Neo-antigen specific memory T-cell responses in healthy individuals

Research output: Contribution to journalLetterResearchpeer-review

Morten Orebo Holmström, Hans Carl Hasselbalch, Mads Hald Andersen

The driver mutations in exon 9 of the calreticulin protein have only been identified in patients with myeloid cancers. We recently demonstrated that healthy individuals display strong and frequent T-cell responses towards this mutation. This memory T-cell response is likely evidence of the elimination of mutated cells in healthy individuals.

Original languageEnglish
Article number1599640
Issue number7
Number of pages2
Publication statusPublished - 2019

    Research areas

  • calreticulin, cancer immunoediting, hematological cancer, memory T-cells, Neoantigens

ID: 223256978