Melanocortin 4 receptor mutations in obese Czech children: studies of prevalence, phenotype development, weight reduction response, and functional analysis

Research output: Contribution to journalJournal articleResearchpeer-review

Irena Hainerová, Lesli H Larsen, Birgitte Holst, Marie Finková, Vojtech Hainer, Jan Lebl, Torben Hansen, Oluf Pedersen

Mutations in the melanocortin 4 receptor gene (MC4R) represent the most common known cause of monogenic human obesity.
Original languageEnglish
JournalJournal of Clinical Endocrinology and Metabolism
Volume92
Issue number9
Pages (from-to)3689-96
Number of pages8
ISSN0021-972X
DOIs
Publication statusPublished - 2007

    Research areas

  • Adolescent, Adult, Body Height, Body Weight, Case-Control Studies, Child, Child, Preschool, Czech Republic, DNA Mutational Analysis, Female, Follow-Up Studies, Gene Frequency, Humans, Male, Models, Biological, Mutation, Obesity, Pedigree, Phenotype, Receptor, Melanocortin, Type 4, Weight Loss

ID: 38456445