Optogenetik bringer neurale mekanismer frem i lyset og kan blive en ny terapiform

Research output: Contribution to journalJournal articleResearchpeer-review

Tobias Melton Axelsen, Charlotte Amalie Emdal Navntoft, Søren Hofman Christiansen, Jakob Kisbye Dreyer, Jakob Balslev Sørensen, Ulrik Gether, David Paul Drucker Woldbye

Optogenetics is an emergent technology that combines light-sensitive proteins derived from algae, so-called opsins, with genetics. Viral vectors encoding opsins are injected into selective brain regions whereby specific cell populations can be controlled with high precision light pulses delivered via implanted optical fibres. This review focuses on explaining basic principles of optogenetics and describes important insights into neuropsychiatric mechanisms provided by the technology.

Original languageDanish
Article numberV06150501
JournalUgeskrift for Laeger
Volume177
Issue number34
Pages (from-to)2-5
Number of pages4
ISSN0041-5782
Publication statusPublished - 17 Aug 2015

ID: 153338303