Neo-antigen specific memory T-cell responses in healthy individuals
Research output: Contribution to journal › Letter › Research › peer-review
The driver mutations in exon 9 of the calreticulin protein have only been identified in patients with myeloid cancers. We recently demonstrated that healthy individuals display strong and frequent T-cell responses towards this mutation. This memory T-cell response is likely evidence of the elimination of mutated cells in healthy individuals.
|Number of pages||2|
|Publication status||Published - 2019|
- calreticulin, cancer immunoediting, hematological cancer, memory T-cells, Neoantigens