Personalized medicine in psychiatry

Research output: Contribution to journalReviewResearchpeer-review

Ida Kim Wium-Andersen, Maj Vinberg, Lars Vedel Kessing, Roger S. McIntyre

Background: Personalized medicine is a model in which a patient’s unique clinical, genetic, and environmental characteristics are the basis for treatment and prevention. 

Aim, method, and results: This review aims to describe the current tools, phenomenological features, clinical risk factors, and biomarkers used to provide personalized medicine. Furthermore, this study describes the target areas in which they can be applied including diagnostics, treatment selection and response, assessment of risk of side-effects, and prevention. 

Discussion and conclusion: Personalized medicine in psychiatry is challenged by the current taxonomy, where the diagnostic categories are broad and great biological heterogeneity exists within each category. There is, thus, a gap between the current advanced research prospects and clinical practice, and the current taxonomy is, thus, a poor basis for biological research. The discussion proposes possible solutions to narrow this gap and to move psychiatric research forward towards personalized medicine.

Original languageEnglish
JournalNordic Journal of Psychiatry
Volume71
Issue number1
Pages (from-to)12-19
Number of pages8
ISSN0803-9488
DOIs
Publication statusPublished - Jan 2017

    Research areas

  • Biomarkers, diagnostic system, genetics, personalized medicine, psychiatry, RDoC, taxonomy

ID: 180934816