colon, Cross-Over Studies, Diet, Female, Gluconeogenesis, Male, Obesity, Propionates

ID: 45841722