Neuromedin U Does Not Act as a Decretin in Rats

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Kuhre et al. investigate the potential of neuromedin U to inhibit glucose-stimulated insulin secretion in a physiological setting. NMU does not affect glucose, insulin, glucagon, and somatostatin. They also cannot detect strong NMU receptor expression on islets, which leads them to conclude that NMU is not a decretin.

Original languageEnglish
JournalCell Metabolism
Volume29
Issue number3
Pages (from-to)719-726.e5
Number of pages13
ISSN1550-4131
DOIs
Publication statusPublished - 2019

    Research areas

  • decretin, glucagon-like peptide 1, insulin secretion, neuromedin U, neuromedin U receptor 1 and 2, type 2 diabetes

ID: 215324913